Alessandro Aiuti
Alessandro Aiuti
TIGET; Istituto Scientifico San Raffaele; Università Vita Salute San Raffaele
Geverifieerd e-mailadres voor hsr.it
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A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)
CC Bleul, RC Fuhlbrigge, JM Casasnovas, A Aiuti, TA Springer
The Journal of experimental medicine 184 (3), 1101-1109, 1996
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ...
Science 370 (6515), eabd4585, 2020
The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to …
A Aiuti, IJ Webb, C Bleul, T Springer, JC Gutierrez-Ramos
The Journal of experimental medicine 185 (1), 111-120, 1997
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning
A Aiuti, S Slavin, M Aker, F Ficara, S Deola, A Mortellaro, S Morecki, ...
Science 296 (5577), 2410-2413, 2002
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy
A Biffi, E Montini, L Lorioli, M Cesani, F Fumagalli, T Plati, C Baldoli, ...
Science 341 (6148), 1233158, 2013
Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome
A Aiuti, L Biasco, S Scaramuzza, F Ferrua, MP Cicalese, C Baricordi, ...
Science 341 (6148), 1233151, 2013
Gene therapy for immunodeficiency due to adenosine deaminase deficiency
A Aiuti, F Cattaneo, S Galimberti, U Benninghoff, B Cassani, L Callegaro, ...
New England Journal of Medicine 360 (5), 447-458, 2009
Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial
M Sessa, L Lorioli, F Fumagalli, S Acquati, D Redaelli, C Baldoli, ...
The Lancet 388 (10043), 476-487, 2016
Hot spots of retroviral integration in human CD34+ hematopoietic cells
C Cattoglio, G Facchini, D Sartori, A Antonelli, A Miccio, B Cassani, ...
Blood, The Journal of the American Society of Hematology 110 (6), 1770-1778, 2007
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy
A Aiuti, B Cassani, G Andolfi, M Mirolo, L Biasco, A Recchia, F Urbinati, ...
The Journal of clinical investigation 117 (8), 2233-2240, 2007
Recent advances in understanding the pathophysiology of Wiskott-Aldrich syndrome
M Bosticardo, F Marangoni, A Aiuti, A Villa, M Grazia Roncarolo
Blood, The Journal of the American Society of Hematology 113 (25), 6288-6295, 2009
Expression of CXCR4, the receptor for stromal cell‐derived factor‐1 on fetal and adult human lymphohematopoietic progenitors
A Aiuti, M Tavian, A Cipponi, F Ficara, E Zappone, J Hoxie, B Peault, ...
European journal of immunology 29 (6), 1823-1831, 1999
Coronavirus disease 2019 in patients with inborn errors of immunity: an international study
I Meyts, G Bucciol, I Quinti, B Neven, A Fischer, E Seoane, ...
Journal of Allergy and Clinical Immunology 147 (2), 520-531, 2021
A map of human circular RNAs in clinically relevant tissues
PG Maass, P Glažar, S Memczak, G Dittmar, I Hollfinger, L Schreyer, ...
Journal of molecular medicine 95 (11), 1179-1189, 2017
Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement
A Aiuti, S Vai, A Mortellaro, G Casorati, F Ficara, G Andolfi, G Ferrari, ...
Nature medicine 8 (5), 423-425, 2002
How I treat ADA deficiency
HB Gaspar, A Aiuti, F Porta, F Candotti, MS Hershfield, LD Notarangelo
Blood, The Journal of the American Society of Hematology 114 (17), 3524-3532, 2009
Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation
L Dupré, A Aiuti, S Trifari, S Martino, P Saracco, C Bordignon, ...
Immunity 17 (2), 157-166, 2002
Gene therapy for ADA‐SCID, the first marketing approval of an ex vivo gene therapy in Europe: paving the road for the next generation of advanced therapy …
A Aiuti, MG Roncarolo, L Naldini
EMBO molecular medicine 9 (6), 737-740, 2017
Primary immunodeficiency diseases: genomic approaches delineate heterogeneous Mendelian disorders
A Stray-Pedersen, HS Sorte, P Samarakoon, T Gambin, IK Chinn, ...
Journal of Allergy and Clinical Immunology 139 (1), 232-245, 2017
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths
P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ...
Science immunology 6 (62), eabl4340, 2021
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