| Prospective derivation of a living organoid biobank of colorectal cancer patients M Van de Wetering, HE Francies, JM Francis, G Bounova, F Iorio, A Pronk, ... Cell 161 (4), 933-945, 2015 | 2059 | 2015 |
| Single-cell messenger RNA sequencing reveals rare intestinal cell types D Grün, A Lyubimova, L Kester, K Wiebrands, O Basak, N Sasaki, ... Nature 525 (7568), 251-255, 2015 | 1256 | 2015 |
| Validation of noise models for single-cell transcriptomics D Grün, L Kester, A Van Oudenaarden Nature methods 11 (6), 637-640, 2014 | 761 | 2014 |
| An organoid platform for ovarian cancer captures intra-and interpatient heterogeneity O Kopper, CJ De Witte, K Lõhmussaar, JE Valle-Inclan, N Hami, L Kester, ... Nature medicine 25 (5), 838-849, 2019 | 583 | 2019 |
| Integrated genome and transcriptome sequencing of the same cell SS Dey, L Kester, B Spanjaard, M Bienko, A Van Oudenaarden Nature biotechnology 33 (3), 285-289, 2015 | 513 | 2015 |
| Single-cell transcriptomics meets lineage tracing L Kester, A Van Oudenaarden Cell stem cell 23 (2), 166-179, 2018 | 358 | 2018 |
| Plasticity between epithelial and mesenchymal states unlinks EMT from metastasis-enhancing stem cell capacity E Beerling, D Seinstra, E de Wit, L Kester, D van der Velden, C Maynard, ... Cell reports 14 (10), 2281-2288, 2016 | 338 | 2016 |
| Differential proliferation rates generate patterns of mechanical tension that orient tissue growth Y Mao, AL Tournier, A Hoppe, L Kester, BJ Thompson, N Tapon The EMBO journal 32 (21), 2790-2803, 2013 | 319 | 2013 |
| Plasticity of Lgr5-negative cancer cells drives metastasis in colorectal cancer A Fumagalli, KC Oost, L Kester, J Morgner, L Bornes, L Bruens, ... Cell stem cell 26 (4), 569-578. e7, 2020 | 221 | 2020 |
| Expansion of adult human pancreatic tissue yields organoids harboring progenitor cells with endocrine differentiation potential CJM Loomans, NW Giuliani, J Balak, F Ringnalda, L van Gurp, M Huch, ... Stem Cell Reports 10 (3), 712-724, 2018 | 122 | 2018 |
| Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2 S Simmini, M Bialecka, M Huch, L Kester, M Van De Wetering, T Sato, ... Nature communications 5 (1), 5728, 2014 | 119 | 2014 |
| Cdx and T brachyury co-activate growth signaling in the embryonic axial progenitor niche S Amin, R Neijts, S Simmini, C van Rooijen, SC Tan, L Kester, ... Cell reports 17 (12), 3165-3177, 2016 | 112 | 2016 |
| Single-cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta CS Baron, L Kester, A Klaus, JC Boisset, R Thambyrajah, L Yvernogeau, ... Nature communications 9 (1), 2517, 2018 | 111 | 2018 |
| DAZL regulates Tet1 translation in murine embryonic stem cells M Welling, HH Chen, J Muñoz, MU Musheev, L Kester, JP Junker, ... EMBO reports 16 (7), 791-802, 2015 | 28 | 2015 |
| Ultra-fast deep-learned CNS tumour classification during surgery C Vermeulen, M Pagès-Gallego, L Kester, MEG Kranendonk, ... Nature 622 (7984), 842-849, 2023 | 27 | 2023 |
| CCN2 aggravates the immediate oxidative stress–DNA damage response following renal ischemia–reperfusion injury FA Valentijn, SN Knoppert, G Pissas, RR Rodrigues-Diez, ... Antioxidants 10 (12), 2020, 2021 | 23 | 2021 |
| Implementation of paediatric precision oncology into clinical practice: The Individualized Therapies for Children with cancer program ‘iTHER’ KPS Langenberg, MT Meister, JJ Bakhuizen, JM Boer, ... European Journal of Cancer 175, 311-325, 2022 | 16 | 2022 |
| Improved gene fusion detection in childhood cancer diagnostics using RNA sequencing JY Hehir-Kwa, MJ Koudijs, ETP Verwiel, LA Kester, M van Tuil, ... JCO precision oncology 6, e2000504, 2022 | 16 | 2022 |
| Integration of multiple lineage measurements from the same cell reconstructs parallel tumor evolution L Kester, B de Barbanson, A Lyubimova, LT Chen, V van der Schrier, ... Cell Genomics 2 (2), 2022 | 15 | 2022 |
| Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS IAEM van Belzen, C Cai, M van Tuil, S Badloe, E Strengman, A Janse, ... BMC cancer 23 (1), 618, 2023 | 11 | 2023 |
