Paul Foster
Paul Foster
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The regulation of steroid action by sulfation and desulfation
JW Mueller, LC Gilligan, J Idkowiak, W Arlt, PA Foster
Endocrine reviews 36 (5), 526-563, 2015
Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment
A Ahluwalia, P Foster, RS Scotland, PG McLean, A Mathur, M Perretti, ...
Proceedings of the National Academy of Sciences 101 (5), 1386-1391, 2004
Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury: novel cardioprotective role for endothelium-derived C-type …
A Hobbs, P Foster, C Prescott, R Scotland, A Ahluwalia
Circulation 110 (10), 1231-1235, 2004
17β‐hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone‐dependent breast cancer
JM Day, PA Foster, HJ Tutill, MFC Parsons, SP Newman, SK Chander, ...
International journal of cancer 122 (9), 1931-1940, 2008
Steroid sulfatase inhibitors for estrogen-and androgen-dependent cancers
A Purohit, PA Foster
Journal of Endocrinology 212 (2), 99-110, 2012
C-type natriuretic peptide inhibits leukocyte recruitment and platelet-leukocyte interactions via suppression of P-selectin expression
RS Scotland, M Cohen, P Foster, M Lovell, A Mathur, A Ahluwalia, ...
Proceedings of the National Academy of Sciences 102 (40), 14452-14457, 2005
Quinazolinone-based anticancer agents: synthesis, antiproliferative SAR, antitubulin activity, and tubulin co-crystal structure
W Dohle, FL Jourdan, G Menchon, AE Prota, PA Foster, P Mannion, ...
Journal of Medicinal Chemistry 61 (3), 1031-1044, 2018
In vivo efficacy of STX213, a second-generation steroid sulfatase inhibitor, for hormone-dependent breast cancer therapy
PA Foster, SP Newman, SK Chander, C Stengel, R Jhalli, LLW Woo, ...
Clinical Cancer Research 12 (18), 5543-5549, 2006
Structure–activity relationships of C-17 cyano-substituted estratrienes as anticancer agents
MP Leese, FL Jourdan, K Gaukroger, MF Mahon, SP Newman, PA Foster, ...
Journal of medicinal chemistry 51 (5), 1295-1308, 2008
Oestrogen and colorectal cancer: mechanisms and controversies
PA Foster
International journal of colorectal disease 28 (6), 737-749, 2013
STX140 is efficacious in vitro and in vivo in taxane-resistant breast carcinoma cells
SP Newman, PA Foster, C Stengel, JM Day, YT Ho, JG Judde, M Lassalle, ...
Clinical Cancer Research 14 (2), 597-606, 2008
The development of steroid sulfatase inhibitors for hormone‐dependent cancer therapy
JM Day, A Purohit, HJ Tutill, PA Foster, LWL Woo, BVL Potter, MJ Reed
Annals of the New York Academy of Sciences 1155 (1), 80-87, 2009
2-Methoxyoestradiol-3,17-O,O-bis-sulphamate and 2-deoxy-D-glucose in combination: a potential treatment for breast and prostate cancer
SLC Tagg, PA Foster, MP Leese, BVL Potter, MJ Reed, A Purohit, ...
British journal of cancer 99 (11), 1842-1848, 2008
In vivo inhibition of angiogenesis by sulphamoylated derivatives of 2-methoxyoestradiol
SK Chander, PA Foster, MP Leese, SP Newman, BVL Potter, A Purohit, ...
British journal of cancer 96 (9), 1368-1376, 2007
Steroid metabolism in breast cancer.
PA Foster
Minerva endocrinologica 33 (1), 27-37, 2008
Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein …
LWL Woo, DS Fischer, CM Sharland, M Trusselle, PA Foster, SK Chander, ...
Molecular cancer therapeutics 7 (8), 2435-2444, 2008
A new therapeutic strategy against hormone-dependent breast cancer: the preclinical development of a dual aromatase and sulfatase inhibitor
PA Foster, SK Chander, SP Newman, LWL Woo, OB Sutcliffe, C Bubert, ...
Clinical Cancer Research 14 (20), 6469-6477, 2008
The use of steroid sulfatase inhibitors as a novel therapeutic strategy against hormone-dependent endometrial cancer
PA Foster, LWL Woo, BVL Potter, MJ Reed, A Purohit
Endocrinology 149 (8), 4035-4042, 2008
NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice
E Meimaridou, M Goldsworthy, V Chortis, E Fragouli, PA Foster, W Arlt, ...
Journal of Endocrinology 236 (1), 13-28, 2018
Efficacy of three potent steroid sulfatase inhibitors: pre-clinical investigations for their use in the treatment of hormone-dependent breast cancer
PA Foster, SK Chander, MFC Parsons, SP Newman, LW Woo, BVL Potter, ...
Breast cancer research and treatment 111 (1), 129-138, 2008
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