John Robert Coleman
John Robert Coleman
Co-Founder, Senior Advisor at Codagenix
Verified email at
Cited by
Cited by
Adenovirus-associated virus vector–mediated gene transfer in hemophilia B
AC Nathwani, EGD Tuddenham, S Rangarajan, C Rosales, J McIntosh, ...
New England Journal of Medicine 365 (25), 2357-2365, 2011
Virus attenuation by genome-scale changes in codon pair bias
JR Coleman, D Papamichail, S Skiena, B Futcher, E Wimmer, S Mueller
Science 320 (5884), 1784-1787, 2008
Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivity
S Mueller, D Papamichail, JR Coleman, S Skiena, E Wimmer
Journal of virology 80 (19), 9687-9696, 2006
Long-term safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins
AC Nathwani, C Rosales, J McIntosh, G Rastegarlari, D Nathwani, D Raj, ...
Molecular therapy 19 (5), 876-885, 2011
Live attenuated influenza virus vaccines by computer-aided rational design
S Mueller, JR Coleman, D Papamichail, CB Ward, A Nimnual, B Futcher, ...
Nature biotechnology 28 (7), 723-726, 2010
The PB1-F2 protein of Influenza A virus: increasing pathogenicity by disrupting alveolar macrophages
JR Coleman
Virology journal 4 (1), 1-5, 2007
Putting synthesis into biology: a viral view of genetic engineering through de novo gene and genome synthesis
S Mueller, JR Coleman, E Wimmer
Chemistry & biology 16 (3), 337-347, 2009
Designed Reduction of Streptococcus pneumoniae Pathogenicity via Synthetic Changes in Virulence Factor Codon-pair Bias
JR Coleman, D Papamichail, M Yano, MM García-Suárez, L Pirofski
Journal of Infectious Diseases 203 (9), 1264-1273, 2011
Scalable live-attenuated SARS-CoV-2 vaccine candidate demonstrates preclinical safety and efficacy
Y Wang, C Yang, Y Song, JR Coleman, M Stawowczyk, J Tafrova, ...
Proceedings of the National Academy of Sciences 118 (29), e2102775118, 2021
Antibodies to Streptococcus pneumoniae capsular polysaccharide enhance pneumococcal quorum sensing
M Yano, S Gohil, JR Coleman, C Manix, L Pirofski
MBio 2 (5), e00176-11, 2011
Medication administration: the implementation process of bar-coding for medication administration to enhance medication safety
SO Foote, JR Coleman
Nursing Economics 26 (3), 207-211, 2008
A codon-pair deoptimized live-attenuated vaccine against respiratory syncytial virus is immunogenic and efficacious in non-human primates
S Mueller, CB Stauft, R Kalkeri, F Koidei, A Kushnir, S Tasker, ...
Vaccine 38 (14), 2943-2948, 2020
Early clinical trial results following administration of a low dose of a novel self complementary adeno-associated viral vector encoding human Factor IX in two subjects with …
A Nathwani, E Tuddenham, C Rosales, J McIntosh, A Riddell, P Rustagi, ...
Blood 116 (21), 248, 2010
Live-attenuated H1N1 influenza vaccine candidate displays potent efficacy in mice and ferrets
CB Stauft, C Yang, JR Coleman, D Boltz, C Chin, A Kushnir, S Mueller
PloS one 14 (10), e0223784, 2019
Vaccination of pigs with a codon-pair bias de-optimized live attenuated influenza vaccine protects from homologous challenge
BS Kaplan, CK Souza, PC Gauger, CB Stauft, JR Coleman, S Mueller, ...
Vaccine 36 (8), 1101-1107, 2018
Codon context optimization in synthetic gene design
D Papamichail, H Liu, V Machado, N Gould, JR Coleman, G Papamichail
IEEE/ACM Transactions on Computational Biology and Bioinformatics 15 (2 …, 2016
An Ahemolytic Pneumolysin of Streptococcus Pneumoniae Manipulates Human Innate and CD4+ T-Cell Responses and Reduces Resistance to Colonization in …
MN Khan, JR Coleman, J Vernatter, AK Varshney, C Dufaud, L Pirofski
The Journal of infectious diseases 210 (10), 1658-1669, 2014
Attenuated viruses useful for vaccines
E Wimmer, S Skiena, S Mueller, B Futcher, D Papamichail, JR Coleman, ...
US Patent 9,476,032, 2016
Attenuated influenza viruses and vaccines
E Wimmer, S Skiena, S Mueller, B Futcher, D Papamichail, JR Coleman, ...
US Patent App. 13/501,045, 2012
Tailoring the immune response via customization of pathogen gene expression
LM Runco, CB Stauft, JR Coleman
Journal of Pathogens 2014, 2014
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