Thomas Look
Thomas Look
Professor of Pediatrics, Harvard Medical School
Adresse e-mail validée de dfci.harvard.edu - Page d'accueil
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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
AP Weng, AA Ferrando, W Lee, JP Morris, LB Silverman, ...
Science 306 (5694), 269-271, 2004
29362004
Acute lymphoblastic leukemia
CH Pui, MV Relling, JR Downing
New England Journal of Medicine 350 (15), 1535-1548, 2004
28282004
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
SW Morris, MN Kirstein, MB Valentine, KG Dittmer, DN Shapiro, ...
Science 263 (5151), 1281-1284, 1994
24161994
Acute lymphoblastic leukaemia
CH Pui, LL Robison, AT Look
The Lancet 371 (9617), 1030-1043, 2008
18222008
The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1
CJ Sherr, CW Rettenmier, R Sacca, MF Roussel, AT Look, ER Stanley
Cell 41 (3), 665-676, 1985
18001985
Oncogenic transcription factors in the human acute leukemias
AT Look
Science 278 (5340), 1059-1064, 1997
14311997
A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish
P Niethammer, C Grabher, AT Look, TJ Mitchison
Nature 459 (7249), 996-999, 2009
13762009
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
AA Ferrando, DS Neuberg, J Staunton, ML Loh, C Huard, SC Raimondi, ...
Cancer cell 1 (1), 75-87, 2002
11812002
Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN
T Teitz, T Wei, MB Valentine, EF Vanin, J Grenet, VA Valentine, FG Behm, ...
Nature medicine 6 (5), 529-535, 2000
9392000
Human aminopeptidase N is a receptor for human coronavirus 229E
CL Yeager, RA Ashmun, RK Williams, CB Cardellichio, LH Shapiro, ...
Nature 357 (6377), 420-422, 1992
8981992
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
T Palomero, WK Lim, DT Odom, ML Sulis, PJ Real, A Margolin, ...
Proceedings of the National Academy of Sciences 103 (48), 18261-18266, 2006
8792006
Hematology of infancy and childhood
DG Nathan, FA Oski
WB Saunders Co., Philadelphia, PA, 1987
8501987
Activating mutations in ALK provide a therapeutic target in neuroblastoma
RE George, T Sanda, M Hanna, S Fröhling, W Luther II, J Zhang, Y Ahn, ...
Nature 455 (7215), 975-978, 2008
8482008
Identification of breakpoints in t (8; 21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt
P Erickson, J Gao, KS Chang, T Look, E Whisenant, S Raimondi, ...
7211992
Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study.
AT Look, FA Hayes, JJ Shuster, EC Douglass, RP Castleberry, ...
Journal of Clinical Oncology 9 (4), 581-591, 1991
6841991
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors
J O'Neil, J Grim, P Strack, S Rao, D Tibbitts, C Winter, J Hardwick, ...
The Journal of experimental medicine 204 (8), 1813-1824, 2007
6792007
BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma
EE Patton, HR Widlund, JL Kutok, KR Kopani, JF Amatruda, RD Murphey, ...
Current Biology 15 (3), 249-254, 2005
6452005
Chromosome 1p and 11q deletions and outcome in neuroblastoma
EF Attiyeh, WB London, YP Mossé, Q Wang, C Winter, D Khazi, ...
New England Journal of Medicine 353 (21), 2243-2253, 2005
5962005
The use of zebrafish to understand immunity
NS Trede, DM Langenau, D Traver, AT Look, LI Zon
Immunity 20 (4), 367-379, 2004
5882004
The retinoblastoma protein binds to a family of E2F transcription factors
JA Lees, M Saito, M Vidal, M Valentine, T Look, E Harlow, N Dyson, ...
Molecular and cellular biology 13 (12), 7813-7825, 1993
5881993
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