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Jacob F. Kocher
Jacob F. Kocher
Senior Principal Scientist
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Year
High dose and low dose Lactobacillus acidophilus exerted differential immune modulating effects on T cell immune responses induced by an oral human rotavirus vaccine in …
K Wen, G Li, T Bui, F Liu, Y Li, J Kocher, L Lin, X Yang, L Yuan
Vaccine 30 (6), 1198-1207, 2012
1282012
MERS-CoV accessory ORFs play key role for infection and pathogenesis
VD Menachery, HD Mitchell, AS Cockrell, LE Gralinski, BL Yount Jr, ...
MBio 8 (4), e00665-17, 2017
1162017
Probiotic Lactobacillus rhamnosus GG enhanced Th1 cellular immunity but did not affect antibody responses in a human gut microbiota transplanted neonatal gnotobiotic pig model
K Wen, C Tin, H Wang, X Yang, G Li, E Giri-Rachman, J Kocher, T Bui, ...
PloS one 9 (4), e94504, 2014
732014
Allelic Variation in the Toll-Like Receptor Adaptor Protein Ticam2 Contributes to SARS-Coronavirus Pathogenesis in Mice
LE Gralinski, VD Menachery, AP Morgan, AL Totura, A Beall, J Kocher, ...
G3: Genes, Genomes, Genetics 7 (6), 1653-1663, 2017
712017
High protective efficacy of rice bran against human rotavirus diarrhea via enhancing probiotic growth, gut barrier function and innate immunity
X Yang, E Twitchell, G Li, K Wen, M Weiss, J Kocher, S Lei, A Ramesh, ...
Scientific reports 5 (1), 1-12, 2015
682015
Lactobacillus rhamnosus GG on rotavirus induced injury of ileal epithelium in gnotobiotic pigs
F Liu, G Li, K Wen, S Wu, Y Zhang, T Bui, X Yang, J Kocher, J Sun, ...
Journal of pediatric gastroenterology and nutrition 57 (6), 2013
622013
Probiotics and virulent human rotavirus modulate the transplanted human gut microbiota in gnotobiotic pigs
H Zhang, H Wang, M Shepherd, K Wen, G Li, X Yang, J Kocher, ...
Gut pathogens 6 (1), 39, 2014
612014
High protective efficacy of probiotics and rice bran against human norovirus infection and diarrhea in gnotobiotic pigs
S Lei, A Ramesh, E Twitchell, K Wen, T Bui, M Weiss, X Yang, J Kocher, ...
Frontiers in microbiology 7, 1699, 2016
542016
Intranasal P particle vaccine provided partial cross-variant protection against human GII. 4 norovirus diarrhea in gnotobiotic pigs
J Kocher, T Bui, E Giri-Rachman, K Wen, G Li, X Yang, F Liu, M Tan, ...
Journal of virology 88 (17), 9728-9743, 2014
532014
Median infectious dose of human norovirus GII. 4 in gnotobiotic pigs is decreased by simvastatin treatment and increased by age
T Bui, J Kocher, Y Li, K Wen, G Li, F Liu, X Yang, T LeRoith, M Tan, M Xia, ...
The Journal of general virology 94 (Pt 9), 2005, 2013
512013
Lactobacillus rhamnosus GG modulates innate signaling pathway and cytokine responses to rotavirus vaccine in intestinal mononuclear cells of gnotobiotic pigs transplanted with …
H Wang, K Gao, K Wen, IC Allen, G Li, W Zhang, J Kocher, X Yang, ...
BMC microbiology 16 (1), 109, 2016
452016
Adaptive evolution influences the infectious dose of MERS-CoV necessary to achieve severe respiratory disease
MG Douglas, JF Kocher, T Scobey, RS Baric, AS Cockrell
Virology 517, 98-107, 2018
442018
Lactobacillus rhamnosus GG dosage affects the adjuvanticity and protection against rotavirus diarrhea in gnotobiotic pigs
K Wen, F Liu, G Li, M Bai, J Kocher, X Yang, H Wang, S Clark-Deener, ...
Journal of pediatric gastroenterology and nutrition 60 (6), 834-843, 2015
442015
Dietary rice bran protects against rotavirus diarrhea and promotes Th1-type immune responses to human rotavirus vaccine in gnotobiotic pigs
X Yang, K Wen, C Tin, G Li, H Wang, J Kocher, K Pelzer, E Ryan, L Yuan
Clinical and Vaccine Immunology 21 (10), 1396-1403, 2014
432014
Norovirus vaccines and potential antinorovirus drugs: recent advances and future perspectives
J Kocher, L Yuan
Future virology 10 (7), 899-913, 2015
382015
Probiotic Lactobacillus rhamnosus GG mono-association suppresses human rotavirus-induced autophagy in the gnotobiotic piglet intestine
S Wu, L Yuan, Y Zhang, F Liu, G Li, K Wen, J Kocher, X Yang, J Sun
Gut pathogens 5 (1), 22, 2013
372013
Dual functions of Lactobacillus acidophilus NCFM™ at the intermediate dose in protection against rotavirus diarrhea in gnotobiotic pigs vaccinated with a human rotavirus vaccine
F Liu, K Wen, G Li, X Yang, J Kocher, T Bui, D Jones, K Pelzer, ...
Journal of pediatric gastroenterology and nutrition 58 (2), 171, 2014
362014
Characterization of immune modulating functions of γδ T cell subsets in a gnotobiotic pig model of human rotavirus infection
K Wen, T Bui, G Li, F Liu, Y Li, J Kocher, L Yuan
Comparative immunology, microbiology and infectious diseases 35 (4), 289-301, 2012
362012
Emergence of novel human norovirus GII. 17 strains correlates with changes in blockade antibody epitopes
LC Lindesmith, JF Kocher, EF Donaldson, K Debbink, ML Mallory, ...
The Journal of Infectious Diseases 216 (10), 1227-1234, 2017
262017
CD4+ CD25 FoxP3+ regulatory cells are the predominant responding regulatory T cells after human rotavirus infection or vaccination in gnotobiotic pigs
K Wen, G Li, X Yang, T Bui, M Bai, F Liu, J Kocher, L Yuan
Immunology 137 (2), 160-171, 2012
232012
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