| Muscarinic receptor signaling in the pathophysiology of asthma and COPD R Gosens, J Zaagsma, H Meurs, AJ Halayko Respiratory research 7 (1), 73, 2006 | 421 | 2006 |
| Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma SS An, TR Bai, JHT Bates, JL Black, RH Brown, V Brusasco, P Chitano, ... European Respiratory Journal 29 (5), 834-860, 2007 | 414 | 2007 |
| Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling R Gosens, IST Bos, J Zaagsma, H Meurs American journal of respiratory and critical care medicine 171 (10), 1096-1102, 2005 | 272 | 2005 |
| Inhibition of allergen-induced airway remodelling by tiotropium and budesonide: a comparison IST Bos, R Gosens, AB Zuidhof, D Schaafsma, AJ Halayko, H Meurs, ... European Respiratory Journal 30 (4), 653-661, 2007 | 225 | 2007 |
| Role of caveolin-1 in p42/p44 MAP kinase activation and proliferation of human airway smooth muscle R Gosens, GL Stelmack, G Dueck, KD McNeill, A Yamasaki, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 291 (3 …, 2006 | 191 | 2006 |
| Airway structural components drive airway smooth muscle remodeling in asthma BGJ Dekkers, H Maarsingh, H Meurs, R Gosens Proceedings of the American Thoracic Society 6 (8), 683-692, 2009 | 160 | 2009 |
| The WNT signaling pathway from ligand secretion to gene transcription: molecular mechanisms and pharmacological targets HA Baarsma, M Königshoff, R Gosens Pharmacology & therapeutics 138 (1), 66-83, 2013 | 146 | 2013 |
| Activation of WNT/β-catenin signaling in pulmonary fibroblasts by TGF-β1 is increased in chronic obstructive pulmonary disease HA Baarsma, AIR Spanjer, G Haitsma, LHJM Engelbertink, H Meurs, ... PloS one 6 (9), e25450, 2011 | 136 | 2011 |
| Alternative mechanisms for tiotropium ED Bateman, S Rennard, PJ Barnes, PV Dicpinigaitis, R Gosens, ... Pulmonary pharmacology & therapeutics 22 (6), 533-542, 2009 | 126 | 2009 |
| Airway hyperresponsiveness in asthma: lessons from in vitro model systems and animal models H Meurs, R Gosens, J Zaagsma European Respiratory Journal 32 (2), 487-502, 2008 | 120 | 2008 |
| Tiotropium inhibits pulmonary inflammation and remodelling in a guinea pig model of COPD T Pera, A Zuidhof, J Valadas, M Smit, RG Schoemaker, R Gosens, ... European Respiratory Journal 38 (4), 789-796, 2011 | 119 | 2011 |
| Phenotype and functional plasticity of airway smooth muscle: role of caveolae and caveolins AJ Halayko, T Tran, R Gosens Proceedings of the American Thoracic Society 5 (1), 80-88, 2008 | 115 | 2008 |
| Acetylcholine: a novel regulator of airway smooth muscle remodelling? R Gosens, J Zaagsma, MG Bromhaar, A Nelemans, H Meurs European journal of pharmacology 500 (1-3), 193-201, 2004 | 112 | 2004 |
| Muscarinic M3-receptors mediate cholinergic synergism of mitogenesis in airway smooth muscle R Gosens, SA Nelemans, MM Grootte Bromhaar, S McKay, J Zaagsma, ... American journal of respiratory cell and molecular biology 28 (2), 257-262, 2003 | 100 | 2003 |
| Noncanonical WNT-5A signaling regulates TGF-β-induced extracellular matrix production by airway smooth muscle cells K Kumawat, MH Menzen, IST Bos, HA Baarsma, P Borger, M Roth, ... The FASEB journal 27 (4), 1631-1643, 2013 | 93 | 2013 |
| Regulation of airway inflammation and remodeling by muscarinic receptors: perspectives on anticholinergic therapy in asthma and COPD LEM Kistemaker, TA Oenema, H Meurs, R Gosens Life sciences 91 (21-22), 1126-1133, 2012 | 85 | 2012 |
| Allergic sensitization enhances the contribution of Rho‐kinase to airway smooth muscle contraction D Schaafsma, R Gosens, IST Bos, H Meurs, J Zaagsma, SA Nelemans British journal of pharmacology 143 (4), 477-484, 2004 | 85 | 2004 |
| Insulin increases the expression of contractile phenotypic markers in airway smooth muscle D Schaafsma, KD McNeill, GL Stelmack, R Gosens, HA Baarsma, ... American Journal of Physiology-Cell Physiology 293 (1), C429-C439, 2007 | 83 | 2007 |
| Airway smooth muscle phenotype and function: interactions with current asthma therapies AJ Halayko, T Tran, SY Ji, A Yamasaki, R Gosens Current drug targets 7 (5), 525-540, 2006 | 82 | 2006 |
| Muscarinic receptors on airway mesenchymal cells: novel findings for an ancient target H Meurs, BGJ Dekkers, H Maarsingh, AJ Halayko, J Zaagsma, R Gosens Pulmonary pharmacology & therapeutics 26 (1), 145-155, 2013 | 78 | 2013 |