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James E. Dahlman
James E. Dahlman
Geverifieerd e-mailadres voor emory.edu - Homepage
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CRISPR-Cas9 knockin mice for genome editing and cancer modeling
RJ Platt, S Chen, Y Zhou, MJ Yim, L Swiech, HR Kempton, JE Dahlman, ...
Cell 159 (2), 440-455, 2014
19412014
Treating metastatic cancer with nanotechnology
A Schroeder, DA Heller, MM Winslow, JE Dahlman, GW Pratt, R Langer, ...
Nature Reviews Cancer 12 (1), 39-50, 2012
12482012
Emerging frontiers in drug delivery
MW Tibbitt, JE Dahlman, R Langer
Journal of the American Chemical Society 138 (3), 704-717, 2016
9102016
In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight
JE Dahlman, C Barnes, OF Khan, A Thiriot, S Jhunjunwala, TE Shaw, ...
Nature nanotechnology 9 (8), 648-655, 2014
6512014
Drug delivery systems for RNA therapeutics
K Paunovska, D Loughrey, JE Dahlman
Nature Reviews Genetics 23 (5), 265-280, 2022
4812022
Proliferation and recruitment contribute to myocardial macrophage expansion in chronic heart failure
HB Sager, M Hulsmans, KJ Lavine, MB Moreira, T Heidt, G Courties, ...
Circulation research 119 (7), 853-864, 2016
3772016
Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease
JE Dahlman, OO Abudayyeh, J Joung, JS Gootenberg, F Zhang, ...
Nature biotechnology 33 (11), 1159-1161, 2015
2922015
Small RNA combination therapy for lung cancer
W Xue, JE Dahlman, T Tammela, OF Khan, S Sood, A Dave, W Cai, ...
Proceedings of the National Academy of Sciences 111 (34), E3553-E3561, 2014
2672014
Silencing or stimulation? siRNA delivery and the immune system
KA Whitehead, JE Dahlman, RS Langer, DG Anderson
Annual review of chemical and biomolecular engineering 2, 77-96, 2011
2522011
High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
CD Sago, MP Lokugamage, K Paunovska, DA Vanover, CM Monaco, ...
Proceedings of the National Academy of Sciences 115 (42), E9944-E9952, 2018
2342018
Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics
JE Dahlman, KJ Kauffman, Y Xing, TE Shaw, FF Mir, CC Dlott, R Langer, ...
Proceedings of the National Academy of Sciences 114 (8), 2060-2065, 2017
2232017
Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis
PY Chen, L Qin, G Li, Z Wang, JE Dahlman, J Malagon-Lopez, S Gujja, ...
Nature metabolism 1 (9), 912-926, 2019
1962019
Optimization of lipid nanoparticles for the delivery of nebulized therapeutic mRNA to the lungs
MP Lokugamage, D Vanover, J Beyersdorf, MZC Hatit, L Rotolo, ...
Nature biomedical engineering 5 (9), 1059-1068, 2021
1882021
RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction
HB Sager, P Dutta, JE Dahlman, M Hulsmans, G Courties, Y Sun, T Heidt, ...
Science translational medicine 8 (342), 342ra80-342ra80, 2016
1852016
A direct comparison of in vitro and in vivo nucleic acid delivery mediated by hundreds of nanoparticles reveals a weak correlation
K Paunovska, CD Sago, CM Monaco, WH Hudson, MG Castro, ...
Nano letters 18 (3), 2148-2157, 2018
1632018
Challenges in carrier‐mediated intracellular delivery: moving beyond endosomal barriers
MP Stewart, A Lorenz, J Dahlman, G Sahay
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 8 (3 …, 2016
1442016
Nanoparticles containing oxidized cholesterol deliver mRNA to the liver microenvironment at clinically relevant doses
K Paunovska, AJ Da Silva Sanchez, CD Sago, Z Gan, MP Lokugamage, ...
Advanced materials 31 (14), 1807748, 2019
1392019
Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature
OF Khan, EW Zaia, S Jhunjhunwala, W Xue, W Cai, DS Yun, CM Barnes, ...
Nano letters 15 (5), 3008-3016, 2015
1302015
Genetic and hypoxic alterations of the micro RNA‐210‐ISCU 1/2 axis promote iron–sulfur deficiency and pulmonary hypertension
K White, Y Lu, S Annis, AE Hale, BN Chau, JE Dahlman, C Hemann, ...
EMBO molecular medicine 7 (6), 695-713, 2015
1282015
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using particle delivery components
J Dahlman, RJ PLATT, DG Anderson, R Langer, F Zhang
1252015
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