| Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies H Yang, S Kurtenbach, Y Guo, I Lohse, MA Durante, J Li, Z Li, H Al-Ali, ... Blood, The Journal of the American Society of Hematology 131 (3), 328-341, 2018 | 155 | 2018 |
| HOTTIP lncRNA promotes hematopoietic stem cell self-renewal leading to AML-like disease in mice H Luo, G Zhu, J Xu, Q Lai, B Yan, Y Guo, TK Fung, BB Zeisig, Y Cui, J Zha, ... Cancer Cell 36 (6), 645-659. e8, 2019 | 135 | 2019 |
| ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis Z Li, P Zhang, A Yan, Z Guo, Y Ban, J Li, S Chen, H Yang, Y He, J Li, ... Science advances 3 (1), e1601602, 2017 | 40 | 2017 |
| CD30L/CD30 is critical for maintenance of IL-17A-producing γδ T cells bearing Vγ6 in mucosa-associated tissues in mice X Sun, K Shibata, H Yamada, Y Guo, H Muta, ER Podack, Y Yoshikai Mucosal immunology 6 (6), 1191-1201, 2013 | 37 | 2013 |
| Loss of ASXL1 in the bone marrow niche dysregulates hematopoietic stem and progenitor cell fates P Zhang, Z Chen, R Li, Y Guo, H Shi, J Bai, H Yang, M Sheng, Z Li, Z Li, ... Cell discovery 4 (1), 1-17, 2018 | 36 | 2018 |
| ASXL1 alteration cooperates with JAK2 V617F to accelerate myelofibrosis Y Guo, Y Zhou, S Yamatomo, H Yang, P Zhang, S Chen, SD Nimer, ... Leukemia 33 (5), 1287-1291, 2019 | 32 | 2019 |
| CD30 is required for activation of a unique subset of interleukin-17A-producing γδ T cells in innate immunity against Mycobacterium bovis Bacillus Calmette-Guerin infection Y Guo, X Sun, K Shibata, H Yamada, H Muta, ER Podack, Y Yoshikai Infection and immunity 81 (10), 3923-3934, 2013 | 31 | 2013 |
| HOXBLINC long non-coding RNA activation promotes leukemogenesis in NPM1-mutant acute myeloid leukemia G Zhu, H Luo, Y Feng, OA Guryanova, J Xu, S Chen, Q Lai, A Sharma, ... Nature Communications 12 (1), 1-17, 2021 | 30 | 2021 |
| Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy P Zhang, F He, J Bai, S Yamamoto, S Chen, L Zhang, M Sheng, L Zhang, ... The Journal of clinical investigation 128 (12), 5383-5398, 2018 | 28 | 2018 |
| Reduced BAP1 activity prevents ASXL1 truncation-driven myeloid malignancy in vivo Y Guo, H Yang, S Chen, P Zhang, R Li, SD Nimer, JW Harbour, M Xu, ... Leukemia 32 (8), 1834-1837, 2018 | 28 | 2018 |
| Loss of Asxl2 leads to myeloid malignancies in mice J Li, F He, P Zhang, S Chen, H Shi, Y Sun, Y Guo, H Yang, N Man, ... Nature communications 8 (1), 1-14, 2017 | 27 | 2017 |
| Innate memory phenotype CD4+ T cells play a role in early protection against infection by Listeria monocytogenes in a CD30L‐dependent manner K Umeda, X Sun, Y Guo, H Yamada, K Shibata, Y Yoshikai Microbiology and immunology 55 (9), 645-656, 2011 | 14 | 2011 |
| The Role of PHF6 in Hematopoiesis and Hematologic Malignancies YA Eisa, Y Guo, FC Yang Stem Cell Reviews and Reports, 1-9, 2022 | 8 | 2022 |
| INTS11 regulates hematopoiesis by promoting PRC2 function P Zhang, P Sui, S Chen, Y Guo, Y Li, G Ge, G Zhu, H Yang, CM Rogers, ... Science Advances 7 (36), eabh1684, 2021 | 6 | 2021 |
| Activation of hottip lncrna perturbs HSC function leading to AML like disease in mice H Luo, G Zhu, J Zha, B Yan, Y Guo, J Xu, Q Lai, B Xu, FC Yang, W Li, ... Blood 132, 3877, 2018 | 4 | 2018 |
| Loss of BRD4 induces cell senescence in HSC/HPCs by deregulating histone H3 clipping H Yang, P Sui, Y Guo, S Chen, ME Maloof, G Ge, F Nihozeko, CR Delma, ... EMBO reports, e57032, 2023 | 2 | 2023 |
| Targeting lysine demethylase 6B ameliorates ASXL1 truncation-mediated myeloid malignancies in preclinical models G Ge, P Zhang, P Sui, S Chen, H Yang, Y Guo, IP Rubalcava, A Noor, ... The Journal of Clinical Investigation, 2023 | 1 | 2023 |
| ASXL2 is required for normal hematopoiesis and loss of asxl2 leads to myeloid malignancies in mice J Li, F He, P Zhang, S Chen, H Shi, Y Sun, G Ying, H Yang, SD Nimer, ... Blood 128 (22), 1509, 2016 | 1 | 2016 |
| SRSF2 mutation cooperates with ASXL1 truncated alteration to accelerate leukemogenesis P Sui, G Ge, S Chen, J Bai, IP Rubalcava, H Yang, Y Guo, P Zhang, Y Li, ... Leukemia, 1-4, 2023 | | 2023 |
| NPM1 mutation mediated HOXBLINC lncRNA activation promotes AML leukemogenesis G Zhu, H Luo, Y Feng, O Guryanova, J Xu, S Chen, Q Lai, B Xu, Z Zhao, ... | | 2020 |
