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Peter A.C. 't Hoen
Peter A.C. 't Hoen
Professor Bioinformatics, Centre for Molecular and Biomolecular Informatics, Radboudumc Nijmegen
Geverifieerd e-mailadres voor radboudumc.nl - Homepage
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The FAIR Guiding Principles for scientific data management and stewardship
Scientific Data 3, 160018, 2016
8353*2016
Transcriptome and genome sequencing uncovers functional variation in humans
T Lappalainen, M Sammeth, MR Friedländer, PAC t Hoen, J Monlong, ...
Nature 501 (7468), 506-511, 2013
18382013
Systematic identification of trans eQTLs as putative drivers of known disease associations
HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ...
Nature genetics 45 (10), 1238-1243, 2013
17232013
A promoter-level mammalian expression atlas
Nature 507 (7493), 462-470, 2014
14982014
Deep sequencing-based expression analysis shows major advances in robustness, resolution and inter-lab portability over five microarray platforms
PAC 't Hoen, Y Ariyurek, HH Thygesen, E Vreugdenhil, RHAM Vossen, ...
Nucleic acids research 36 (21), e141-e141, 2008
7762008
Gateways to the FANTOM5 promoter level mammalian expression atlas
M Lizio, J Harshbarger, H Shimoji, J Severin, T Kasukawa, S Sahin, ...
Genome biology 16 (1), 1-14, 2015
6882015
Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions
ENM Nolte-’t Hoen, HPJ Buermans, M Waasdorp, W Stoorvogel, ...
Nucleic acids research 40 (18), 9272-9285, 2012
5052012
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
LV Wain, GC Verwoert, PF O'Reilly, G Shi, T Johnson, AD Johnson, ...
Nature genetics 43 (10), 1005-1011, 2011
4602011
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis
U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
BioRxiv, 447367, 2018
4282018
Disease variants alter transcription factor levels and methylation of their binding sites
MJ Bonder, R Luijk, DV Zhernakova, M Moed, P Deelen, M Vermaat, ...
Nature genetics 49 (1), 131-138, 2017
3672017
Identification of context-dependent expression quantitative trait loci in whole blood
DV Zhernakova, P Deelen, M Vermaat, M Van Iterson, M Van Galen, ...
Nature genetics 49 (1), 139-145, 2017
3532017
Alternative mRNA transcription, processing, and translation: insights from RNA sequencing
E de Klerk, P AC‘t Hoen
Trends in Genetics 31 (3), 128-139, 2015
3482015
Genetic and environmental influences interact with age and sex in shaping the human methylome
J Van Dongen, MG Nivard, G Willemsen, JJ Hottenga, Q Helmer, ...
Nature communications 7 (1), 1-13, 2016
2842016
Effect of predicted protein-truncating genetic variants on the human transcriptome
MA Rivas, M Pirinen, DF Conrad, M Lek, EK Tsang, KJ Karczewski, ...
Science 348 (6235), 666-669, 2015
2722015
Prorenin induces intracellular signaling in cardiomyocytes independently of angiotensin II
JJ Saris, PAC ’t Hoen, IM Garrelds, DHW Dekkers, JT den Dunnen, ...
Hypertension 48 (4), 564-571, 2006
2622006
Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories
PAC t Hoen, MR Friedländer, J Almlöf, M Sammeth, I Pulyakhina, ...
Nature biotechnology 31 (11), 1015-1022, 2013
2382013
Guidelines for antisense oligonucleotide design and insight into splice-modulating mechanisms
A Aartsma-Rus, L Van Vliet, M Hirschi, AAM Janson, H Heemskerk, ...
Molecular Therapy 17 (3), 548-553, 2009
2232009
Large-scale cis-and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
Nature genetics 53 (9), 1300-1310, 2021
2072021
Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer
M Van den Boogaard, LYE Wong, F Tessadori, ML Bakker, ...
The Journal of clinical investigation 122 (7), 2519-2530, 2012
1952012
The FAIR Guiding Principles for scientific data management and stewardship. Sci Data 3: 160018
MD Wilkinson, M Dumontier, IJ Aalbersberg, G Appleton, M Axton, A Baak, ...
1942016
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Artikelen 1–20