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Aniruddha Jayant Deshpande
Aniruddha Jayant Deshpande
Verified email at sanfordburnham.org
Title
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Cited by
Year
The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice
C Schessl, VPS Rawat, M Cusan, A Deshpande, TM Kohl, PM Rosten, ...
The Journal of clinical investigation 115 (8), 2159-2168, 2005
3012005
DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia
CW Chen, RP Koche, AU Sinha, AJ Deshpande, N Zhu, R Eng, ...
Nature medicine 21 (4), 335-343, 2015
2302015
DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier
MA Santos, RB Faryabi, AV Ergen, AM Day, A Malhowski, A Canela, ...
Nature 514 (7520), 107-111, 2014
2022014
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia
MWM Kühn, E Song, Z Feng, A Sinha, CW Chen, AJ Deshpande, ...
Cancer discovery 6 (10), 1166-1181, 2016
2002016
AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes
AJ Deshpande, A Deshpande, AU Sinha, L Chen, J Chang, A Cihan, ...
Cancer cell 26 (6), 896-908, 2014
1802014
Leukemic transformation by the MLL-AF6 fusion oncogene requires the H3K79 methyltransferase Dot1l
AJ Deshpande, L Chen, M Fazio, AU Sinha, KM Bernt, D Banka, S Dias, ...
Blood, The Journal of the American Society of Hematology 121 (13), 2533-2541, 2013
1762013
Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia
AJ Deshpande, M Cusan, VPS Rawat, H Reuter, A Krause, C Pott, ...
Cancer cell 10 (5), 363-374, 2006
1542006
A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis
K Petropoulos, N Arseni, C Schessl, CR Stadler, VPS Rawat, ...
The Journal of experimental medicine 205 (3), 515-522, 2008
1522008
Abrogation of MLL–AF10 and CALM–AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l
L Chen, AJ Deshpande, D Banka, KM Bernt, S Dias, C Buske, EJ Olhava, ...
Leukemia 27 (4), 813-822, 2013
1472013
Ectopic expression of the homeobox gene Cdx2 is the transforming event in a mouse model of t (12; 13)(p13; q12) acute myeloid leukemia
VPS Rawat, M Cusan, A Deshpande, W Hiddemann, ...
Proceedings of the National Academy of Sciences 101 (3), 817-822, 2004
1342004
A multiscale map of the stem cell state in pancreatic adenocarcinoma
NK Lytle, LP Ferguson, N Rajbhandari, K Gilroy, RG Fox, A Deshpande, ...
Cell 177 (3), 572-586. e22, 2019
1282019
3’UTR mediated regulation of the cyclin D1 proto-oncogene
A Deshpande, A Pastore, AJ Deshpande, Y Zimmermann, G Hutter, ...
Cell Cycle 8 (21), 3592-3600, 2009
1142009
The role of TP53 in acute myeloid leukemia: challenges and opportunities
K Barbosa, S Li, PD Adams, AJ Deshpande
Genes, Chromosomes and Cancer 58 (12), 875-888, 2019
1032019
MLL-AF9–and HOXA9-mediated acute myeloid leukemia stem cell self-renewal requires JMJD1C
N Zhu, M Chen, R Eng, J DeJong, AU Sinha, NF Rahnamay, R Koche, ...
The Journal of clinical investigation 126 (3), 997-1011, 2016
1032016
Overexpression of CDX2 perturbs HOX gene expression in murine progenitors depending on its N-terminal domain and is closely correlated with deregulated HOX gene expression in …
VPS Rawat, S Thoene, VM Naidu, N Arseni, B Heilmeier, K Metzeler, ...
Blood, The Journal of the American Society of Hematology 111 (1), 309-319, 2008
932008
The PZP domain of AF10 senses unmodified H3K27 to regulate DOT1L-mediated methylation of H3K79
S Chen, Z Yang, AW Wilkinson, AJ Deshpande, S Sidoli, K Krajewski, ...
Molecular cell 60 (2), 319-327, 2015
912015
Loss of HIF1A from pancreatic cancer cells increases expression of PPP1R1B and degradation of p53 to promote invasion and metastasis
A Tiwari, K Tashiro, A Dixit, A Soni, K Vogel, B Hall, I Shafqat, J Slaughter, ...
Gastroenterology 159 (5), 1882-1897. e5, 2020
842020
Epigenetic regulators in the development, maintenance, and therapeutic targeting of acute myeloid leukemia
Y Sun, BR Chen, A Deshpande
Frontiers in oncology 8, 41, 2018
672018
Chromatin modifications as therapeutic targets in MLL-rearranged leukemia
AJ Deshpande, J Bradner, SA Armstrong
Trends in immunology 33 (11), 563-570, 2012
672012
Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10–positive leukemias
YH Lin, PM Kakadia, Y Chen, YQ Li, AJ Deshpande, C Buske, KL Zhang, ...
Blood, The Journal of the American Society of Hematology 114 (3), 651-658, 2009
672009
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