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Jakob Begun
Jakob Begun
Associate Professor, University of Queensland
Geverifieerd e-mailadres voor mater.uq.edu.au
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13177*2021
Long-Lived C. elegans daf-2 Mutants Are Resistant to Bacterial Pathogens
DA Garsin, JM Villanueva, J Begun, DH Kim, CD Sifri, SB Calderwood, ...
Science 300 (5627), 1921-1921, 2003
6982003
Caenorhabditis elegans as a Model Host for Staphylococcus aureus Pathogenesis
CD Sifri, J Begun, FM Ausubel, SB Calderwood
Infection and immunity 71 (4), 2208-2217, 2003
4152003
The worm has turned–microbial virulence modeled in Caenorhabditis elegans
CD Sifri, J Begun, FM Ausubel
Trends in microbiology 13 (3), 119-127, 2005
3622005
Crystal structure of an Xrcc4–DNA ligase IV complex
BL Sibanda, SE Critchlow, J Begun, XY Pei, SP Jackson, TL Blundell, ...
Nature structural biology 8 (12), 1015-1019, 2001
3362001
High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22
M Gulhane, L Murray, R Lourie, H Tong, YH Sheng, R Wang, A Kang, ...
Scientific reports 6 (1), 28990, 2016
3172016
IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans
A de Luca, SP Smeekens, A Casagrande, R Iannitti, KL Conway, ...
Proceedings of the National Academy of Sciences 111 (9), 3526-3531, 2014
3082014
consensus statements on therapeutic drug monitoring of anti‐tumour necrosis factor therapy in inflammatory bowel diseases
N Mitrev, N Vande Casteele, CH Seow, JM Andrews, SJ Connor, ...
Alimentary pharmacology & therapeutics 46 (11-12), 1037-1053, 2017
286*2017
The LRR and RING domain protein LRSAM1 is an E3 ligase crucial for ubiquitin-dependent autophagy of intracellular Salmonella Typhimurium
A Huett, RJ Heath, J Begun, SO Sassi, LA Baxt, JM Vyas, MB Goldberg, ...
Cell host & microbe 12 (6), 778-790, 2012
2362012
Staphylococcal biofilm exopolysaccharide protects against Caenorhabditis elegans immune defenses
J Begun, JM Gaiani, H Rohde, D Mack, SB Calderwood, FM Ausubel, ...
PLoS pathogens 3 (4), e57, 2007
2312007
Deep Resequencing of GWAS Loci Identifies Rare Variants in CARD9, IL23R and RNF186 That Are Associated with Ulcerative Colitis
M Beaudoin, P Goyette, G Boucher, KS Lo, MA Rivas, C Stevens, ...
PLoS genetics 9 (9), e1003723, 2013
2282013
MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiota
M Koyama, P Mukhopadhyay, IS Schuster, AS Henden, J Hülsdünker, ...
Immunity 51 (5), 885-898. e7, 2019
1832019
Gastrointestinal ultrasound in inflammatory bowel disease: an underused resource with potential paradigm-changing application
RV Bryant, AB Friedman, EK Wright, KM Taylor, J Begun, G Maconi, ...
Gut 67 (5), 973-985, 2018
1482018
Ustekinumab versus adalimumab for induction and maintenance therapy in biologic-naive patients with moderately to severely active Crohn's disease: a multicentre, randomised …
BE Sands, PM Irving, T Hoops, JL Izanec, LL Gao, C Gasink, ...
The Lancet 399 (10342), 2200-2211, 2022
1252022
Staphylococcus aureus Virulence Factors Identified by Using a High-Throughput Caenorhabditis elegans-Killing Model
J Begun, CD Sifri, S Goldman, SB Calderwood, FM Ausubel
Infection and immunity 73 (2), 872-877, 2005
1202005
Genetic coding variant in GPR65 alters lysosomal pH and links lysosomal dysfunction with colitis risk
KG Lassen, CI McKenzie, M Mari, T Murano, J Begun, LA Baxt, G Goel, ...
Immunity 44 (6), 1392-1405, 2016
1192016
DAF-16-Dependent Suppression of Immunity During Reproduction in Caenorhabditis elegans
S Miyata, J Begun, ER Troemel, FM Ausubel
Genetics 178 (2), 903-918, 2008
1142008
Upadacitinib induction and maintenance therapy for Crohn’s disease
EV Loftus Jr, J Panés, AP Lacerda, L Peyrin-Biroulet, G D’Haens, ...
New England Journal of Medicine 388 (21), 1966-1980, 2023
1002023
Substrate-based cyclic peptidomimetics of Phe-Ile-Val that inhibit HIV-1 protease using a novel enzyme-binding mode
DR March, G Abbenante, DA Bergman, RI Brinkworth, W Wickramasinghe, ...
Journal of the American Chemical Society 118 (14), 3375-3379, 1996
931996
Getting the adrenaline going: crystal structure of the adrenaline-synthesizing enzyme PNMT
JL Martin, J Begun, MJ McLeish, JM Caine, GL Grunewald
Structure 9 (10), 977-985, 2001
792001
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