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Richard J P Brown
Richard J P Brown
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Identification of conserved residues in the E2 envelope glycoprotein of the hepatitis C virus that are critical for CD81 binding
AM Owsianka, JM Timms, AW Tarr, RJP Brown, TP Hickling, A Szwejk, ...
Journal of virology 80 (17), 8695-8704, 2006
3152006
Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33
AW Tarr, AM Owsianka, JM Timms, PC McClure, RJP Brown, TP Hickling, ...
Hepatology 43 (3), 592-601, 2006
2142006
Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells
CC Colpitts, LM Schang, H Rachmawati, A Frentzen, S Pfaender, ...
Gut 63 (7), 1137-1149, 2014
1932014
In vivo evidence for ribavirin-induced mutagenesis of the hepatitis E virus genome
D Todt, A Gisa, A Radonic, A Nitsche, P Behrendt, PV Suneetha, ...
Gut 65 (10), 1733-1743, 2016
1902016
Clinical course of infection and viral tissue tropism of hepatitis C virus–like nonprimate hepaciviruses in horses
S Pfaender, JMV Cavalleri, S Walter, J Doerrbecker, B Campana, ...
Hepatology 61 (2), 447-459, 2015
1482015
Non-macrophage-tropic human immunodeficiency virus type 1 R5 envelopes predominate in blood, lymph nodes, and semen: implications for transmission and pathogenesis
PJ Peters, WM Sullivan, MJ Duenas-Decamp, J Bhattacharya, ...
Journal of virology 80 (13), 6324-6332, 2006
1312006
Natural reservoirs for homologs of hepatitis C virus
S Pfaender, RJP Brown, T Pietschmann, E Steinmann
Emerging microbes & infections 3 (1), 1-9, 2014
1112014
Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors
PJ Peters, MJ Duenas-Decamp, WM Sullivan, R Brown, C Ankghuambom, ...
Retrovirology 5, 1-17, 2008
1032008
Determination of the human antibody response to the epitope defined by the hepatitis C virus-neutralizing monoclonal antibody AP33
AW Tarr, AM Owsianka, D Jayaraj, RJP Brown, TP Hickling, WL Irving, ...
Journal of General Virology 88 (11), 2991-3001, 2007
1002007
An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission
AW Tarr, P Lafaye, L Meredith, L Damier-Piolle, RA Urbanowicz, A Meola, ...
Hepatology 58 (3), 932-939, 2013
852013
Flunarizine prevents hepatitis C virus membrane fusion in a genotype‐dependent manner by targeting the potential fusion peptide within E1
PM Perin, S Haid, RJP Brown, J Doerrbecker, K Schulze, C Zeilinger, ...
Hepatology 63 (1), 49-62, 2016
732016
Naturally occurring antibodies that recognize linear epitopes in the amino terminus of the hepatitis C virus E2 protein confer noninterfering, additive neutralization
AW Tarr, RA Urbanowicz, D Jayaraj, RJP Brown, JA McKeating, WL Irving, ...
Journal of virology 86 (5), 2739-2749, 2012
732012
Intercompartmental Recombination of HIV-1 Contributes to env Intrahost Diversity and Modulates Viral Tropism and Sensitivity to Entry Inhibitors
RJP Brown, PJ Peters, C Caron, MP Gonzalez-Perez, L Stones, ...
Journal of virology 85 (12), 6024-6037, 2011
722011
Hepatitis C patient-derived glycoproteins exhibit marked differences in susceptibility to serum neutralizing antibodies: genetic subtype defines antigenic but not …
AW Tarr, RA Urbanowicz, MR Hamed, A Albecka, CP McClure, ...
Journal of virology 85 (9), 4246-4257, 2011
692011
A diverse panel of hepatitis C virus glycoproteins for use in vaccine research reveals extremes of monoclonal antibody neutralization resistance
RA Urbanowicz, CP McClure, RJP Brown, T Tsoleridis, MAA Persson, ...
Journal of virology 90 (7), 3288-3301, 2016
682016
Hepatitis E virus (HEV) ORF2 antigen levels differentiate between acute and chronic HEV infection
P Behrendt, B Bremer, D Todt, RJP Brown, A Heim, MP Manns, ...
The Journal of infectious diseases 214 (3), 361-368, 2016
632016
Hepatitis C virus
T Pietschmann, RJP Brown
Trends in microbiology 27 (4), 379-380, 2019
592019
Mutagenic effects of ribavirin on hepatitis E virus—viral extinction versus selection of fitness-enhancing mutations
D Todt, S Walter, RJP Brown, E Steinmann
Viruses 8 (10), 283, 2016
572016
Immune protection against reinfection with nonprimate hepacivirus
S Pfaender, S Walter, E Grabski, D Todt, J Bruening, I Romero-Brey, ...
Proceedings of the National Academy of Sciences 114 (12), E2430-E2439, 2017
562017
Genetic diversity underlying the envelope glycoproteins of hepatitis C virus: structural and functional consequences and the implications for vaccine design
AW Tarr, T Khera, K Hueging, J Sheldon, E Steinmann, T Pietschmann, ...
Viruses 7 (7), 3995-4046, 2015
532015
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