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Michael E. Urbanowski
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Genetics of human susceptibility to active and latent tuberculosis: present knowledge and future perspectives
L Abel, J Fellay, DW Haas, E Schurr, G Srikrishna, M Urbanowski, ...
The Lancet Infectious diseases 18 (3), e64-e75, 2018
1462018
Cavitary tuberculosis: the gateway of disease transmission
ME Urbanowski, AA Ordonez, CA Ruiz-Bedoya, SK Jain, WR Bishai
The Lancet Infectious Diseases, 2020
1202020
Dynamic imaging in patients with tuberculosis reveals heterogeneous drug exposures in pulmonary lesions
AA Ordonez, H Wang, G Magombedze, CA Ruiz-Bedoya, S Srivastava, ...
Nature medicine 26 (4), 529-534, 2020
1022020
A systematic approach for developing bacteria-specific imaging tracers
AA Ordonez, EA Weinstein, LE Bambarger, V Saini, YS Chang, ...
Journal of Nuclear Medicine 58 (1), 144-150, 2017
1012017
Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti–PD-1 in melanoma
LS Cheung, J Fu, P Kumar, A Kumar, ME Urbanowski, EA Ihms, ...
Proceedings of the National Academy of Sciences 116 (8), 3100-3105, 2019
632019
Pharmacokinetics of rifapentine and rifampin in a rabbit model of tuberculosis and correlation with clinical trial data
D Rifat, B Prideaux, RM Savic, ME Urbanowski, TL Parsons, B Luna, ...
Science translational medicine 10 (435), eaai7786, 2018
442018
Pathogenesis and animal models of post-primary (Bronchogenic) tuberculosis, a review
RL Hunter, JK Actor, SA Hwang, A Khan, ME Urbanowski, D Kaushal, ...
Pathogens 7 (1), 19, 2018
382018
Cathepsin K contributes to cavitation and collagen turnover in pulmonary tuberculosis
A Kubler, C Larsson, B Luna, BB Andrade, EP Amaral, M Urbanowski, ...
The Journal of infectious diseases 213 (4), 618-627, 2016
362016
Repetitive aerosol exposure promotes cavitary tuberculosis and enables screening for targeted inhibitors of extensive lung destruction
ME Urbanowski, EA Ihms, K Bigelow, A Kübler, PT Elkington, WR Bishai
The Journal of infectious diseases 218 (1), 53-63, 2018
312018
The integrated stress response mediates necrosis in murine Mycobacterium tuberculosis granulomas
B Bhattacharya, S Xiao, S Chatterjee, ME Urbanowski, AA Ordonez, ...
The Journal of Clinical Investigation, 2020
272020
Matrix metalloproteinase inhibition in a murine model of cavitary tuberculosis paradoxically worsens pathology
AA Ordonez, S Pokkali, J Sanchez-Bautista, MH Klunk, ME Urbanowski, ...
The Journal of infectious diseases 219 (4), 633-636, 2019
272019
Biomarkers for tuberculosis based on secreted, species-specific, bacterial small molecules
SJ Pan, A Tapley, J Adamson, T Little, M Urbanowski, K Cohen, A Pym, ...
The Journal of infectious diseases 212 (11), 1827-1834, 2015
272015
Diverse cavity types and evidence that mechanical action on the necrotic granuloma drives tuberculous cavitation
EA Ihms, ME Urbanowski, WR Bishai
The American journal of pathology 188 (7), 1666-1675, 2018
232018
Assessing whether isoniazid is essential during the first 14 days of tuberculosis therapy: a phase 2a, open-label, randomised controlled trial
A Diacon, S Miyahara, R Dawson, X Sun, E Hogg, K Donahue, ...
The Lancet Microbe 1 (2), e84-e92, 2020
102020
Dual mTORC1/mTORC2 inhibition as a Host-Directed Therapeutic Target in Pathologically Distinct Mouse Models of Tuberculosis
R Tasneen, DS Mortensen, PJ Converse, ME Urbanowski, A Upton, ...
Antimicrobial agents and chemotherapy, AAC. 00253-21, 2021
92021
Effective Host-Directed Therapy for Tuberculosis by Depletion of Myeloid-Derived Suppressor Cells and Related Cells Using a Diphtheria Toxin Fusion Protein
S Parveen, S Lun, ME Urbanowski, M Cardin, J Shen, JR Murphy, ...
The Journal of infectious diseases 224 (11), 1962-1972, 2021
32021
Effective host-directed therapy for tuberculosis by targeted depletion of myeloid-derived suppressor cells using a diphtheria toxin-based fusion protein
S Parveen, S Lun, ME Urbanowski, M Cardin, JR Murphy, WR Bishai
bioRxiv, 2020
22020
The integrated stress response mediates type I interferon driven necrosis in Mycobacterium tuberculosis granulomas
B Bhattacharya, S Xiao, S Chatterjee, M Urbanowski, A Ordonez, EA Ihms, ...
bioRxiv, 499467, 2018
22018
Penetration of rifampin and rifapentine into diseased lung in the rabbit cavity pulmonary disease model of TB
D Rifat, M Urbanowski, B Luna, M Marzinke, V Dartois, R Savic, W Bishai, ...
8th International Workshop on Clinical Pharmacology of Tuberculosis Drugs, 2015
22015
Expanding Latent Tuberculosis Infection Testing and Treatment in Massachusetts Primary Care Clinics via the ECHO Model
D Szkwarko, ME Urbanowski, R Thal, P Iyer, S Foley, LM Randall, ...
Journal of primary care & community health 13, 21501319221119942, 2022
12022
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Articles 1–20