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Jennifer M. Giltnane, MD, PhD
Jennifer M. Giltnane, MD, PhD
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TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
S Mariathasan, SJ Turley, D Nickles, A Castiglioni, K Yuen, Y Wang, ...
Nature 554 (7693), 544-548, 2018
38752018
Assessing tumor-infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the International Immuno-Oncology …
S Hendry, R Salgado, T Gevaert, PA Russell, T John, B Thapa, M Christie, ...
Advances in anatomic pathology 24 (6), 311-335, 2017
6992017
Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor–positive breast cancer
R Jeselsohn, R Yelensky, G Buchwalter, G Frampton, F Meric-Bernstam, ...
Clinical cancer research 20 (7), 1757-1767, 2014
6892014
Assessing tumor-infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the international immunooncology …
S Hendry, R Salgado, T Gevaert, PA Russell, T John, B Thapa, M Christie, ...
Advances in anatomic pathology 24 (5), 235-251, 2017
6302017
Molecular profiling of the residual disease of triple-negative breast cancers after neoadjuvant chemotherapy identifies actionable therapeutic targets
JM Balko, JM Giltnane, K Wang, LJ Schwarz, CD Young, RS Cook, ...
Cancer discovery 4 (2), 232-245, 2014
5492014
RAS/MAPK activation is associated with reduced tumor-infiltrating lymphocytes in triple-negative breast cancer: therapeutic cooperation between MEK and PD-1/PD-L1 immune …
S Loi, S Dushyanthen, PA Beavis, R Salgado, C Denkert, P Savas, ...
Clinical Cancer Research 22 (6), 1499-1509, 2016
5382016
MYC and MCL1 cooperatively promote chemotherapy-resistant breast cancer stem cells via regulation of mitochondrial oxidative phosphorylation
K Lee, JM Giltnane, JM Balko, LJ Schwarz, AL Guerrero-Zotano, ...
Cell metabolism 26 (4), 633-647. e7, 2017
5282017
High HSP90 expression is associated with decreased survival in breast cancer
E Pick, Y Kluger, JM Giltnane, C Moeder, RL Camp, DL Rimm, HM Kluger
Cancer research 67 (7), 2932-2937, 2007
4452007
Single-cell dynamics determines response to CDK4/6 inhibition in triple-negative breast cancer
US Asghar, AR Barr, R Cutts, M Beaney, I Babina, D Sampath, J Giltnane, ...
Clinical Cancer Research 23 (18), 5561-5572, 2017
2432017
Quantitative in situ analysis of β-catenin expression in breast cancer shows decreased expression is associated with poor outcome
M Dolled-Filhart, A McCabe, J Giltnane, M Cregger, RL Camp, DL Rimm
Cancer research 66 (10), 5487-5494, 2006
2122006
Intratumoral plasma cells predict outcomes to PD-L1 blockade in non-small cell lung cancer
NS Patil, BY Nabet, S Müller, H Koeppen, W Zou, J Giltnane, A Au-Yeung, ...
Cancer cell 40 (3), 289-300. e4, 2022
1962022
Rationale for targeting the Ras/MAPK pathway in triple-negative breast cancer
JM Giltnane, JM Balko
Discovery medicine 17 (95), 275-283, 2014
1882014
Single-cell dissection of cellular components and interactions shaping the tumor immune phenotypes in ovarian cancer
M Hornburg, M Desbois, S Lu, Y Guan, AA Lo, S Kaufman, A Elrod, ...
Cancer cell 39 (7), 928-944. e6, 2021
1872021
Therapeutic ligands antagonize estrogen receptor function by impairing its mobility
J Guan, W Zhou, M Hafner, RA Blake, C Chalouni, IP Chen, T De Bruyn, ...
Cell 178 (4), 949-963. e18, 2019
1592019
Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence
JM Balko, LJ Schwarz, N Luo, MV Estrada, JM Giltnane, ...
Science translational medicine 8 (334), 334ra53-334ra53, 2016
1452016
Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer
Z Kos, E Roblin, RS Kim, S Michiels, BD Gallas, W Chen, KK van de Vijver, ...
NPJ breast cancer 6 (1), 17, 2020
1372020
The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer
JD Joseph, B Darimont, W Zhou, A Arrazate, A Young, E Ingalla, K Walter, ...
Elife 5, e15828, 2016
1312016
Association of FGFR1 with ERα maintains ligand-independent ER transcription and mediates resistance to estrogen deprivation in ER+ breast cancer
L Formisano, KM Stauffer, CD Young, NE Bhola, AL Guerrero-Zotano, ...
Clinical Cancer Research 23 (20), 6138-6150, 2017
1292017
Report on computational assessment of tumor infiltrating lymphocytes from the International Immuno-Oncology Biomarker Working Group
M Amgad, ES Stovgaard, E Balslev, J Thagaard, W Chen, S Dudgeon, ...
NPJ breast cancer 6 (1), 16, 2020
1262020
Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance
JM Giltnane, KE Hutchinson, TP Stricker, L Formisano, CD Young, ...
Science translational medicine 9 (402), eaai7993, 2017
1222017
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