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Gillian Dekkers
Gillian Dekkers
Scientist, QVQ B.V.
Geverifieerd e-mailadres voor qvquality.com
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IgG subclasses and allotypes: from structure to effector functions
G Vidarsson, G Dekkers, T Rispens
Frontiers in immunology 5, 117227, 2014
29062014
Decoding the human immunoglobulin G-glycan repertoire reveals a spectrum of Fc-receptor-and complement-mediated-effector activities
G Dekkers, L Treffers, R Plomp, AEH Bentlage, M de Boer, ...
Frontiers in immunology 8, 877, 2017
3302017
Affinity of human IgG subclasses to mouse Fc gamma receptors
G Dekkers, AEH Bentlage, TC Stegmann, HL Howie, ...
MAbs 9 (5), 767-773, 2017
2082017
Multi-level glyco-engineering techniques to generate IgG with defined Fc-glycans
G Dekkers, R Plomp, CAM Koeleman, R Visser, HH Von Horsten, ...
Scientific reports 6 (1), 36964, 2016
1432016
Hinge-region O-glycosylation of human immunoglobulin G3 (IgG3)*[S]
R Plomp, G Dekkers, Y Rombouts, R Visser, CAM Koeleman, ...
Molecular & cellular proteomics 14 (5), 1373-1384, 2015
1222015
Glycosylation pattern of anti‐platelet IgG is stable during pregnancy and predicts clinical outcome in alloimmune thrombocytopenia
ME Sonneveld, S Natunen, S Sainio, CAM Koeleman, S Holst, G Dekkers, ...
British journal of haematology 174 (2), 310-320, 2016
1122016
Inhibition of FcγR-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and FcγRIIb in human macrophages
SQ Nagelkerke, G Dekkers, I Kustiawan, FS van de Bovenkamp, ...
Blood, The Journal of the American Society of Hematology 124 (25), 3709-3718, 2014
1112014
Novel Concepts of altered immunoglobulin G Galactosylation in autoimmune diseases
G Dekkers, T Rispens, G Vidarsson
Frontiers in immunology 9, 553, 2018
962018
Identification of sequence variants influencing immunoglobulin levels
S Jonsson, G Sveinbjornsson, AL de Lapuente Portilla, B Swaminathan, ...
Nature genetics 49 (8), 1182-1191, 2017
932017
Enhanced effector functions due to antibody defucosylation depend on the effector cell Fcγ receptor profile
CW Bruggeman, G Dekkers, AEH Bentlage, LW Treffers, SQ Nagelkerke, ...
The Journal of Immunology 199 (1), 204-211, 2017
782017
Functional attributes of antibodies, effector cells, and target cells affecting NK cell–mediated antibody-dependent cellular cytotoxicity
AR Temming, SW de Taeye, EL de Graaf, LA de Neef, G Dekkers, ...
The Journal of Immunology 203 (12), 3126-3135, 2019
752019
Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1
LE McCoy, L Rutten, D Frampton, I Anderson, L Granger, ...
PLoS pathogens 10 (12), e1004552, 2014
532014
Human DC-SIGN and CD23 do not interact with human IgG
AR Temming, G Dekkers, FS van de Bovenkamp, HR Plomp, ...
Scientific reports 9 (1), 9995, 2019
522019
Conserved FcγR-glycan discriminates between fucosylated and afucosylated IgG in humans and mice
G Dekkers, AEH Bentlage, R Plomp, R Visser, CAM Koeleman, ...
Molecular immunology 94, 54-60, 2018
372018
Glycoengineering HIV-1 Env creates ‘supercharged’and ‘hybrid’glycans to increase neutralizing antibody potency, breadth and saturation
ET Crooks, SL Grimley, M Cully, K Osawa, G Dekkers, K Saunders, ...
PLoS pathogens 14 (5), e1007024, 2018
272018
IgG subclass determines suppression versus enhancement of humoral alloimmunity to kell RBC antigens in mice
P Shinde, HL Howie, TC Stegmann, AM Hay, HR Waterman, Z Szittner, ...
Frontiers in immunology 11, 1516, 2020
172020
Rheumatoid factors do not preferentially bind to ACPA-IgG or IgG with altered galactosylation
WJJ Falkenburg, AC Kempers, G Dekkers, P Ooijevaar-de Heer, ...
Rheumatology 56 (11), 2025-2030, 2017
152017
IgG glyco-engineering to improve IVIg potency
CW Bruggeman, G Dekkers, R Visser, NWM Goes, TK Van den Berg, ...
Frontiers in immunology 9, 2442, 2018
112018
Anti-HIV-1 Nanobody-IgG1 constructs with improved neutralization potency and the ability to mediate fc effector functions
AI Schriek, MM van Haaren, M Poniman, G Dekkers, AEH Bentlage, ...
Frontiers in immunology 13, 893648, 2022
102022
Biophysical evaluation of rhesus macaque Fc gamma receptors reveals similar IgG Fc glycoform preferences to human receptors
AR Crowley, NY Osei-Owusu, G Dekkers, W Gao, M Wuhrer, DM Magnani, ...
Frontiers in Immunology 12, 754710, 2021
92021
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