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lsoucek
lsoucek
Principal Investigator, Vall d'Hebron Institute of Oncology
Verified email at vhio.net - Homepage
Title
Cited by
Cited by
Year
Modelling Myc inhibition as a cancer therapy
L Soucek, J Whitfield, CP Martins, AJ Finch, DJ Murphy, NM Sodir, ...
Nature 455 (7213), 679-683, 2008
9462008
Drugging the'undruggable'cancer targets
CV Dang, EP Reddy, KM Shokat, L Soucek
Nature Reviews Cancer 17 (8), 502-508, 2017
7472017
Interrogating open issues in cancer precision medicine with patient-derived xenografts
AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ...
Nature Reviews Cancer 17 (4), 254-268, 2017
6432017
Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors
L Soucek, ER Lawlor, D Soto, K Shchors, LB Swigart, GI Evan
Nature medicine 13 (10), 1211-1218, 2007
5762007
Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology
OM Pello, M De Pizzol, M Mirolo, L Soucek, L Zammataro, A Amabile, ...
Blood, The Journal of the American Society of Hematology 119 (2), 411-421, 2012
3692012
Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice
L Soucek, JR Whitfield, NM Sodir, D Massó-Vallés, E Serrano, ...
Genes & development 27 (5), 504-513, 2013
3452013
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead
WH Goodson III, L Lowe, DO Carpenter, M Gilbertson, A Manaf Ali, ...
Carcinogenesis 36 (Suppl_1), S254-S296, 2015
3372015
Strategies to inhibit Myc and their clinical applicability
JR Whitfield, ME Beaulieu, L Soucek
Frontiers in cell and developmental biology 5, 10, 2017
3082017
Design and properties of a Myc derivative that efficiently homodimerizes
L Soucek, M Helmer-Citterich, A Sacco, R Jucker, G Cesareni, S Nasi
Oncogene 17 (19), 2463-2472, 1998
2321998
c-Myc recruits P-TEFb for transcription, cellular proliferation and apoptosis
S Kanazawa, L Soucek, G Evan, T Okamoto, BM Peterlin
Oncogene 22 (36), 5707-5711, 2003
2242003
Endogenous Myc maintains the tumor microenvironment
NM Sodir, LB Swigart, AN Karnezis, D Hanahan, GI Evan, L Soucek
Genes & development 25 (9), 907-916, 2011
2212011
The ups and downs of Myc biology
L Soucek, GI Evan
Current opinion in genetics & development 20 (1), 91-95, 2010
2142010
Temporal dissection of p53 function in vitro and in vivo
MA Christophorou, D Martin-Zanca, L Soucek, ER Lawlor, ...
Nature genetics 37 (7), 718-726, 2005
2112005
Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis
D Annibali, JR Whitfield, E Favuzzi, T Jauset, E Serrano, I Cuartas, ...
Nature communications 5 (1), 4632, 2014
2042014
Omomyc, a potential Myc dominant negative, enhances Myc-induced apoptosis
L Soucek, R Jucker, L Panacchia, R Ricordy, F Tato, S Nasi
Cancer research 62 (12), 3507-3510, 2002
2012002
Intrinsic cell-penetrating activity propels Omomyc from proof of concept to viable anti-MYC therapy
ME Beaulieu, T Jauset, D Massó-Vallés, S Martínez-Martín, P Rahl, ...
Science translational medicine 11 (484), eaar5012, 2019
1882019
Making decisions through Myc
S Nasi, R Ciarapica, R Jucker, J Rosati, L Soucek
FEBS letters 490 (3), 153-162, 2001
1592001
MYC instructs and maintains pancreatic adenocarcinoma phenotype
NM Sodir, RM Kortlever, VJA Barthet, T Campos, L Pellegrinet, S Kupczak, ...
Cancer discovery 10 (4), 588-607, 2020
1422020
The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy
M Savino, D Annibali, N Carucci, E Favuzzi, MD Cole, GI Evan, L Soucek, ...
PloS one 6 (7), e22284, 2011
1422011
The effect of environmental chemicals on the tumor microenvironment
SC Casey, M Vaccari, F Al-Mulla, R Al-Temaimi, A Amedei, ...
Carcinogenesis 36 (Suppl_1), S160-S183, 2015
1282015
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