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Jinte Middeldorp
Jinte Middeldorp
Brain Center - University Medical Center Utrecht
Geverifieerd e-mailadres voor umcutrecht.nl
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GFAP in health and disease
J Middeldorp, EM Hol
Progress in neurobiology 93 (3), 421-443, 2011
10362011
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice
SA Villeda, KE Plambeck, J Middeldorp, JM Castellano, KI Mosher, J Luo, ...
Nature medicine 20 (6), 659-663, 2014
8932014
Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease
D Gate, N Saligrama, O Leventhal, AC Yang, MS Unger, J Middeldorp, ...
Nature 577 (7790), 399-404, 2020
3212020
Glial fibrillary acidic protein isoform expression in plaque related astrogliosis in Alzheimer's disease
W Kamphuis, J Middeldorp, L Kooijman, JA Sluijs, EJ Kooi, M Moeton, ...
Neurobiology of aging 35 (3), 492-510, 2014
2012014
Longterm quiescent cells in the aged human subventricular neurogenic system specifically express GFAP‐δ
SA Van Den Berge, J Middeldorp, CE Zhang, MA Curtis, BW Leonard, ...
Aging cell 9 (3), 313-326, 2010
1602010
Preclinical assessment of young blood plasma for Alzheimer disease
J Middeldorp, B Lehallier, SA Villeda, SSM Miedema, E Evans, E Czirr, ...
JAMA neurology 73 (11), 1325-1333, 2016
1152016
Ontogeny of hippocampal corticosteroid receptors: effects of antenatal glucocorticoids in human and mouse
CW Noorlander, PNE De Graan, J Middeldorp, J Van Beers, GHA Visser
Journal of Comparative Neurology 499 (6), 924-932, 2006
1152006
Glial fibrillary acidic protein filaments can tolerate the incorporation of assembly-compromised GFAP-δ, but with consequences for filament organization and αB-crystallin …
MD Perng, SF Wen, T Gibbon, J Middeldorp, J Sluijs, EM Hol, RA Quinlan
Molecular Biology of the Cell 19 (10), 4521-4533, 2008
1092008
GFAPδ in radial glia and subventricular zone progenitors in the developing human cortex
J Middeldorp, K Boer, JA Sluijs, L De Filippis, F Encha-Razavi, ...
Development 137 (2), 313-321, 2010
942010
Expression patterns of glial fibrillary acidic protein (GFAP)‐delta in epilepsy‐associated lesional pathologies
L Martinian, K Boer, J Middeldorp, EM Hol, SM Sisodiya, W Squier, ...
Neuropathology and applied neurobiology 35 (4), 394-405, 2009
822009
Synapse pathology in schizophrenia: a meta-analysis of postsynaptic elements in postmortem brain studies
A Berdenis van Berlekom, CH Muflihah, GJLJ Snijders, HD MacGillavry, ...
Schizophrenia bulletin 46 (2), 374-386, 2020
742020
GFAPδ expression in glia of the developmental and adolescent mouse brain
C Mamber, W Kamphuis, NL Haring, N Peprah, J Middeldorp, EM Hol
PLoS One 7 (12), e52659, 2012
622012
Intermediate filament transcription in astrocytes is repressed by proteasome inhibition
J Middeldorp, W Kamphuis, JA Sluijs, D Achoui, CHC Leenaars, ...
The FASEB Journal 23 (8), 2710-2726, 2009
492009
Profiling microglia from Alzheimer’s disease donors and non-demented elderly in acute human postmortem cortical tissue
AM Alsema, Q Jiang, L Kracht, E Gerrits, ML Dubbelaar, A Miedema, ...
Frontiers in Molecular Neuroscience 13, 134, 2020
372020
Specific human astrocyte subtype revealed by affinity purified GFAP+ 1 antibody; unpurified serum cross-reacts with neurofilament-L in Alzheimer
J Middeldorp, SA van den Berge, E Aronica, D Speijer, EM Hol
PLoS One 4 (11), e7663, 2009
372009
Immunohistochemical characterization of the out-of frame splice variants GFAP Δ164/Δexon 6 in focal lesions associated with chronic epilepsy
K Boer, J Middeldorp, WGM Spliet, F Razavi, PC van Rijen, JC Baayen, ...
Epilepsy research 90 (1-2), 99-109, 2010
232010
Methods and compositions for treating aging-associated conditions
A Wyss-Coray, SA Villeda, JM Castellano, J Middeldorp, MS Angst, J Luo
US Patent 10,688,130, 2020
182020
SARS-CoV-2 causes brain inflammation and induces Lewy body formation in macaques
IH Philippens, KP Böszörményi, JA Wubben, ZC Fagrouch, N van Driel, ...
bioRxiv, 2021
172021
Reactive astrocytes as treatment targets in Alzheimer's disease—Systematic review of studies using the APPswePS1dE9 mouse model
T Smit, NAC Deshayes, DR Borchelt, W Kamphuis, J Middeldorp, EM Hol
Glia 69 (8), 1852-1881, 2021
162021
Physiological and pathological ageing of astrocytes in the human brain
M Verkerke, EM Hol, J Middeldorp
Neurochemical Research 46 (10), 2662-2675, 2021
142021
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