Fredj Ben Bdira
Fredj Ben Bdira
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Stabilization of glucocerebrosidase by active site occupancy
F Ben Bdira, WW Kallemeijn, SV Oussoren, S Scheij, B Bleijlevens, ...
ACS chemical biology 12 (7), 1830-1841, 2017
Tuning intracellular homeostasis of human uroporphyrinogen III synthase by enzyme engineering at a single hotspot of congenital erythropoietic porphyria
F ben Bdira, E González, P Pluta, A Laín, A Sanz-Parra, JM Falcon-Perez, ...
Human molecular genetics 23 (21), 5805-5813, 2014
Repurposing ciclopirox as a pharmacological chaperone in a model of congenital erythropoietic porphyria
P Urquiza, A Laín, A Sanz-Parra, J Moreno, G Bernardo-Seisdedos, ...
Science translational medicine 10 (459), eaat7467, 2018
Hydrophobic interactions contribute to conformational stabilization of endoglycoceramidase II by mechanism-based probes
F Ben Bdira, J Jiang, W Kallemeijn, A de Haan, BI Florea, B Bleijlevens, ...
Biochemistry 55 (34), 4823-4835, 2016
Distinguishing the differences in β-glycosylceramidase folds, dynamics, and actions informs therapeutic uses
FB Bdira, M Artola, HS Overkleeft, M Ubbink, JMFG Aerts
Journal of lipid research 59 (12), 2262-2276, 2018
Structural basis for osmotic regulation of the DNA binding properties of H-NS proteins
L Qin, FB Bdira, YGJ Sterckx, AN Volkov, J Vreede, G Giachin, ...
Nucleic Acids Research 48 (4), 2156-2172, 2020
Catalysis by a rigid enzyme
FB Bdira, CA Waudby, AN Volkov, SP Schröder, E AB, JDC Codée, ...
bioRxiv, 815415, 2019
Understanding functional dynamics and conformational stability of beta-glycosidases
F Ben Bdira
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