Nuclear glycogenolysis modulates histone acetylation in human non-small cell lung cancers RC Sun, VV Dukhande, Z Zhou, LEA Young, S Emanuelle, CF Brainson, ... Cell metabolism 30 (5), 903-916. e7, 2019 | 100 | 2019 |
Lactate supports a metabolic-epigenetic link in macrophage polarization JT Noe, BE Rendon, AE Geller, LR Conroy, SM Morrissey, LEA Young, ... Science advances 7 (46), eabi8602, 2021 | 81 | 2021 |
Targeting pathogenic Lafora bodies in Lafora disease using an antibody-enzyme fusion MK Brewer, A Uittenbogaard, GL Austin, DM Segvich, A DePaoli-Roach, ... Cell metabolism 30 (4), 689-705. e6, 2019 | 77 | 2019 |
Brain glycogen serves as a critical glucosamine cache required for protein glycosylation RC Sun, LEA Young, RC Bruntz, KH Markussen, Z Zhou, LR Conroy, ... Cell metabolism 33 (7), 1404-1417. e9, 2021 | 62 | 2021 |
Mitochondrial metabolism in major neurological diseases Z Zhou, GL Austin, LEA Young, LA Johnson, R Sun Cells 7 (12), 229, 2018 | 57 | 2018 |
Emerging roles of N-linked glycosylation in brain physiology and disorders LR Conroy, TR Hawkinson, LEA Young, MS Gentry, RC Sun Trends in Endocrinology & Metabolism 32 (12), 980-993, 2021 | 45 | 2021 |
APOΕ4 lowers energy expenditure in females and impairs glucose oxidation by increasing flux through aerobic glycolysis BC Farmer, HC Williams, NA Devanney, MA Piron, GK Nation, DJ Carter, ... Molecular neurodegeneration 16, 1-18, 2021 | 41 | 2021 |
Improved workflow for mass spectrometry–based metabolomics analysis of the heart DA Andres, LEA Young, S Veeranki, TR Hawkinson, BM Levitan, D He, ... Journal of Biological Chemistry 295 (9), 2676-2686, 2020 | 39 | 2020 |
Accurate and sensitive quantitation of glucose and glucose phosphates derived from storage carbohydrates by mass spectrometry LEA Young, CO Brizzee, JKA Macedo, RD Murphy, CJ Contreras, ... Carbohydrate polymers 230, 115651, 2020 | 36 | 2020 |
In situ spatial glycomic imaging of mouse and human Alzheimer's disease brains TR Hawkinson, HA Clarke, LEA Young, LR Conroy, KH Markussen, ... Alzheimer's & Dementia 18 (10), 1721-1735, 2022 | 26 | 2022 |
Activation of Drp1 promotes fatty acids-induced metabolic reprograming to potentiate Wnt signaling in colon cancer X Xiong, S Hasani, LEA Young, DR Rivas, AT Skaggs, R Martinez, ... Cell Death & Differentiation 29 (10), 1913-1927, 2022 | 25 | 2022 |
Regional N-glycan and lipid analysis from tissues using MALDI-mass spectrometry imaging AE Stanback, LR Conroy, LEA Young, TR Hawkinson, KH Markussen, ... STAR protocols 2 (1), 100304, 2021 | 21 | 2021 |
In Situ Analysis of N-Linked Glycans as Potential Biomarkers of Clinical Course in Human Prostate Cancer LR Conroy, AE Stanback, LEA Young, HA Clarke, GL Austin, J Liu, ... Molecular Cancer Research 19 (10), 1727-1738, 2021 | 19 | 2021 |
Oral gavage delivery of stable isotope tracer for in vivo metabolomics HC Williams, MA Piron, GK Nation, AE Walsh, LEA Young, RC Sun, ... Metabolites 10 (12), 501, 2020 | 17 | 2020 |
Loss of Rb1 Enhances Glycolytic Metabolism in Kras-Driven Lung Tumors In Vivo LR Conroy, S Dougherty, T Kruer, S Metcalf, P Lorkiewicz, L He, X Yin, ... Cancers 12 (1), 237, 2020 | 14 | 2020 |
Enhancing lifespan of budding yeast by pharmacological lowering of amino acid pools NL Hepowit, JKA Macedo, LEA Young, K Liu, RC Sun, JA MacGurn, ... Aging (Albany NY) 13 (6), 7846, 2021 | 12 | 2021 |
Spatial metabolomics reveals glycogen as an actionable target for pulmonary fibrosis LR Conroy, HA Clarke, DB Allison, SS Valenca, Q Sun, TR Hawkinson, ... Nature Communications 14 (1), 2759, 2023 | 11 | 2023 |
In situ mass spectrometry imaging reveals heterogeneous glycogen stores in human normal and cancerous tissues LEA Young, LR Conroy, HA Clarke, TR Hawkinson, KE Bolton, ... EMBO Molecular Medicine 14 (11), e16029, 2022 | 11 | 2022 |
Caloric restriction alters postprandial responses of essential brain metabolites in young adult mice LM Yanckello, LEA Young, JD Hoffman, RP Mohney, MA Keaton, E Abner, ... Frontiers in Nutrition 6, 90, 2019 | 11 | 2019 |
Tissue-specific downregulation of fatty acid synthase suppresses intestinal adenoma formation via coordinated reprograming of transcriptome and metabolism in the mouse model of … J Drury, LEA Young, TL Scott, CO Kelson, D He, J Liu, Y Wu, C Wang, ... International Journal of Molecular Sciences 23 (12), 6510, 2022 | 10 | 2022 |