Protective role of CXC receptor 4/CXC ligand 12 unveils the importance of neutrophils in atherosclerosis A Zernecke, I Bot, Y Djalali-Talab, E Shagdarsuren, K Bidzhekov, S Meiler, ... Circulation research 102 (2), 209-217, 2008 | 518 | 2008 |
SDF-1α/CXCR4 axis is instrumental in neointimal hyperplasia and recruitment of smooth muscle progenitor cells A Zernecke, A Schober, I Bot, P Von Hundelshausen, EA Liehn, ... Circulation research 96 (7), 784-791, 2005 | 462 | 2005 |
Perivascular mast cells promote atherogenesis and induce plaque destabilization in apolipoprotein E–deficient mice I Bot, SCA de Jager, A Zernecke, KA Lindstedt, TJC van Berkel, C Weber, ... Circulation 115 (19), 2516-2525, 2007 | 369 | 2007 |
Microanatomy of the human atherosclerotic plaque by single-cell transcriptomics MAC Depuydt, KHM Prange, L Slenders, T Örd, D Elbersen, A Boltjes, ... Circulation research 127 (11), 1437-1455, 2020 | 337 | 2020 |
Acute and chronic psychological stress as risk factors for cardiovascular disease: Insights gained from epidemiological, clinical and experimental studies HM Lagraauw, J Kuiper, I Bot Brain, behavior, and immunity 50, 18-30, 2015 | 317 | 2015 |
NLRP3 inflammasome inhibition by MCC950 reduces atherosclerotic lesion development in apolipoprotein E–deficient mice—brief report T van der Heijden, E Kritikou, W Venema, J van Duijn, PJ van Santbrink, ... Arteriosclerosis, thrombosis, and vascular biology 37 (8), 1457-1461, 2017 | 303 | 2017 |
Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis SCA De Jager, B Bermúdez, I Bot, RR Koenen, M Bot, A Kavelaars, ... Journal of Experimental Medicine 208 (2), 217-225, 2011 | 214 | 2011 |
Fibrin and activated platelets cooperatively guide stem cells to a vascular injury and promote differentiation towards an endothelial cell phenotype HC De Boer, C Verseyden, LH Ulfman, JJ Zwaginga, I Bot, EA Biessen, ... Arteriosclerosis, thrombosis, and vascular biology 26 (7), 1653-1659, 2006 | 201 | 2006 |
Mast cells as effectors in atherosclerosis I Bot, GP Shi, PT Kovanen Arteriosclerosis, thrombosis, and vascular biology 35 (2), 265-271, 2015 | 181 | 2015 |
Myocardin regulates vascular smooth muscle cell inflammatory activation and disease M Ackers-Johnson, A Talasila, AP Sage, X Long, I Bot, NW Morrell, ... Arteriosclerosis, thrombosis, and vascular biology 35 (4), 817-828, 2015 | 131 | 2015 |
Differential effects of regulatory T cells on the initiation and regression of atherosclerosis AC Foks, V Frodermann, M Ter Borg, KLL Habets, I Bot, Y Zhao, ... Atherosclerosis 218 (1), 53-60, 2011 | 126 | 2011 |
Y-box binding protein-1 controls CC chemokine ligand-5 (CCL5) expression in smooth muscle cells and contributes to neointima formation in atherosclerosis-prone mice R Krohn, U Raffetseder, I Bot, A Zernecke, E Shagdarsuren, EA Liehn, ... Circulation 116 (16), 1812-1820, 2007 | 125 | 2007 |
Exendin‐4 decreases liver inflammation and atherosclerosis development simultaneously by reducing macrophage infiltration Y Wang, ET Parlevliet, JJ Geerling, SJL Van der Tuin, H Zhang, V Bieghs, ... British journal of pharmacology 171 (3), 723-734, 2014 | 124 | 2014 |
Mast cells in human and experimental cardiometabolic diseases GP Shi, I Bot, PT Kovanen Nature Reviews Cardiology 12 (11), 643-658, 2015 | 122 | 2015 |
Mast cells in human carotid atherosclerotic plaques are associated with intraplaque microvessel density and the occurrence of future cardiovascular events S Willems, A Vink, I Bot, PHA Quax, GJ de Borst, JPPM de Vries, ... European heart journal 34 (48), 3699-3706, 2013 | 118 | 2013 |
Vaccination against Foxp3+ regulatory T cells aggravates atherosclerosis T van Es, GHM van Puijvelde, AC Foks, KLL Habets, I Bot, E Gilboa, ... Atherosclerosis 209 (1), 74-80, 2010 | 112 | 2010 |
Quaking, an RNA-binding protein, is a critical regulator of vascular smooth muscle cell phenotype EP van der Veer, RG de Bruin, AO Kraaijeveld, MR de Vries, I Bot, T Pera, ... Circulation research 113 (9), 1065-1075, 2013 | 107 | 2013 |
The Neuropeptide Substance P Mediates Adventitial Mast Cell Activation and Induces Intraplaque Hemorrhage in Advanced Atherosclerosis I Bot, SCA de Jager, M Bot, SH van Heiningen, P de Groot, ... Circulation research 106, 89-92, 2010 | 100 | 2010 |
Vascular endothelial growth factor-A induces plaque expansion in ApoE knock-out mice by promoting de novo leukocyte recruitment M Lucerna, A Zernecke, R De Nooijer, SC De Jager, I Bot, ... Blood 109 (1), 122-129, 2007 | 100 | 2007 |
Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression RG De Bruin, L Shiue, J Prins, HC De Boer, A Singh, WS Fagg, ... Nature communications 7 (1), 10846, 2016 | 99 | 2016 |