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Devendra Pade
Devendra Pade
Senior Principal Scientist, PKDM, Amgen Inc.
Geverifieerd e-mailadres voor amgen.com
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Pharmacokinetics of caffeic acid phenethyl ester and its catechol‐ring fluorinated derivative following intravenous administration to rats
X Wang, J Pang, JA Maffucci, DS Pade, RA Newman, SM Kerwin, ...
Biopharmaceutics & drug disposition 30 (5), 221-228, 2009
762009
A mechanistic pharmacokinetic model to assess modified oral drug bioavailability post bariatric surgery in morbidly obese patients: interplay between CYP3A gut wall metabolism …
AS Darwich, D Pade, BJ Ammori, M Jamei, DM Ashcroft, ...
Journal of Pharmacy and Pharmacology 64 (7), 1008-1024, 2012
682012
Application of the MechPeff model to predict passive effective intestinal permeability in the different regions of the rodent small intestine and colon
D Pade, M Jamei, A Rostami‐Hodjegan, DB Turner
Biopharmaceutics & drug disposition 38 (2), 94-114, 2017
452017
Evaluation of an In Silico PBPK Post‐Bariatric Surgery Model through Simulating Oral Drug Bioavailability of Atorvastatin and Cyclosporine
AS Darwich, D Pade, K Rowland‐Yeo, M Jamei, A Åsberg, H Christensen, ...
CPT: pharmacometrics & systems pharmacology 2 (6), 1-9, 2013
332013
Canine gastrointestinal physiology: Breeds variations that can influence drug absorption
H Oswald, M Sharkey, D Pade, MN Martinez
European Journal of Pharmaceutics and Biopharmaceutics 97, 192-203, 2015
212015
Comparison of canine and human physiological factors: understanding interspecies differences that impact drug pharmacokinetics
MN Martinez, JP Mochel, S Neuhoff, D Pade
The AAPS journal 23 (3), 59, 2021
192021
Selection of Bioavailability Markers for Herbal Extracts Based on In Silico Descriptors and Their Correlation to In Vitro Permeability
D Pade, S Stavchansky
Molecular Pharmaceutics 5 (4), 665-671, 2008
122008
Population variability in animal health: Influence on dose‐exposure‐response relationships: Part II: Modelling and simulation
MN Martinez, R Gehring, JP Mochel, D Pade, L Pelligand
Journal of veterinary pharmacology and therapeutics 41 (4), E68-E76, 2018
112018
Danazol oral absorption modelling in the fasted dog: An example of mechanistic understanding of formulation effects on drug pharmacokinetics
D Pade, M Jamei, DB Turner, B Mistry, MN Martinez
European Journal of Pharmaceutics and Biopharmaceutics 141, 191-209, 2019
52019
Considerations in the Extrapolation of Drug Toxicity Between Humans and Dogs
MN Martinez, JP Mochel, D Pade
Current Opinion in Toxicology, 2020
42020
A mechanistic framework for the in silico prediction of regional passive gut wall permeability and its inter-individual variability in humans
D Pade, M Jamei, A Rostami Hodjegan, DB Turner
AAPS 2014 W 5106, 2014
42014
Use of in silico predictors, solubility and permeability to select bioavailability and bioequivalence markers in herbal supplements
DS Pade
The University of Texas at Austin, 2007
42007
Use of physiologically based pharmacokinetic (PBPK) models to support canine drug product development
D Pade, M Martinez, B Mistry, M Jamei, A Rostami-Hodjegan
Journal of Veterinary Pharmacology and Therapeutics 38 (Suppl. 1), 99, 2015
32015
Use of in silico physiologically based pharmacokinetic (PBPK) models to predict food effects in dogs
B Mistry, D Pade, A Rostami-Hodjegan, M Jamei, M Martinez
The 2013 American Association of Pharmaceutical Scientists (AAPS) Annual …, 2013
22013
Workshop report: USP workshop on exploring the science of drug absorption
MN Martinez, S Bhoopathy, S Carlert, M Cirit, R Fahmy, T Flanagan, ...
Dissolution Technologies 26 (3), 38-66, 2019
12019
A performance evaluation of Simcyp Dog—A fully mechanistic physiologically based pharmacokinetic dog model based upon a variety of celecoxib IV and oral formulations
D Pade, D Turner, M Jamei, L Antonovic, M Martinez, ...
AAPS Annual Meeting; Washington, DC, 2011
12011
A mechanistic PBPK model for Maraviroc to elucidate the dose related non-linearity in oral absorption using a middle out approach.
D Pade, I Gardner, P Kilford
AAPS PharmSci 360 Annual Meeting and Exposition Boston, MA, USA, 2022, M0930 …, 2022
2022
Development and Verification of a Physiologically Based Pharmacokinetic-Pharmacodynamic (PBPK-PD) Canine Model for Propofol in Greyhounds and Beagles
T Abdulla, D Pade, S Neuhoff, M Jamei, MN Martinez
Annual Meeting of the American Association of Pharmaceuical Scientists, San …, 2019
2019
Development and verification of a physiologically based pharmacokinetic – pharmacodynamic (PBPK-PD) dog model for Irbesartan following oral dose administration
D Pade, S Neuhoff, K Abduljalil, M Jamei
Annual Meeting of the American Association of Pharmaceuical Scientists, San …, 2019
2019
I-03: Integrating a tumour Growth inhibition Model within a Physiologically-Based Pharmacokinetic Model to predict Erlotinib tumour concentrations in Mice
K Abduljalil, RH Rose, D Pade, SK Chirumamilla, C Liu, I Taneja, ...
PAGE 2019 Poster Abstracts, 19, 2019
2019
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