Thomas Lloyd Williams
Thomas Lloyd Williams
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Membrane and surface interactions of Alzheimer’s Aβ peptide–insights into the mechanism of cytotoxicity
TL Williams, LC Serpell
The FEBS journal 278 (20), 3905-3917, 2011
Surface design: applications in bioscience and nanotechnology
R Förch, H Schönherr, ATA Jenkins
John Wiley & Sons, 2009
Structural basis for increased toxicity of pathological aβ42: aβ40 ratios in Alzheimer disease
K Pauwels, TL Williams, KL Morris, W Jonckheere, A Vandersteen, ...
Journal of biological chemistry 287 (8), 5650-5660, 2012
A central role for dityrosine crosslinking of Amyloid-β in Alzheimer’s disease
YK Al-Hilaly, TL Williams, M Stewart-Parker, L Ford, E Skaria, M Cole, ...
Acta neuropathologica communications 1, 1-17, 2013
Aβ42 oligomers, but not fibrils, simultaneously bind to and cause damage to ganglioside-containing lipid membranes
TL Williams, BRG Johnson, B Urbanc, ATA Jenkins, SDA Connell, ...
Biochemical Journal 439 (1), 67-77, 2011
The effect of Alzheimer’s Aβ aggregation state on the permeation of biomimetic lipid vesicles
TL Williams, IJ Day, LC Serpell
Langmuir 26 (22), 17260-17268, 2010
Characterizing the assembly of the Sup35 yeast prion fragment, GNNQQNY: structural changes accompany a fiber-to-crystal switch
KE Marshall, MR Hicks, TL Williams, SV Hoffmann, A Rodger, TR Dafforn, ...
Biophysical journal 98 (2), 330-338, 2010
Visualization of co-localization in Aβ42-administered neuroblastoma cells reveals lysosome damage and autophagosome accumulation related to cell death
V Soura, M Stewart-Parker, TL Williams, A Ratnayaka, J Atherton, ...
Biochemical Journal 441 (2), 579-590, 2012
Stabilization of native amyloid β-protein oligomers by Copper and Hydrogen peroxide Induced Cross-linking of Unmodified Proteins (CHICUP)
TL Williams, LC Serpell, B Urbanc
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1864 (3), 249-259, 2016
Heme stabilization of α-Synuclein oligomers during amyloid fibril formation.
DLR Eric Yale Hayden , Prerna Kaur , Thomas Lloyd Williams , Hiroshi Matsui ...
Biochemistry, 2015
Effects of Aβ exposure on long-term associative memory and its neuronal mechanisms in a defined neuronal network
L Ford, M Crossley, T Williams, J Thorpe, L Serpell, G Kemenes
Measurement of the binding of cholera toxin to GM1 gangliosides on solid supported lipid bilayer vesicles and inhibition by europium (III) chloride
TL Williams, ATA Jenkins
Journal of the American Chemical Society 130 (20), 6438-6443, 2008
Optical waveguide spectroscopy study of the transport and binding of cytochrome c in mesoporous titanium dioxide electrodes.
PJ Cameron, ATA Jenkins, W Knoll, F Marken, EV Milsom, TL Williams
Journal of Materials Chemistry 18 (36), 4304-4310, 2008
Attachment and phospholipase A2-induced lysis of phospholipid bilayer vesicles to plasma-polymerized maleic anhydride/SiO2 multilayers
AN Chifen, R Förch, W Knoll, PJ Cameron, HL Khor, TL Williams, ...
Langmuir 23 (11), 6294-6298, 2007
Elucidation of insulin assembly at acidic and neutral pH: Characterization of low molecular weight oligomers
MT Mawhinney, TL Williams, JL Hart, ML Taheri, B Urbanc
Proteins: Structure, Function, and Bioinformatics 85 (11), 2096-2110, 2017
Soluble prion protein binds isolated low molecular weight amyloid-β oligomers causing cytotoxicity inhibition
TL Williams, JK Choi, K Surewicz, WK Surewicz
ACS chemical neuroscience 6 (12), 1972-1980, 2015
Fluorophore-encapsulated solid-supported bilayer vesicles: A method for studying membrane permeation processes
TL Williams, MMLM Vareiro, ATA Jenkins
Langmuir 22 (15), 6473-6476, 2006
Insulin inhibits Aβ42 aggregation and prevents Aβ42-induced membrane disruption
K Long, TL Williams, B Urbanc
Biochemistry 58 (45), 4519-4529, 2019
Europium as an inhibitor of Amyloid-β (1-42) induced membrane permeation
TL Williams, B Urbanc, KE Marshall, DM Vadukul, ATA Jenkins, ...
FEBS letters 589 (21), 3228-3236, 2015
Monitoring Changes of Paramagnetically-Shifted 31 P Signals in Phospholipid Vesicles
IJ Joyce, Rebecca E, Williams, Thomas L, Serpell, Louise C and Day
Chemical Physics Letters 648, 124-129, 2016
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