| Hypothalamic tanycytes are an ERK-gated conduit for leptin into the brain E Balland, J Dam, F Langlet, E Caron, S Steculorum, A Messina, S Rasika, ... Cell metabolism 19 (2), 293-301, 2014 | 451 | 2014 |
| Sedimentation equilibrium analysis of protein interactions with global implicit mass conservation constraints and systematic noise decomposition J Vistica, J Dam, A Balbo, E Yikilmaz, RA Mariuzza, TA Rouault, P Schuck Analytical biochemistry 326 (2), 234-256, 2004 | 391 | 2004 |
| The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization A Levoye, J Dam, MA Ayoub, JL Guillaume, C Couturier, P Delagrange, ... The EMBO journal 25 (13), 3012-3023, 2006 | 387 | 2006 |
| Calculating sedimentation coefficient distributions by direct modeling of sedimentation velocity concentration profiles J Dam, P Schuck Methods in enzymology 384, 185-212, 2004 | 326 | 2004 |
| Sedimentation velocity analysis of heterogeneous protein-protein interactions: Lamm equation modeling and sedimentation coefficient distributions c (s) J Dam, CA Velikovsky, RA Mariuzza, C Urbanke, P Schuck Biophysical journal 89 (1), 619-634, 2005 | 209 | 2005 |
| Do orphan G‐protein‐coupled receptors have ligand‐independent functions? New insights from receptor heterodimers A Levoye, J Dam, MA Ayoub, JL Guillaume, R Jockers EMBO reports 7 (11), 1094-1098, 2006 | 184 | 2006 |
| Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2Kb J Dam, R Guan, K Natarajan, N Dimasi, LK Chlewicki, DM Kranz, ... Nature immunology 4 (12), 1213-1222, 2003 | 164 | 2003 |
| Sedimentation velocity analysis of heterogeneous protein-protein interactions: sedimentation coefficient distributions c (s) and asymptotic boundary profiles from Gilbert … J Dam, P Schuck Biophysical journal 89 (1), 651-666, 2005 | 125 | 2005 |
| Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity C Couturier, C Sarkis, K Séron, S Belouzard, P Chen, A Lenain, L Corset, ... Proceedings of the National Academy of Sciences 104 (49), 19476-19481, 2007 | 117 | 2007 |
| A role for the melatonin-related receptor GPR50 in leptin signaling, adaptive thermogenesis, and torpor DA Bechtold, A Sidibe, BRC Saer, J Li, LE Hand, EA Ivanova, VM Darras, ... Current biology 22 (1), 70-77, 2012 | 104 | 2012 |
| New pharmacological perspectives for the leptin receptor in the treatment of obesity C Roujeau, R Jockers, J Dam Frontiers in endocrinology 5, 112243, 2014 | 80 | 2014 |
| Nocturnal activation of melatonin receptor type 1 signaling modulates diurnal insulin sensitivity via regulation of PI 3K activity S Owino, A Sánchez‐Bretaño, C Tchio, E Cecon, A Karamitri, J Dam, ... Journal of pineal research 64 (3), e12462, 2018 | 78 | 2018 |
| Leptin brain entry via a tanycytic LepR–EGFR shuttle controls lipid metabolism and pancreas function M Duquenne, C Folgueira, C Bourouh, M Millet, A Silva, J Clasadonte, ... Nature metabolism 3 (8), 1071-1090, 2021 | 74 | 2021 |
| Techniques: new pharmacological perspectives for the leptin receptor F Peelman, C Couturier, J Dam, L Zabeau, J Tavernier, R Jockers Trends in pharmacological sciences 27 (4), 218-225, 2006 | 67 | 2006 |
| Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors L Deng, S Cho, EL Malchiodi, MC Kerzic, J Dam, RA Mariuzza Journal of biological chemistry 283 (24), 16840-16849, 2008 | 63 | 2008 |
| Homozygous deletion of an 80 kb region comprising part of DNAJC6 and LEPR genes on chromosome 1P31. 3 is associated with early onset obesity, mental retardation and epilepsy V Vauthier, S Jaillard, H Journel, C Dubourg, R Jockers, J Dam Molecular genetics and metabolism 106 (3), 345-350, 2012 | 58 | 2012 |
| Endospanins regulate a postinternalization step of the leptin receptor endocytic pathway K Séron, C Couturier, S Belouzard, J Bacart, D Monté, L Corset, ... Journal of Biological Chemistry 286 (20), 17968-17981, 2011 | 56 | 2011 |
| Increased expression of fibroblast growth factor 21 (FGF21) during chronic undernutrition causes growth hormone insensitivity in chondrocytes by inducing leptin receptor … S Wu, T Grunwald, A Kharitonenkov, J Dam, R Jockers, F De Luca Journal of Biological Chemistry 288 (38), 27375-27383, 2013 | 53 | 2013 |
| Variable dimerization of the Ly49A natural killer cell receptor results in differential engagement of its MHC class I ligand J Dam, J Baber, A Grishaev, EL Malchiodi, P Schuck, A Bax, RA Mariuzza Journal of molecular biology 362 (1), 102-113, 2006 | 38 | 2006 |
| The orphan GPR50 receptor promotes constitutive TGFβ receptor signaling and protects against cancer development S Wojciech, R Ahmad, Z Belaid-Choucair, AS Journé, S Gallet, J Dam, ... Nature Communications 9 (1), 1216, 2018 | 36 | 2018 |
