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Richard Brust
Richard Brust
Scripps Florida
Verified email at scripps.edu
Title
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Cited by
Year
Proteins in action: femtosecond to millisecond structural dynamics of a photoactive flavoprotein
R Brust, A Lukacs, A Haigney, K Addison, A Gil, M Towrie, IP Clark, ...
Journal of the American Chemical Society 135 (43), 16168-16174, 2013
772013
Photoexcitation of the blue light using FAD photoreceptor AppA results in ultrafast changes to the protein matrix
A Lukacs, A Haigney, R Brust, RK Zhao, AL Stelling, IP Clark, M Towrie, ...
Journal of the American Chemical Society 133 (42), 16893-16900, 2011
672011
Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPARγ
J Shang, R Brust, SA Mosure, J Bass, P Munoz-Tello, H Lin, TS Hughes, ...
Elife 7, e43320, 2018
642018
Identification of a binding site for unsaturated fatty acids in the orphan nuclear receptor Nurr1
IMS de Vera, PK Giri, P Munoz-Tello, R Brust, J Fuhrmann, ...
ACS chemical biology 11 (7), 1795-1799, 2016
632016
A Comparison of Hybridization between Mottled Ducks (Anas fulvigula)and Mallards (A. platyrhynchos) in Florida and South Carolina using Microsatellite DNA …
CL Williams, RC Brust, TT Fendley, GR Tiller, OE Rhodes
Conservation Genetics 6, 445-453, 2005
592005
BLUF domain function does not require a metastable radical intermediate state
A Lukacs, R Brust, A Haigney, SP Laptenok, K Addison, A Gil, M Towrie, ...
Journal of the American Chemical Society 136 (12), 4605-4615, 2014
562014
A structural mechanism for directing corepressor-selective inverse agonism of PPARγ
R Brust, J Shang, J Fuhrmann, SA Mosure, J Bass, A Cano, Z Heidari, ...
Nature communications 9 (1), 4687, 2018
532018
Ultrafast infrared spectroscopy of an isotope-labeled photoactivatable flavoprotein
A Haigney, A Lukacs, RK Zhao, AL Stelling, R Brust, RR Kim, M Kondo, ...
Biochemistry 50 (8), 1321-1328, 2011
532011
Photoactivation of the BLUF protein PixD probed by the site-specific incorporation of fluorotyrosine residues
AA Gil, SP Laptenok, JN Iuliano, A Lukacs, A Verma, CR Hall, GE Yoon, ...
Journal of the American Chemical Society 139 (41), 14638-14648, 2017
522017
Synergistic regulation of coregulator/nuclear receptor interaction by ligand and DNA
IMS de Vera, J Zheng, S Novick, J Shang, TS Hughes, R Brust, ...
Structure 25 (10), 1506-1518. e4, 2017
512017
A molecular switch regulating transcriptional repression and activation of PPARγ
J Shang, SA Mosure, J Zheng, R Brust, J Bass, A Nichols, LA Solt, ...
Nature Communications 11 (1), 956, 2020
482020
Excited state structure and dynamics of the neutral and anionic flavin radical revealed by ultrafast transient mid-IR to visible spectroscopy
A Lukacs, RK Zhao, A Haigney, R Brust, GM Greetham, M Towrie, ...
The Journal of Physical Chemistry B 116 (20), 5810-5818, 2012
432012
Modification of the orthosteric PPARγ covalent antagonist scaffold yields an improved dual-site allosteric inhibitor
R Brust, H Lin, J Fuhrmann, A Asteian, TM Kamenecka, DJ Kojetin
ACS chemical biology 12 (4), 969-978, 2017
412017
Ultrafast transient mid IR to visible spectroscopy of fully reduced flavins
RK Zhao, A Lukacs, A Haigney, R Brust, GM Greetham, M Towrie, ...
Physical Chemistry Chemical Physics 13 (39), 17642-17648, 2011
382011
Mechanism of the AppABLUF Photocycle Probed by Site-Specific Incorporation of Fluorotyrosine Residues: Effect of the Y21 pKa on the Forward and Reverse …
AA Gil, A Haigney, SP Laptenok, R Brust, A Lukacs, JN Iuliano, J Jeng, ...
Journal of the American Chemical Society 138 (3), 926-935, 2016
362016
Mechanism of the AppABLUF Photocycle Probed by Site-Specific Incorporation of Fluorotyrosine Residues: Effect of the Y21 pKa on the Forward and Reverse …
AA Gil, A Haigney, SP Laptenok, R Brust, A Lukacs, JN Iuliano, J Jeng, ...
Journal of the American Chemical Society 138 (3), 926-935, 2016
362016
Complete proton transfer cycle in GFP and its T203V and S205V mutants
SP Laptenok, A Lukacs, A Gil, R Brust, IV Sazanovich, GM Greetham, ...
Angewandte Chemie International Edition 54 (32), 9303-9307, 2015
332015
Ultrafast Structural Dynamics of BlsA, a Photoreceptor from the Pathogenic Bacterium Acinetobacter baumannii
R Brust, A Haigney, A Lukacs, A Gil, S Hossain, K Addison, CT Lai, ...
The Journal of Physical Chemistry Letters 5 (1), 220-224, 2014
322014
Protein photochromism observed by ultrafast vibrational spectroscopy
A Lukacs, A Haigney, R Brust, K Addison, M Towrie, GM Greetham, ...
The Journal of Physical Chemistry B 117 (40), 11954-11959, 2013
292013
Structural basis of altered potency and efficacy displayed by a major in vivo metabolite of the antidiabetic PPARγ drug pioglitazone
SA Mosure, J Shang, J Eberhardt, R Brust, J Zheng, PR Griffin, S Forli, ...
Journal of medicinal chemistry 62 (4), 2008-2023, 2019
282019
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