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Gillian Dekkers
Gillian Dekkers
Scientist, QVQ B.V.
Geverifieerd e-mailadres voor qvquality.com
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IgG subclasses and allotypes: from structure to effector functions
G Vidarsson, G Dekkers, T Rispens
Frontiers in immunology 5, 520, 2014
20002014
Decoding the human immunoglobulin G-glycan repertoire reveals a spectrum of Fc-receptor-and complement-mediated-effector activities
G Dekkers, L Treffers, R Plomp, AEH Bentlage, M de Boer, ...
Frontiers in immunology 8, 877, 2017
2152017
Affinity of human IgG subclasses to mouse Fc gamma receptors
G Dekkers, AEH Bentlage, TC Stegmann, HL Howie, ...
MAbs 9 (5), 767-773, 2017
1152017
Multi-level glyco-engineering techniques to generate IgG with defined Fc-glycans
G Dekkers, R Plomp, CAM Koeleman, R Visser, HH Von Horsten, ...
Scientific reports 6 (1), 1-12, 2016
1102016
Hinge-Region O-Glycosylation of Human Immunoglobulin G3 (IgG3)*[S]
R Plomp, G Dekkers, Y Rombouts, R Visser, CAM Koeleman, ...
Molecular & cellular proteomics 14 (5), 1373-1384, 2015
992015
Inhibition of FcγR-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and FcγRIIb in human macrophages
SQ Nagelkerke, G Dekkers, I Kustiawan, FS van de Bovenkamp, ...
Blood, The Journal of the American Society of Hematology 124 (25), 3709-3718, 2014
882014
Glycosylation pattern of anti‐platelet IgG is stable during pregnancy and predicts clinical outcome in alloimmune thrombocytopenia
ME Sonneveld, S Natunen, S Sainio, CAM Koeleman, S Holst, G Dekkers, ...
British journal of haematology 174 (2), 310-320, 2016
772016
Identification of sequence variants influencing immunoglobulin levels
S Jonsson, G Sveinbjornsson, AL de Lapuente Portilla, B Swaminathan, ...
Nature genetics 49 (8), 1182-1191, 2017
692017
Novel Concepts of altered immunoglobulin G Galactosylation in autoimmune diseases
G Dekkers, T Rispens, G Vidarsson
Frontiers in immunology 9, 553, 2018
622018
Enhanced effector functions due to antibody defucosylation depend on the effector cell Fcγ receptor profile
CW Bruggeman, G Dekkers, AEH Bentlage, LW Treffers, SQ Nagelkerke, ...
The Journal of Immunology 199 (1), 204-211, 2017
592017
Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1
LE McCoy, L Rutten, D Frampton, I Anderson, L Granger, ...
PLoS pathogens 10 (12), e1004552, 2014
472014
Functional attributes of antibodies, effector cells, and target cells affecting NK cell–mediated antibody-dependent cellular cytotoxicity
AR Temming, SW de Taeye, EL de Graaf, LA de Neef, G Dekkers, ...
The Journal of Immunology 203 (12), 3126-3135, 2019
322019
Human DC-SIGN and CD23 do not interact with human IgG
AR Temming, G Dekkers, FS van de Bovenkamp, HR Plomp, ...
Scientific reports 9 (1), 1-10, 2019
322019
Conserved FcγR-glycan discriminates between fucosylated and afucosylated IgG in humans and mice
G Dekkers, AEH Bentlage, R Plomp, R Visser, CAM Koeleman, ...
Molecular immunology 94, 54-60, 2018
232018
Glycoengineering HIV-1 Env creates ‘supercharged’and ‘hybrid’glycans to increase neutralizing antibody potency, breadth and saturation
ET Crooks, SL Grimley, M Cully, K Osawa, G Dekkers, K Saunders, ...
PLoS pathogens 14 (5), e1007024, 2018
202018
Rheumatoid factors do not preferentially bind to ACPA-IgG or IgG with altered galactosylation
WJJ Falkenburg, AC Kempers, G Dekkers, P Ooijevaar-de Heer, ...
Rheumatology 56 (11), 2025-2030, 2017
132017
IgG glyco-engineering to improve IVIg potency
CW Bruggeman, G Dekkers, R Visser, NWM Goes, TK Van den Berg, ...
Frontiers in immunology 9, 2442, 2018
82018
IgG subclass determines suppression versus enhancement of humoral alloimmunity to Kell RBC antigens in mice
P Shinde, HL Howie, TC Stegmann, AM Hay, HR Waterman, Z Szittner, ...
Frontiers in immunology 11, 1516, 2020
52020
Unraveling the Effect of a Potentiating Anti–Factor H Antibody on Atypical Hemolytic Uremic Syndrome–Associated Factor H Variants
G Dekkers, MC Brouwer, J Jeremiasse, A Kamp, RM Biggs, G van Mierlo, ...
The Journal of Immunology 205 (7), 1778-1786, 2020
42020
Biophysical Evaluation of Rhesus Macaque Fc Gamma Receptors Reveals Similar IgG Fc Glycoform Preferences to Human Receptors
AR Crowley, NY Osei-Owusu, G Dekkers, W Gao, M Wuhrer, DM Magnani, ...
Frontiers in immunology, 4279, 2021
32021
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