Richard M Sharpe
Richard M Sharpe
MRC University of Edinburgh
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Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract?
RM Sharpe, NE Skakkebaek
The Lancet 341 (8857), 1392-1396, 1993
Male reproductive health and environmental xenoestrogens.
J Toppari, JC Larsen, P Christiansen, A Giwercman, P Grandjean, ...
Environmental health perspectives 104 (suppl 4), 741-803, 1996
Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood
RM Sharpe, C McKinnell, C Kivlin, JS Fisher
REPRODUCTION-CAMBRIDGE- 125 (6), 769-784, 2003
Regulation of spermatogenesis
RM Sharpe
The physiology of reproduction, 1994
A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis
K De Gendt, JV Swinnen, PTK Saunders, L Schoonjans, M Dewerchin, ...
Proceedings of the National Academy of Sciences 101 (5), 1327-1332, 2004
Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism
M Welsh, PTK Saunders, M Fisken, HM Scott, GR Hutchison, LB Smith, ...
The Journal of clinical investigation 118 (4), 1479-1490, 2008
Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production.
RM Sharpe, JS Fisher, MM Millar, S Jobling, JP Sumpter
Environmental health perspectives 103 (12), 1136-1143, 1995
Human ‘testicular dysgenesis syndrome’: a possible model using in‐utero exposure of the rat to dibutyl phthalate
JS Fisher, S Macpherson, N Marchetti, RM Sharpe
Human reproduction 18 (7), 1383-1394, 2003
How strong is the evidence of a link between environmental chemicals and adverse effects on human reproductive health?
RM Sharpe, DS Irvine
Bmj 328 (7437), 447-451, 2004
Public health implications of altered puberty timing
MS Golub, GW Collman, PMD Foster, CA Kimmel, E Rajpert-De Meyts, ...
Pediatrics 121 (Supplement_3), S218-S230, 2008
Immunohistochemical localization of androgen receptors in the rat testis: evidence for stage-dependent expression and regulation by androgens
WJ Bremner, MR Millar, RM Sharpe, PT Saunders
Endocrinology 135 (3), 1227-1234, 1994
Environmental/lifestyle effects on spermatogenesis
RM Sharpe
Philosophical Transactions of the Royal Society B: Biological Sciences 365 …, 2010
Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects
RM Sharpe, NE Skakkebaek
Fertility and sterility 89 (2), e33-e38, 2008
The ‘oestrogen hypothesis’– where do we stand now?1
RM Sharpe
International journal of andrology 26 (1), 2-15, 2003
Comparison of androgen receptor and oestrogen receptor beta immunoexpression in the testes of the common marmoset (Callithrix jacchus) from birth to adulthood: low androgen …
C McKinnell, PT Saunders, HM Fraser, CJ Kelnar, C Kivlin, KD Morris, ...
Reproduction 122 (3), 419-429, 2001
Hormones and testis development and the possible adverse effects of environmental chemicals
RM Sharpe
Toxicology letters 120 (1-3), 221-232, 2001
Comparative effects of neonatal exposure of male rats to potent and weak (environmental) estrogens on spermatogenesis at puberty and the relationship to adult testis size and …
N Atanassova, C McKinnell, KJ Turner, M Walker, JS Fisher, M Morley, ...
Endocrinology 141 (10), 3898-3907, 2000
Steroidogenesis in the fetal testis and its susceptibility to disruption by exogenous compounds
HM Scott, JI Mason, RM Sharpe
Endocrine reviews 30 (7), 883-925, 2009
Pathways of endocrine disruption during male sexual differentiation and masculinisation
RM Sharpe
Best practice & research Clinical endocrinology & metabolism 20 (1), 91-110, 2006
Evidence for inhibin-like activity in bovine follicular fluid
FH De Jong, RM Sharpe
Nature 263 (5572), 71-72, 1976
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