A. S. Lewin
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Geciteerd door
Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa
AS Lewin, KA Drenser, WW Hauswirth, S Nishikawa, D Yasumura, ...
Nature medicine 4 (8), 967-971, 1998
High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors
H Petrs-Silva, A Dinculescu, Q Li, SH Min, V Chiodo, JJ Pang, L Zhong, ...
Molecular therapy 17 (3), 463-471, 2009
Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD
SK Mitter, C Song, X Qi, H Mao, H Rao, D Akin, A Lewin, M Grant, ...
Autophagy 10 (11), 1989-2005, 2014
A comprehensive review of retinal gene therapy
SE Boye, SL Boye, AS Lewin, WW Hauswirth
Molecular therapy 21 (3), 509-519, 2013
Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice
E Rodriguez-Lebron, EM Denovan-Wright, K Nash, AS Lewin, RJ Mandel
Molecular therapy 12 (4), 618-633, 2005
Gene therapy rescues photoreceptor blindness in dogs and paves the way for treating human X-linked retinitis pigmentosa
WA Beltran, AV Cideciyan, AS Lewin, S Iwabe, H Khanna, A Sumaroka, ...
Proceedings of the National Academy of Sciences 109 (6), 2132-2137, 2012
Rescue of a mitochondrial deficiency causing Leber hereditary optic neuropathy
J Guy, X Qi, F Pallotti, EA Schon, G Manfredi, V Carelli, A Martinuzzi, ...
Annals of Neurology: Official Journal of the American Neurological …, 2002
Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina
H Petrs-Silva, A Dinculescu, Q Li, WT Deng, J Pang, SH Min, V Chiodo, ...
Molecular Therapy 19 (2), 293-301, 2011
Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78
MS Gorbatyuk, T Knox, MM LaVail, OS Gorbatyuk, SM Noorwez, ...
Proceedings of the National Academy of Sciences 107 (13), 5961-5966, 2010
Ribozyme rescue of photoreceptor cells in P23H transgenic rats: long-term survival and late-stage therapy
MM LaVail, D Yasumura, MT Matthes, KA Drenser, JG Flannery, AS Lewin, ...
Proceedings of the National Academy of Sciences 97 (21), 11488-11493, 2000
SOD2 knockdown mouse model of early AMD
V Justilien, JJ Pang, K Renganathan, X Zhan, JW Crabb, SR Kim, ...
Investigative ophthalmology & visual science 48 (10), 4407-4420, 2007
In vivo RNAi-mediated α-synuclein silencing induces nigrostriatal degeneration
OS Gorbatyuk, S Li, K Nash, M Gorbatyuk, AS Lewin, LF Sullivan, ...
Molecular Therapy 18 (8), 1450-1457, 2010
[48] Production and purification of recombinant adeno-associated virus
WW Hauswirth, AS Lewin, S Zolotukhin, N Muzyczka
Methods in enzymology 316, 743-761, 2000
Ribozyme gene therapy: applications for molecular medicine
AS Lewin, WW Hauswirth
Trends in molecular medicine 7 (5), 221-228, 2001
ACE2 and Ang-(1-7) confer protection against development of diabetic retinopathy
A Verma, Z Shan, B Lei, L Yuan, X Liu, T Nakagawa, MB Grant, AS Lewin, ...
Molecular therapy 20 (1), 28-36, 2012
Glucose regulated protein 78 diminishes α-synuclein neurotoxicity in a rat model of Parkinson disease
MS Gorbatyuk, A Shabashvili, W Chen, C Meyers, LF Sullivan, M Salganik, ...
Molecular Therapy 20 (7), 1327-1337, 2012
Gene delivery to mitochondria by targeting modified adenoassociated virus suppresses Leber’s hereditary optic neuropathy in a mouse model
H Yu, RD Koilkonda, TH Chou, V Porciatti, SS Ozdemir, V Chiodo, ...
Proceedings of the National Academy of Sciences 109 (20), E1238-E1247, 2012
Mitochondrial protein nitration primes neurodegeneration in experimental autoimmune encephalomyelitis
X Qi, AS Lewin, L Sun, WW Hauswirth, J Guy
Journal of Biological Chemistry 281 (42), 31950-31962, 2006
Citrate synthase encoded by the CIT2 gene of Saccharomyces cerevisiae is peroxisomal
AS Lewin, V Hines, GM Small
Molecular and Cellular Biology 10 (4), 1399-1405, 1990
Suppression of mitochondrial oxidative stress provides long-term neuroprotection in experimental optic neuritis
X Qi, AS Lewin, L Sun, WW Hauswirth, J Guy
Investigative ophthalmology & visual science 48 (2), 681-691, 2007
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