Anatomical and physiological alterations of pregnancy JM Kazma, J van den Anker, K Allegaert, A Dallmann, HK Ahmadzia Journal of Pharmacokinetics and Pharmacodynamics 47 (4), 271–285, 2020 | 143 | 2020 |
Gestation-specific changes in the anatomy and physiology of healthy pregnant women: an extended repository of model parameters for physiologically based pharmacokinetic … A Dallmann, I Ince, M Meyer, S Willmann, T Eissing, G Hempel Clinical pharmacokinetics 56 (11), 1303–1330, 2017 | 102 | 2017 |
Physiologically based pharmacokinetic modeling of renally cleared drugs in pregnant women A Dallmann, I Ince, J Solodenko, M Meyer, S Willmann, T Eissing, ... Clinical pharmacokinetics 56 (12), 1525–1541, 2017 | 77 | 2017 |
A physiologically based pharmacokinetic model for pregnant women to predict the pharmacokinetics of drugs metabolized via several enzymatic pathways A Dallmann, I Ince, K Coboeken, T Eissing, G Hempel Clinical pharmacokinetics 57 (6), 749–768, 2018 | 75 | 2018 |
Physiologically based pharmacokinetic modeling in pregnancy: a systematic review of published models A Dallmann, M Pfister, J van den Anker, T Eissing Clinical Pharmacology & Therapeutics 104 (6), 1110–1124, 2018 | 68 | 2018 |
Drug Transporters Expressed in the Human Placenta and Models for Studying Maternal‐Fetal Drug Transfer A Dallmann, XI Liu, GJ Burckart, J van den Anker The Journal of Clinical Pharmacology 59 (S1), S70–S81, 2019 | 58 | 2019 |
Physiologically Based Pharmacokinetic Modeling to Characterize Acetaminophen Pharmacokinetics and N-Acetyl-p-Benzoquinone Imine (NAPQI) Formation in Non-Pregnant and Pregnant Women P Mian, JN van den Anker, K van Calsteren, P Annaert, D Tibboel, ... Clinical pharmacokinetics 59 (1), 97–110, 2020 | 49 | 2020 |
Applied concepts in PBPK modeling: how to extend an Open Systems Pharmacology model to the special population of pregnant women A Dallmann, J Solodenko, I Ince, T Eissing CPT: pharmacometrics & systems pharmacology 7 (7), 419–431, 2018 | 45 | 2018 |
Physiologically Based Pharmacokinetic Models to Predict Maternal Pharmacokinetics and Fetal Exposure to Emtricitabine and Acyclovir XI Liu, JD Momper, N Rakhmanina, JN van den Anker, DJ Green, ... The Journal of Clinical Pharmacology 60 (2), 240–255, 2020 | 44 | 2020 |
Integration of Placental Transfer in a Fetal–Maternal Physiologically Based Pharmacokinetic Model to Characterize Acetaminophen Exposure and Metabolic Clearance in the Fetus P Mian, K Allegaert, S Conings, P Annaert, D Tibboel, M Pfister, ... Clinical Pharmacokinetics 59 (7), 911–925, 2020 | 42 | 2020 |
Clinical pharmacokinetic studies in pregnant women and the relevance of pharmacometric tools A Dallmann, P Mian, JV den Anker, K Allegaert Current pharmaceutical design 25 (5), 483–495, 2019 | 37 | 2019 |
Predictive Pediatric Modeling and Simulation Using Ontogeny Information I Ince, J Solodenko, S Frechen, A Dallmann, C Niederalt, J Schlender, ... The Journal of Clinical Pharmacology 59 (S1), S95–S103, 2019 | 30 | 2019 |
Monoclonal antibodies and Fc‐fusion proteins for pediatric use: dosing, immunogenicity, and modeling and simulation in data submitted to the US Food and Drug Administration XI Liu, A Dallmann, YM Wang, DJ Green, JM Burnham, B Chiang, P Wu, ... The Journal of Clinical Pharmacology 59 (8), 1130–1143, 2019 | 29 | 2019 |
Best Practices in the Development and Validation of Physiologically Based Biopharmaceutics Modeling. A Workshop Summary Report N Parrott, S Suarez-Sharp, F Kesisoglou, SM Pathak, D Good, C Wagner, ... Journal of Pharmaceutical Sciences 110 (2), 584–593, 2021 | 28 | 2021 |
Prediction of Maternal and Fetal Pharmacokinetics of Dolutegravir and Raltegravir Using Physiologically Based Pharmacokinetic Modeling XI Liu, JD Momper, NY Rakhmanina, DJ Green, GJ Burckart, TR Cressey, ... Clinical Pharmacokinetics 59 (11), 1433–1450, 2020 | 23 | 2020 |
In Vitro Biopredictive Methods: A Workshop Summary Report XJH Pepin, J Dressman, N Parrott, P Delvadia, A Mitra, X Zhang, ... Journal of Pharmaceutical Sciences 110 (2), 567–583, 2021 | 22 | 2021 |
A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug … S Frechen, J Solodenko, T Wendl, A Dallmann, I Ince, T Lehr, J Lippert, ... CPT: pharmacometrics & systems pharmacology 10 (6), 633–644, 2021 | 17 | 2021 |
Integration of physiological changes during the postpartum period into a PBPK framework and prediction of amoxicillin disposition before and shortly after delivery A Dallmann, A Himstedt, J Solodenko, I Ince, G Hempel, T Eissing Journal of Pharmacokinetics and Pharmacodynamics 47 (4), 341–359, 2020 | 16 | 2020 |
Development of a Generic Physiologically Based Pharmacokinetic Model for Lactation and Prediction of Maternal and Infant Exposure to Ondansetron via Breast Milk KM Job, A Dallmann, S Parry, G Saade, DM Haas, B Hughes, P Berens, ... Clinical Pharmacology & Therapeutics 111 (5), 1111–1120, 2022 | 15 | 2022 |
Predictive performance of physiology‐based pharmacokinetic dose estimates for pediatric trials: evaluation with 10 Bayer small‐molecule compounds in children I Ince, A Dallmann, S Frechen, K Coboeken, C Niederalt, T Wendl, ... The Journal of Clinical Pharmacology 61 (Suppl 1), S70–S82, 2021 | 15 | 2021 |