Internal standards in the quantitative determination of protein biopharmaceuticals using liquid chromatography coupled to mass spectrometry KJ Bronsema, R Bischoff, NC van de Merbel Journal of Chromatography B 893, 1-14, 2012 | 172 | 2012 |
High-sensitivity LC-MS/MS quantification of peptides and proteins in complex biological samples: the impact of enzymatic digestion and internal standard selection on method … KJ Bronsema, R Bischoff, NC van de Merbel Analytical chemistry 85 (20), 9528-9535, 2013 | 104 | 2013 |
A validated liquid chromatography–tandem mass spectrometry method for the quantitative determination of 4β-hydroxycholesterol in human plasma NC van de Merbel, KJ Bronsema, MWJ van Hout, R Nilsson, H Sillén Journal of pharmaceutical and biomedical analysis 55 (5), 1089-1095, 2011 | 57 | 2011 |
Analysis of biopharmaceutical proteins in biological matrices by LC-MS/MS I. Sample preparation R Bischoff, KJ Bronsema, NC van de Merbel TrAC Trends in Analytical Chemistry 48, 41-51, 2013 | 36 | 2013 |
High sustained antibody titers in patients with classic infantile Pompe disease following immunomodulation at start of enzyme replacement therapy E Poelman, M Hoogeveen-Westerveld, MA Kroos-de Haan, ... The Journal of Pediatrics 195, 236-243. e3, 2018 | 31 | 2018 |
Absolute quantification of the total and antidrug antibody-bound concentrations of recombinant human α-glucosidase in human plasma using protein G extraction and LC-MS/MS KJ Bronsema, R Bischoff, WWMP Pijnappel, AT van der Ploeg, ... Analytical chemistry 87 (8), 4394-4401, 2015 | 27 | 2015 |
A quantitative LC-MS/MS method for insulin-like growth factor 1 in human plasma KJ Bronsema, F Klont, FB Schalk, R Bischoff, IP Kema, NC van de Merbel Clinical Chemistry and Laboratory Medicine (CCLM) 56 (11), 1905-1912, 2018 | 23 | 2018 |
High-sensitivity quantitation of a Nanobody® in plasma by singlecartridge multidimensional SPE and ultra-performance LC–MS/MS KJ Bronsema, R Bischoff, MP Bouche, K Mortier, NC van de Merbel Bioanalysis 7 (1), 53-64, 2015 | 15 | 2015 |
Protein quantification using LC–MS: can it make a difference? NC van de Merbel, KJ Bronsema, M Nemansky Bioanalysis 4 (17), 2113-2116, 2012 | 14 | 2012 |
Sensitivity improvement of the LC–MS/MS quantification of carbidopa in human plasma and urine by derivatization with 2, 4-pentanedione NC van de Merbel, KJ Bronsema, SH Gorman, R Bakhtiar Journal of Chromatography B 1064, 62-67, 2017 | 7 | 2017 |
MS quantification of peptides and proteins in complex biological samples: the impact of enzymatic digestion and internal standard selection on method performance KJ Bronsema, R Bischoff, NC van de Merbel, L High-sensitivity Anal Chem 85 (20), 9528-35, 2013 | 5 | 2013 |
Monitoring of the deuterated and nondeuterated forms of levodopa and five metabolites in plasma and urine by LC–MS/MS NC van de Merbel, KJ Bronsema, SH Gorman, R Bakhtiar Bioanalysis 11 (04), 279-293, 2019 | 1 | 2019 |
Development, validation and application of a quantitative LC-MS/MS method for insulin-like growth factor-1 in human plasma. KJ Bronsema, R Bischoff, J Schlaman, FB Schalk, IP Kema, ... Enhancing the possibilities of LC-MS/MS for the absolute quantification of …, 2015 | 1 | 2015 |
Development, validation and application of a liquid chromatography–tandem mass spectrometry method for the activity and inhibition of DPP-4 KJ Bronsema, W Lambert, S Charmont, R Sangana, R Trigt, MA Valentin Bioanalysis 14 (6), 369-378, 2022 | | 2022 |
Antibody formation to enzyme replacement therapy in classic infantile Pompe disease: effects of immunomodulation in naïve patients E Poelman, M Hoogeveen–Westerveld, M Kroos-de Haan, ... Neuromuscular Disorders 27, S162, 2017 | | 2017 |