The bile acid chenodeoxycholic acid increases human brown adipose tissue activity EPM Broeders, EBM Nascimento, B Havekes, B Brans, KHM Roumans, ... Cell metabolism 22 (3), 418-426, 2015 | 399 | 2015 |
Low brown adipose tissue activity in endurance-trained compared with lean sedentary men MJ Vosselman, J Hoeks, B Brans, H Pallubinsky, EBM Nascimento, ... International Journal of obesity 39 (12), 1696-1702, 2015 | 213 | 2015 |
Role of PRAS40 in Akt and mTOR signaling in health and disease C Wiza, EBM Nascimento, DM Ouwens American Journal of Physiology-Endocrinology and Metabolism 302 (12), E1453 …, 2012 | 206 | 2012 |
Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1 EBM Nascimento, M Snel, B Guigas, GCM van der Zon, J Kriek, ... Cellular signalling 22 (6), 961-967, 2010 | 120 | 2010 |
Insulin-mediated phosphorylation of the proline-rich Akt substrate PRAS40 is impaired in insulin target tissues of high-fat diet–fed rats EBM Nascimento, M Fodor, GCM van der Zon, IM Jazet, AE Meinders, ... Diabetes 55 (12), 3221-3228, 2006 | 71 | 2006 |
Resveratrol improves ex vivo mitochondrial function but does not affect insulin sensitivity or brown adipose tissue in first degree relatives of patients with type 2 diabetes M de Ligt, YMH Bruls, J Hansen, MF Habets, B Havekes, ... Molecular metabolism 12, 39-47, 2018 | 63 | 2018 |
Human brown adipose tissue: underestimated target in metabolic disease? MPB Moonen, EBM Nascimento, WD van Marken Lichtenbelt Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 51 | 2019 |
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes C Clemmensen, S Jall, M Kleinert, C Quarta, T Gruber, J Reber, S Sachs, ... Nature communications 9 (1), 4304, 2018 | 51 | 2018 |
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes C Clemmensen, S Jall, M Kleinert, C Quarta, T Gruber, J Reber, S Sachs, ... Nature communications 9 (1), 4304, 2018 | 51 | 2018 |
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes C Clemmensen, S Jall, M Kleinert, C Quarta, T Gruber, J Reber, S Sachs, ... Nature communications 9 (1), 4304, 2018 | 51 | 2018 |
Sestrin 3 regulation in type 2 diabetic patients and its influence on metabolism and differentiation in skeletal muscle EBM Nascimento, ME Osler, JR Zierath American Journal of Physiology-Endocrinology and Metabolism 305 (11), E1408 …, 2013 | 43 | 2013 |
PRAS40: target or modulator of mTORC1 signalling and insulin action? EBM Nascimento, DM Ouwens Archives of physiology and biochemistry 115 (4), 163-175, 2009 | 41 | 2009 |
4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue M Grandoch, U Flögel, S Virtue, JK Maier, T Jelenik, C Kohlmorgen, ... Nature metabolism 1 (5), 546-559, 2019 | 35 | 2019 |
The Peroxisome Proliferator-Activated Receptor α is dispensable for cold-induced adipose tissue browning in mice M Defour, W Dijk, P Ruppert, EBM Nascimento, P Schrauwen, S Kersten Molecular metabolism 10, 39-54, 2018 | 35 | 2018 |
Genetic Markers of Brown Adipose Tissue Identity and In Vitro Brown Adipose Tissue Activity in Humans EBM Nascimento, LM Sparks, A Divoux, MW van Gisbergen, ... Obesity 26 (1), 135-140, 2018 | 35 | 2018 |
Over-expression of PRAS40 enhances insulin sensitivity in skeletal muscle C Wiza, A Chadt, M Blumensatt, T Kanzleiter, D Herzfeld De Wiza, ... Archives of physiology and biochemistry 120 (2), 64-72, 2014 | 33 | 2014 |
Atrial natriuretic peptide orchestrates a coordinated physiological response to fuel non-shivering thermogenesis D Carper, M Coue, EBM Nascimento, V Barquissau, D Lagarde, ... Cell Reports 32 (8), 2020 | 32 | 2020 |
ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity LM Sparks, A Gemmink, E Phielix, M Bosma, G Schaart, ... Diabetologia 59, 1030-1039, 2016 | 29 | 2016 |
Knockdown of PRAS40 inhibits insulin action via proteasome-mediated degradation of IRS1 in primary human skeletal muscle cells C Wiza, D Herzfeld de Wiza, EBM Nascimento, S Lehr, H Al-Hasani, ... Diabetologia 56, 1118-1128, 2013 | 26 | 2013 |
Nicotinamide riboside enhances in vitro beta-adrenergic brown adipose tissue activity in humans EBM Nascimento, MPB Moonen, CME Remie, K Gariani, JA Jörgensen, ... The Journal of Clinical Endocrinology & Metabolism 106 (5), 1437-1447, 2021 | 23 | 2021 |