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Fernando J. Rossello
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Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes
E Mariño, JL Richards, KH McLeod, D Stanley, YA Yap, J Knight, ...
Nature immunology 18 (5), 552-562, 2017
6252017
IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
CA Nold-Petry, CY Lo, I Rudloff, KD Elgass, S Li, MP Gantier, ...
Nature immunology 16 (4), 354-365, 2015
4212015
Transcriptional signature in microglia associated with Aβ plaque phagocytosis
A Grubman, XY Choo, G Chew, JF Ouyang, G Sun, NP Croft, FJ Rossello, ...
Nature Communications 12 (1), 1-22, 2021
1582021
Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming
X Liu, CM Nefzger, FJ Rossello, J Chen, AS Knaupp, J Firas, E Ford, ...
Nature methods 14 (11), 1055-1062, 2017
1482017
Reprogramming roadmap reveals route to human induced trophoblast stem cells
X Liu, JF Ouyang, FJ Rossello, JP Tan, KC Davidson, DS Valdes, ...
Nature 586 (7827), 101-107, 2020
1442020
Macrophages provide a transient muscle stem cell niche via NAMPT secretion
D Ratnayake, PD Nguyen, FJ Rossello, VC Wimmer, JL Tan, LA Galvis, ...
Nature 591 (7849), 281-287, 2021
1282021
Transient and permanent reconfiguration of chromatin and transcription factor occupancy drive reprogramming
AS Knaupp, S Buckberry, J Pflueger, SM Lim, E Ford, MR Larcombe, ...
Cell stem cell 21 (6), 834-845. e6, 2017
1132017
Mesenchymal niche-derived neuregulin-1 drives intestinal stem cell proliferation and regeneration of damaged epithelium
T Jardé, WH Chan, FJ Rossello, TK Kahlon, M Theocharous, TK Arackal, ...
Cell stem cell 27 (4), 646-662. e7, 2020
972020
DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia
JMD Legrand, AL Chan, HM La, FJ Rossello, ML Änkö, FV Fuller-Pace, ...
Nature communications 10 (1), 2278, 2019
822019
Identification of dynamic undifferentiated cell states within the male germline
HM La, JA Mäkelä, AL Chan, FJ Rossello, CM Nefzger, JMD Legrand, ...
Nature Communications 9 (1), 2819, 2018
792018
BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs
AJ Sadler, FJ Rossello, L Yu, JA Deane, X Yuan, D Wang, AT Irving, ...
Proceedings of the National Academy of Sciences 112 (5), 1535-1540, 2015
662015
Muscle stem cells undergo extensive clonal drift during tissue growth via Meox1-mediated induction of G2 cell-cycle arrest
PD Nguyen, DB Gurevich, C Sonntag, L Hersey, S Alaei, HT Nim, ...
Cell Stem Cell 21 (1), 107-119. e6, 2017
652017
A synthetic lethal interaction between glutathione synthesis and mitochondrial reactive oxygen species provides a tumor-specific vulnerability dependent on STAT3
DJ Garama, TJ Harris, CL White, FJ Rossello, M Abdul-Hay, DJ Gough, ...
Molecular and cellular biology 35 (21), 3646-3656, 2015
652015
FGFR2 mutation in 46,XY sex reversal with craniosynostosis
S Bagheri-Fam, M Ono, L Li, L Zhao, J Ryan, R Lai, Y Katsura, ...
Human Molecular Genetics 24 (23), 6699-6710, 2015
552015
Cell type of origin dictates the route to pluripotency
CM Nefzger, FJ Rossello, J Chen, X Liu, AS Knaupp, J Firas, JM Paynter, ...
Cell reports 21 (10), 2649-2660, 2017
532017
Low-dose histone deacetylase inhibitor treatment leads to tumor growth arrest and multi-lineage differentiation of malignant rhabdoid tumors
A Muscat, D Popovski, WSN Jayasekara, FJ Rossello, M Ferguson, ...
Clinical Cancer Research 22 (14), 3560-3570, 2016
452016
Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy
KD Marini, DR Croucher, RA McCloy, V Vaghjiani, A Gonzalez-Rajal, ...
Science translational medicine 10 (451), eaat3504, 2018
432018
Genomic characterisation of small cell lung cancer patient-derived xenografts generated from endobronchial ultrasound-guided transbronchial needle aspiration specimens
TL Leong, KD Marini, FJ Rossello, SN Jayasekara, PA Russell, ...
PloS one 9 (9), e106862, 2014
412014
Role of epigenetics in the etiology of germ cell cancer
YG Van Der Zwan, H Stoop, F Rossello, SJ White, LHJ Looijenga
International Journal of Developmental Biology 57 (2-3-4), 299-308, 2013
402013
Seminoma and embryonal carcinoma footprints identified by analysis of integrated genome-wide epigenetic and expression profiles of germ cell cancer cell lines
YG van der Zwan, MA Rijlaarsdam, FJ Rossello, AJ Notini, S de Boer, ...
PloS one 9 (6), e98330, 2014
382014
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