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Isidro Cortés Ciriano
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The repertoire of mutational signatures in human cancer
LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AW Tian Ng, Y Wu, ...
Nature 578 (7793), 94-101, 2020
23382020
Comprehensive characterization of cancer driver genes and mutations
MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ...
Cell 173 (2), 371-385. e18, 2018
21052018
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
1671*2020
Patterns of somatic structural variation in human cancer genomes
Y Li, ND Roberts, JA Wala, O Shapira, SE Schumacher, K Kumar, ...
Nature 578 (7793), 112-121, 2020
6762020
A molecular portrait of microsatellite instability across multiple cancers
I Cortes-Ciriano, S Lee, WY Park, TM Kim, PJ Park
Nature communications 8 (1), 15180, 2017
5512017
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
I Cortes-Ciriano, JK Lee, R Xi, D Jain, YL Jung, L Yang, D Gordenin, ...
Nature Genetics 52, 331–341, 2020
5262020
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
E Rheinbay, MM Nielsen, F Abascal, JA Wala, O Shapira, G Tiao, ...
Nature 578 (7793), 102-111, 2020
4972020
Mechanisms and therapeutic implications of hypermutation in gliomas
M Touat, YY Li, AN Boynton, LF Spurr, JB Iorgulescu, CL Bohrson, ...
Nature 580 (7804), 517-523, 2020
4372020
Perspective on oncogenic processes at the end of the beginning of cancer genomics
L Ding, MH Bailey, E Porta-Pardo, V Thorsson, A Colaprico, D Bertrand, ...
Cell 173 (2), 305-320. e10, 2018
3492018
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
B Rodriguez-Martin, EG Alvarez, A Baez-Ortega, J Zamora, F Supek, ...
Nature genetics 52 (3), 306-319, 2020
3252020
The landscape of viral associations in human cancers
M Zapatka, I Borozan, DS Brewer, M Iskar, A Grundhoff, M Alawi, N Desai, ...
Nature genetics 52 (3), 320-330, 2020
3182020
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
MP Menden, D Wang, MJ Mason, B Szalai, KC Bulusu, Y Guan, T Yu, ...
Nature communications 10 (1), 2674, 2019
301*2019
Genomic basis for RNA alterations in cancer
PCAWG Transcriptome Core Group Calabrese Claudia 2 Davidson Natalie R. 3 4 5 ...
Nature 578 (7793), 129-136, 2020
2712020
Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network
MJ McConnell, JV Moran, A Abyzov, S Akbarian, T Bae, I Cortes-Ciriano, ...
Science 356 (6336), eaal1641, 2017
2442017
Detecting the mutational signature of homologous recombination deficiency in clinical samples
DC Gulhan, JJK Lee, GEM Melloni, I Cortes-Ciriano, PJ Park
Nature genetics 51 (5), 912-919, 2019
2402019
Artificial intelligence in drug discovery: what is realistic, what are illusions? Part 1: Ways to make an impact, and why we are not there yet
A Bender, I Cortés-Ciriano
Drug discovery today 26 (2), 511-524, 2021
2052021
Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer
KC Akdemir, VT Le, S Chandran, Y Li, RG Verhaak, R Beroukhim, ...
Nature genetics 52 (3), 294-305, 2020
1922020
A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns
W Jiao, G Atwal, P Polak, R Karlic, E Cuppen, A Danyi, J de Ridder, ...
Nature communications 11 (1), 728, 2020
1692020
Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis
J Carlevaro-Fita, A Lanzós, L Feuerbach, C Hong, D Mas-Ponte, ...
Communications biology 3 (1), 56, 2020
1592020
Reconstructing the lineage histories and differentiation trajectories of individual cancer cells in myeloproliferative neoplasms
D Van Egeren, J Escabi, M Nguyen, S Liu, CR Reilly, S Patel, B Kamaz, ...
Cell stem cell 28 (3), 514-523. e9, 2021
1512021
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