Nick Barker - Google Scholar Citations

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Hans CleversHubrecht Institute - UtrechtVerified email at hubrecht.eu
Peter J. PetersProfessor of NanoBiology, Maastricht University, The NetherlandsVerified email at maastrichtuniversity.nl
Hugo SnippertUniversity Medical Center Utrecht, The NetherlandsVerified email at umcutrecht.nl
Daniel E StangeUniversität DresdenVerified email at uniklinikum-dresden.de
Pekka KujalaNetherlands Cancer Institute; Hubrecht InstituteVerified email at nki.nl
Pat J MorinExec. Director, Strategic Alliances, Abramson Cancer Center, University of PennsylvaniaVerified email at upenn.edu
Sato ToshiroKeio UniversityVerified email at a7.keio.jp
Bert VogelsteinJohns HopkinsVerified email at jhmi.edu
Kenneth KinzlerJohns Hopkins UniversityVerified email at jhmi.edu
Maria KasperDept of Biosciences and Nutrition, Karolinska InstitutetVerified email at ki.se
Si Hui TanIMB, A*STARVerified email at imb.a-star.edu.sg
Alexander van OudenaardenHubrecht Institute for Developmental Biology and Stem Cell Research, Utrecht, The NetherlandsVerified email at hubrecht.eu
Bon-Kyoung KooIMBA - The Austrian Academy of SciencesVerified email at imba.oeaw.ac.at
Nicholas A WrightProfessor of Histopathology, Queen Mary University of LondonVerified email at qmul.ac.uk
Jacco van RheenenProfessor at the UMC utrecht and group leader Netherlands Cancer InstituteVerified email at nki.nl
Bruno REVERSADEIMB & IMCB, A*STAR, SingaporeVerified email at reversade.com
N. Ray DunnPrincipal Investigator, Institute of Medical BiologyVerified email at imb.a-star.edu.sg
Giulia RancatiPrincipal Investigator, Institute of Medical BiologyVerified email at imb.a-star.edu.sg
Brian BurkeInstitute of Medical Biology, SingaporeVerified email at imb.a-star.edu.sg
Colin L Stewart

Nick Barker

A-STAR Institute of Medical Biology, Singapore

Verified email at imb.a-star.edu.sg

stem cells cancer


Title	Cited by	Year
Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC PJ Morin, AB Sparks, V Korinek, N Barker, H Clevers, B Vogelstein, ... Science 275 (5307), 1787-1790, 1997	4378	1997
Identification of stem cells in small intestine and colon by marker gene Lgr5 N Barker, JH Van Es, J Kuipers, P Kujala, M Van Den Born, M Cozijnsen, ... Nature 449 (7165), 1003, 2007	4013	2007
Constitutive transcriptional activation by a β-catenin-Tcf complex in APC−/− colon carcinoma V Korinek, N Barker, PJ Morin, D Van Wichen, R De Weger, KW Kinzler, ... Science 275 (5307), 1784-1787, 1997	3606	1997
Single Lgr5 stem cells build crypt–villus structures in vitro without a mesenchymal niche T Sato, RG Vries, HJ Snippert, M Van De Wetering, N Barker, DE Stange, ... Nature 459 (7244), 262, 2009	3066	2009
Crypt stem cells as the cells-of-origin of intestinal cancer N Barker, RA Ridgway, JH van Es, M van de Wetering, H Begthel, ... Nature 457 (7229), 608, 2009	1740	2009
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4 V Korinek, N Barker, P Moerer, E van Donselaar, G Huls, PJ Peters, ... Nature genetics 19 (4), 379, 1998	1702	1998
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts T Sato, JH Van Es, HJ Snippert, DE Stange, RG Vries, M Van Den Born, ... Nature 469 (7330), 415, 2011	1582	2011
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells HJ Snippert, LG Van Der Flier, T Sato, JH Van Es, M Van Den Born, ... Cell 143 (1), 134-144, 2010	1269	2010
Lgr5^+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro N Barker, M Huch, P Kujala, M van de Wetering, HJ Snippert, JH van Es, ... Cell stem cell 6 (1), 25-36, 2010	1073	2010
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling W De Lau, N Barker, TY Low, BK Koo, VSW Li, H Teunissen, P Kujala, ... Nature 476 (7360), 293, 2011	934	2011
Mining the Wnt pathway for cancer therapeutics N Barker, H Clevers Nature reviews Drug discovery 5 (12), 997, 2006	858	2006
Lgr5 marks cycling, yet long-lived, hair follicle stem cells V Jaks, N Barker, M Kasper, JH Van Es, HJ Snippert, H Clevers, ... Nature genetics 40 (11), 1291, 2008	847	2008
Functional interaction between ß-catenin and FOXO in oxidative stress signaling MAG Essers, LMM de Vries-Smits, N Barker, PE Polderman, ... Science 308 (5725), 1181-1184, 2005	730	2005
Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties S Schwitalla, AA Fingerle, P Cammareri, T Nebelsiek, SI Göktuna, ... Cell 152 (1-2), 25-38, 2013	714	2013
The TAK1–NLK–MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF T Ishitani, J Ninomiya-Tsuji, S Nagai, M Nishita, M Meneghini, N Barker, ... Nature 399 (6738), 798, 1999	693	1999
Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration N Barker Nature reviews Molecular cell biology 15 (1), 19-33, 2014	647	2014
The intestinal stem cell N Barker, M van de Wetering, H Clevers Genes & development 22 (14), 1856-1864, 2008	634	2008
Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin HJ Snippert, A Haegebarth, M Kasper, V Jaks, JH van Es, N Barker, ... Science 327 (5971), 1385-1389, 2010	621	2010
Transcription factor achaete scute-like 2 controls intestinal stem cell fate LG van der Flier, ME van Gijn, P Hatzis, P Kujala, A Haegebarth, ... Cell 136 (5), 903-912, 2009	599	2009
Organoids as an in vitro model of human development and disease A Fatehullah, SH Tan, N Barker Nature cell biology 18 (3), 246-254, 2016	530	2016

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