Johann de Jong
Johann de Jong
Principal Scientist, Boehringer Ingelheim
Verified email at - Homepage
Cited by
Cited by
Chromatin position effects assayed by thousands of reporters integrated in parallel
W Akhtar, J de Jong, AV Pindyurin, L Pagie, W Meuleman, J de Ridder, ...
Cell 154 (4), 914-927, 2013
Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model
EA Bard-Chapeau, AT Nguyen, AG Rust, A Sayadi, P Lee, BQ Chua, ...
Nature genetics 46 (1), 24-32, 2014
Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function
MR Heideman, RH Wilting, E Yanover, A Velds, J de Jong, RM Kerkhoven, ...
Blood, The Journal of the American Society of Hematology 121 (11), 2038-2050, 2013
Chromatin landscapes of retroviral and transposon integration profiles
J de Jong, W Akhtar, J Badhai, AG Rust, R Rad, J Hilkens, A Berns, ...
PLoS genetics 10 (4), e1004250, 2014
Prolonged Ezh2 depletion in glioblastoma causes a robust switch in cell fate resulting in tumor progression
NA de Vries, D Hulsman, W Akhtar, J de Jong, DC Miles, M Blom, ...
Cell reports 10 (3), 383-397, 2015
A cell-based model of Nematostella vectensis gastrulation including bottle cell formation, invagination and zippering
C Tamulonis, M Postma, HQ Marlow, CR Magie, J de Jong, J Kaandorp
Developmental biology 351 (1), 217-228, 2011
Chemical profiling of the genome with anti-cancer drugs defines target specificities
B Pang, J De Jong, X Qiao, LFA Wessels, J Neefjes
Nature chemical biology 11 (7), 472-480, 2015
Computational identification of insertional mutagenesis targets for cancer gene discovery
J de Jong, J de Ridder, L van der Weyden, N Sun, M van Uitert, A Berns, ...
Nucleic acids research 39 (15), e105-e105, 2011
3D hotspots of recurrent retroviral insertions reveal long-range interactions with cancer genes
S Babaei, W Akhtar, J De Jong, M Reinders, J De Ridder
Nature communications 6 (1), 1-10, 2015
Multiplexed Cas9 targeting reveals genomic location effects and gRNA-based staggered breaks influencing mutation efficiency
S Gisler, JP Gonçalves, W Akhtar, J de Jong, AV Pindyurin, LFA Wessels, ...
Nature communications 10 (1), 1-14, 2019
Using TRIP for genome-wide position effect analysis in cultured cells
W Akhtar, AV Pindyurin, J De Jong, L Pagie, J Ten Hoeve, A Berns, ...
Nature protocols 9 (6), 1255-1281, 2014
A computational approach towards a gene regulatory network for the developing Nematostella vectensis gut
D Botman, E Röttinger, MQ Martindale, J de Jong, JA Kaandorp
PLoS One 9 (7), e103341, 2014
The small FOXP1 isoform predominantly expressed in activated B cell-like diffuse large B-cell lymphoma and full-length FOXP1 exert similar oncogenic and transcriptional …
M van Keimpema, LJ Grüneberg, EJM Schilder-Tol, MECM Oud, ...
Haematologica 102 (3), 573, 2017
Deep learning for clustering of multivariate clinical patient trajectories with missing values
J de Jong, MA Emon, P Wu, R Karki, M Sood, P Godard, A Ahmad, ...
GigaScience 8 (11), giz134, 2019
Analysis of a spatial gene expression database for sea anemone Nematostella vectensis during early development
D Botman, F Jansson, E Röttinger, MQ Martindale, J De Jong, ...
BMC systems biology 9 (1), 1-21, 2015
TRIP through the chromatin: a high throughput exploration of enhancer regulatory landscapes
AV Pindyurin, J de Jong, W Akhtar
Genomics 106 (3), 171-177, 2015
Towards realizing the vision of precision medicine: AI based prediction of clinical drug response
J de Jong, I Cutcutache, M Page, S Elmoufti, C Dilley, H Fröhlich, ...
Brain, 2021
Applications of DNA integrating elements: Facing the bias bully
J de Jong, LFA Wessels, M van Lohuizen, J de Ridder, W Akhtar
Mobile genetic elements 4 (6), 1-6, 2014
Mutational genomics for cancer pathway discovery
J de Ridder, J Kool, AG Uren, J Bot, J de Jong, AG Rust, A Berns, ...
IAPR International Conference on Pattern Recognition in Bioinformatics, 35-46, 2013
An Explainable Multimodal Neural Network Architecture for Predicting Epilepsy Comorbidities Based on Administrative Claims Data
T Linden, J De Jong, C Lu, V Kiri, K Haeffs, H Fröhlich
Frontiers in artificial intelligence 4, 2021
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Articles 1–20