Regulation of progenitor cell proliferation and granulocyte function by microRNA-223 JB Johnnidis, MH Harris, RT Wheeler, S Stehling-Sun, MH Lam, O Kirak, ... Nature 451 (7182), 1125-1129, 2008 | 1426 | 2008 |
Yap1 acts downstream of α-catenin to control epidermal proliferation K Schlegelmilch, M Mohseni, O Kirak, J Pruszak, JR Rodriguez, D Zhou, ... Cell 144 (5), 782-795, 2011 | 1095 | 2011 |
Microfluidic control of cell pairing and fusion AM Skelley, O Kirak, H Suh, R Jaenisch, J Voldman Nature methods 6 (2), 147-152, 2009 | 690 | 2009 |
Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival A Efeyan, R Zoncu, S Chang, I Gumper, H Snitkin, RL Wolfson, O Kirak, ... Nature 493 (7434), 679-683, 2013 | 498 | 2013 |
Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer K Kim, K Ng, PJ Rugg-Gunn, JH Shieh, O Kirak, R Jaenisch, T Wakayama, ... Cell stem cell 1 (3), 346-352, 2007 | 186 | 2007 |
Mir-290–295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects LA Medeiros, LM Dennis, ME Gill, H Houbaviy, S Markoulaki, D Fu, ... Proceedings of the National Academy of Sciences 108 (34), 14163-14168, 2011 | 175 | 2011 |
A latent pro-survival function for the mir-290-295 cluster in mouse embryonic stem cells GXY Zheng, A Ravi, JM Calabrese, LA Medeiros, O Kirak, LM Dennis, ... PLoS genetics 7 (5), e1002054, 2011 | 115 | 2011 |
Enzymatic blockade of the ubiquitin-proteasome pathway R Ernst, JHL Claessen, B Mueller, S Sanyal, E Spooner, AG van der Veen, ... PLoS biology 8 (3), e1000605, 2011 | 103 | 2011 |
Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors J Kim, CJ Lengner, O Kirak, J Hanna, JP Cassady, MA Lodato, S Wu, ... Stem cells 29 (6), 992-1000, 2011 | 98 | 2011 |
RagA, but not RagB, is essential for embryonic development and adult mice A Efeyan, LD Schweitzer, AM Bilate, S Chang, O Kirak, DW Lamming, ... Developmental cell 29 (3), 321-329, 2014 | 93 | 2014 |
Insulin-like growth factor-binding protein 2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells HD Huynh, S Iizuka, M Kaba, O Kirak, J Zheng, HF Lodish, CC Zhang Stem cells 26 (6), 1628-1635, 2008 | 79 | 2008 |
Particle capture devices and methods of use thereof J Voldman, AM Skelley, O Kirak, R Jaenisch US Patent 9,201,060, 2015 | 77 | 2015 |
Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT O Kirak, EM Frickel, GM Grotenbreg, H Suh, R Jaenisch, HL Ploegh Science 328 (5975), 243-248, 2010 | 67 | 2010 |
TRF2-mediated telomere protection is dispensable in pluripotent stem cells M Markiewicz-Potoczny, A Lobanova, AM Loeb, O Kirak, T Olbrich, S Ruiz, ... Nature 589 (7840), 110-115, 2021 | 58 | 2021 |
Cell-specific TLR9 trafficking in primary APCs of transgenic TLR9-GFP mice AM Avalos, O Kirak, JM Oelkers, MC Pils, YM Kim, M Ottinger, R Jaenisch, ... The Journal of Immunology 190 (2), 695-702, 2013 | 42 | 2013 |
Ubiquitin-dependent control of class II MHC localization is dispensable for antigen presentation and antibody production AM McGehee, K Strijbis, E Guillen, T Eng, O Kirak, HL Ploegh PloS one 6 (4), e18817, 2011 | 26 | 2011 |
A catalytically inactive mutant of the deubiquitylase YOD-1 enhances antigen cross-presentation S Sehrawat, PA Koenig, O Kirak, C Schlieker, M Fankhauser, HL Ploegh Blood, The Journal of the American Society of Hematology 121 (7), 1145-1156, 2013 | 22 | 2013 |
CD8+ T cells from mice transnuclear for a TCR that recognizes a single H-2Kb-restricted MHV68 epitope derived from gB-ORF8 help control infection S Sehrawat, O Kirak, PA Koenig, MK Isaacson, S Marques, G Bozkurt, ... Cell Reports 1 (5), 461-471, 2012 | 20 | 2012 |
IGFBP2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells H Huynh, S LIizuka, M Kaba, O Kirak, J Zheng, HF Lodish, CC Zhang Stem Cells 26 (6), 1628-1635, 2008 | 12 | 2008 |
A novel, nonanaphylactogenic, bispecific IgE-CD3 antibody eliminates IgE+ B cells O Kirak, G Riethmüller Journal of Allergy and Clinical Immunology 136 (3), 800-802. e3, 2015 | 8 | 2015 |