Symen Ligthart
Symen Ligthart
Erasmus University Medical Center
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DNA methylation in newborns and maternal smoking in pregnancy: genome-wide consortium meta-analysis
BR Joubert, JF Felix, P Yousefi, KM Bakulski, AC Just, C Breton, ...
The American Journal of Human Genetics 98 (4), 680-696, 2016
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
A Mahajan, D Taliun, M Thurner, NR Robertson, JM Torres, NW Rayner, ...
Nature genetics 50 (11), 1505-1513, 2018
Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns
BR Joubert, T Herman, JF Felix, J Bohlin, S Ligthart, E Beckett, H Tiemeier, ...
Nature communications 7 (1), 1-8, 2016
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
A Mahajan, J Wessel, SM Willems, W Zhao, NR Robertson, AY Chu, ...
Nature genetics 50 (4), 559-571, 2018
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases
S Ligthart, C Marzi, S Aslibekyan, MM Mendelson, KN Conneely, ...
Genome biology 17 (1), 1-15, 2016
Lifetime risk of developing impaired glucose metabolism and eventual progression from prediabetes to type 2 diabetes: a prospective cohort study
S Ligthart, TTW van Herpt, MJG Leening, M Kavousi, A Hofman, ...
The lancet Diabetes & endocrinology 4 (1), 44-51, 2016
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis
Interleukin 1 Genetics Consortium
The Lancet Diabetes & Endocrinology 3 (4), 243-253, 2015
Pleiotropic genes for metabolic syndrome and inflammation
AT Kraja, DI Chasman, KE North, AP Reiner, LR Yanek, TO Kilpeläinen, ...
Molecular genetics and metabolism 112 (4), 317-338, 2014
Thyroid function and risk of type 2 diabetes: a population-based prospective cohort study
L Chaker, S Ligthart, TIM Korevaar, A Hofman, OH Franco, RP Peeters, ...
BMC medicine 14 (1), 1-8, 2016
Genome analyses of> 200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders
S Ligthart, A Vaez, U Võsa, MG Stathopoulou, PS De Vries, BP Prins, ...
The American Journal of Human Genetics 103 (5), 691-706, 2018
Vitamin D and C-reactive protein: a Mendelian randomization study
MC Liefaard, S Ligthart, A Vitezova, A Hofman, AG Uitterlinden, ...
PloS one 10 (7), e0131740, 2015
The role of global and regional DNA methylation and histone modifications in glycemic traits and type 2 diabetes: A systematic review
T Muka, J Nano, T Voortman, KVE Braun, S Ligthart, S Stranges, ...
Nutrition, Metabolism and Cardiovascular Diseases 26 (7), 553-566, 2016
Circulating levels of interleukin 1-receptor antagonist and risk of cardiovascular disease: meta-analysis of six population-based cohorts
C Herder, T de Las Heras Gala, M Carstensen-Kirberg, C Huth, A Zierer, ...
Arteriosclerosis, thrombosis, and vascular biology 37 (6), 1222-1227, 2017
DNA methylation analysis identifies loci for blood pressure regulation
MA Richard, T Huan, S Ligthart, R Gondalia, MA Jhun, JA Brody, MR Irvin, ...
The American Journal of Human Genetics 101 (6), 888-902, 2017
Tobacco smoking is associated with methylation of genes related to coronary artery disease
RV Steenaard, S Ligthart, L Stolk, MJ Peters, JB van Meurs, ...
Clinical epigenetics 7 (1), 54, 2015
Age at natural menopause and risk of type 2 diabetes: a prospective cohort study
T Muka, E Asllanaj, N Avazverdi, L Jaspers, N Stringa, J Milic, S Ligthart, ...
Diabetologia 60 (10), 1951-1960, 2017
Serum magnesium and the risk of prediabetes: a population-based cohort study
BCT Kieboom, S Ligthart, A Dehghan, S Kurstjens, JHF de Baaij, ...
Diabetologia 60 (5), 843-853, 2017
EN-RAGE: a novel inflammatory marker for incident coronary heart disease
S Ligthart, S Sedaghat, MA Ikram, A Hofman, OH Franco, A Dehghan
Arteriosclerosis, thrombosis, and vascular biology 34 (12), 2695-2699, 2014
Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation
S Ligthart, A Vaez, YH Hsu, R Stolk, AG Uitterlinden, A Hofman, ...
BMC genomics 17 (1), 443, 2016
Incremental predictive value of 152 single nucleotide polymorphisms in the 10-year risk prediction of incident coronary heart disease: the Rotterdam Study
PS de Vries, M Kavousi, S Ligthart, AG Uitterlinden, A Hofman, OH Franco, ...
International journal of epidemiology 44 (2), 682-688, 2015
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