A novel antifibrotic mechanism of nintedanib and pirfenidone. Inhibition of collagen fibril assembly L Knüppel, Y Ishikawa, M Aichler, K Heinzelmann, R Hatz, J Behr, ... American journal of respiratory cell and molecular biology 57 (1), 77-90, 2017 | 168 | 2017 |
Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD HA Baarsma, W Skronska-Wasek, K Mutze, F Ciolek, DE Wagner, ... Journal of Experimental Medicine 214 (1), 143-163, 2017 | 168 | 2017 |
Platelet-derived growth factor signaling in the lung. From lung development and disease to clinical studies N Noskovičová, M Petřek, O Eickelberg, K Heinzelmann American journal of respiratory cell and molecular biology 52 (3), 263-284, 2015 | 101 | 2015 |
FK506-binding protein 10, a potential novel drug target for idiopathic pulmonary fibrosis CA Staab-Weijnitz, IE Fernandez, L Knüppel, J Maul, K Heinzelmann, ... American journal of respiratory and critical care medicine 192 (4), 455-467, 2015 | 97 | 2015 |
Peripheral blood myeloid-derived suppressor cells reflect disease status in idiopathic pulmonary fibrosis IE Fernandez, FR Greiffo, M Frankenberger, J Bandres, K Heinzelmann, ... European Respiratory Journal 48 (4), 1171-1183, 2016 | 66 | 2016 |
Impairment of immunoproteasome function by cigarette smoke and in chronic obstructive pulmonary disease IE Kammerl, A Dann, A Mossina, D Brech, C Lukas, O Vosyka, P Nathan, ... American journal of respiratory and critical care medicine 193 (11), 1230-1241, 2016 | 59 | 2016 |
Cholesterol metabolism promotes B‐cell positioning during immune pathogenesis of chronic obstructive pulmonary disease J Jia, TM Conlon, RSJ Sarker, D Taşdemir, NF Smirnova, B Srivastava, ... EMBO molecular medicine 10 (5), e8349, 2018 | 57 | 2018 |
Glutathione peroxidase 3 localizes to the epithelial lining fluid and the extracellular matrix in interstitial lung disease AC Schamberger, HB Schiller, IE Fernandez, M Sterclova, K Heinzelmann, ... Scientific reports 6 (1), 29952, 2016 | 38 | 2016 |
Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 (vIRF4/K10) is a novel interaction partner of CSL/CBF1, the major downstream effector of Notch … K Heinzelmann, BA Scholz, A Nowak, E Fossum, E Kremmer, J Haas, ... Journal of virology 84 (23), 12255-12264, 2010 | 32 | 2010 |
FK506-binding protein 10 (FKBP10) regulates lung fibroblast migration via collagen VI synthesis L Knüppel, K Heinzelmann, M Lindner, R Hatz, J Behr, O Eickelberg, ... Respiratory Research 19, 1-14, 2018 | 28 | 2018 |
Cell-surface phenotyping identifies CD36 and CD97 as novel markers of fibroblast quiescence in lung fibrosis K Heinzelmann, M Lehmann, M Gerckens, N Noskovičová, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 315 (5 …, 2018 | 25 | 2018 |
Characteristic patterns in the fibrotic lung. Comparing idiopathic pulmonary fibrosis with chronic lung allograft dysfunction IE Fernandez, K Heinzelmann, S Verleden, O Eickelberg Annals of the American Thoracic Society 12 (Supplement 1), S34-S41, 2015 | 19 | 2015 |
Single-cell RNA sequencing identifies G-protein coupled receptor 87 as a basal cell marker expressed in distal honeycomb cysts in idiopathic pulmonary fibrosis K Heinzelmann, Q Hu, Y Hu, E Dobrinskikh, M Ansari, MC Melo-Narváez, ... European Respiratory Journal 2022 Jun; 59(6): 2102373., 2022 | 18 | 2022 |
Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics M Gerckens, K Schorpp, F Pelizza, M Wögrath, K Reichau, H Ma, ... Science Advances 2021 Dec; 7(52): eabb3673., 2021 | 16 | 2021 |
Surface proteome analysis identifies platelet derived growth factor receptor-alpha as a critical mediator of transforming growth factor-beta-induced collagen secretion K Heinzelmann, N Noskovičová, J Merl-Pham, G Preissler, H Winter, ... The international journal of biochemistry & cell biology 74, 44-59, 2016 | 16 | 2016 |
The oncogene ECT2 contributes to a hyperplastic, proliferative lung epithelial cell phenotype in idiopathic pulmonary fibrosis HM Ulke, K Mutze, M Lehmann, DE Wagner, K Heinzelmann, A Günther, ... American Journal of Respiratory Cell and Molecular Biology 61 (6), 713-726, 2019 | 15 | 2019 |
Cub domain-containing protein 1 negatively regulates TGF-β signaling and myofibroblast differentiation N Noskovičová, K Heinzelmann, G Burgstaller, J Behr, O Eickelberg American Journal of Physiology-Lung Cellular and Molecular Physiology 314 (5 …, 2018 | 13 | 2018 |