| Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease EF Remmers, F Cosan, Y Kirino, MJ Ombrello, N Abaci, C Satorius, JM Le, ... Nature genetics 42 (8), 698-702, 2010 | 759 | 2010 |
| Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1 Y Kirino, G Bertsias, Y Ishigatsubo, N Mizuki, I Tugal-Tutkun, E Seyahi, ... Nature genetics 45 (2), 202-207, 2013 | 587 | 2013 |
| Targeted resequencing implicates the familial Mediterranean fever gene MEFV and the toll-like receptor 4 gene TLR4 in Behçet disease Y Kirino, Q Zhou, Y Ishigatsubo, N Mizuki, I Tugal-Tutkun, E Seyahi, ... Proceedings of the National Academy of Sciences 110 (20), 8134-8139, 2013 | 176 | 2013 |
| Behcet disease-associated MHC class I residues implicate antigen binding and regulation of cell-mediated cytotoxicity MJ Ombrello, Y Kirino, PIW de Bakker, A Gül, DL Kastner, EF Remmers Proceedings of the National Academy of Sciences 111 (24), 8867-8872, 2014 | 164 | 2014 |
| Dense genotyping of immune-related loci implicates host responses to microbial exposure in Behcet's disease susceptibility M Takeuchi, N Mizuki, A Meguro, MJ Ombrello, Y Kirino, C Satorius, J Le, ... Nature genetics 49 (3), 438-443, 2017 | 150 | 2017 |
| Regulatory role of heme oxygenase 1 in inflammation of rheumatoid arthritis H Kobayashi, M Takeno, T Saito, Y Takeda, Y Kirino, K Noyori, T Hayashi, ... Arthritis & Rheumatism 54 (4), 1132-1142, 2006 | 140 | 2006 |
| Brief Report: Takayasu Arteritis and Ulcerative Colitis: High Rate of Co‐Occurrence and Genetic Overlap C Terao, T Matsumura, H Yoshifuji, Y Kirino, Y Maejima, Y Nakaoka, ... Arthritis & rheumatology 67 (8), 2226-2232, 2015 | 123 | 2015 |
| Pathogenic UBA1 variants associated with VEXAS syndrome in Japanese patients with relapsing polychondritis N Tsuchida, Y Kunishita, Y Uchiyama, Y Kirino, M Enaka, Y Yamaguchi, ... Annals of the rheumatic diseases 80 (8), 1057-1061, 2021 | 100 | 2021 |
| Expression of heme oxygenase‐1 in human leukemic cells and its regulation by transcriptional repressor Bach1 T Miyazaki, Y Kirino, M Takeno, S Samukawa, M Hama, M Tanaka, ... Cancer science 101 (6), 1409-1416, 2010 | 95 | 2010 |
| Increased serum HO-1 in hemophagocytic syndrome and adult-onset Still's disease: use in the differential diagnosis of hyperferritinemia Y Kirino, M Takeno, M Iwasaki, A Ueda, S Ohno, A Shirai, H Kanamori, ... Arthritis research & therapy 7, 1-9, 2005 | 94 | 2005 |
| Diagnostic test accuracy of ultrasound for synovitis in rheumatoid arthritis: systematic review and meta-analysis K Takase-Minegishi, N Horita, K Kobayashi, R Yoshimi, Y Kirino, S Ohno, ... Rheumatology 57 (1), 49-58, 2018 | 85 | 2018 |
| Neurological manifestations of Behçet’s disease in Japan: a study of 54 patients H Ideguchi, A Suda, M Takeno, Y Kirino, A Ihata, A Ueda, S Ohno, Y Baba, ... Journal of neurology 257, 1012-1020, 2010 | 85 | 2010 |
| Simultaneous evaluation of long-lasting knee synovitis in patients undergoing arthroplasty by power Doppler ultrasonography and contrast-enhanced MRI in comparison with … K Takase, S Ohno, M Takeno, M Hama, Y Kirino, A Ihata, H Ideguchi, ... Clinical and Experimental Rheumatology-Incl Supplements 30 (1), 85, 2012 | 82 | 2012 |
| Chemical induction of HO-1 suppresses lupus nephritis by reducing local iNOS expression and synthesis of anti-dsDNA antibody Y Takeda, M Takeno, M Iwasaki, H KObayashi, Y Kirino, A Ueda, ... Clinical & Experimental Immunology 138 (2), 237-244, 2004 | 82 | 2004 |
| Clinical manifestations of Behçet’s disease depending on sex and age: results from Japanese nationwide registration T Ishido, N Horita, M Takeuchi, T Kawagoe, E Shibuya, T Yamane, ... Rheumatology 56 (11), 1918-1927, 2017 | 79 | 2017 |
| Heme oxygenase 1 attenuates the development of atopic dermatitis–like lesions in mice: Implications for human disease M Kirino, Y Kirino, M Takeno, Y Nagashima, K Takahashi, M Kobayashi, ... Journal of Allergy and Clinical Immunology 122 (2), 290-297. e8, 2008 | 73 | 2008 |
| A single endoplasmic reticulum aminopeptidase-1 protein allotype is a strong risk factor for Behçet's disease in HLA-B* 51 carriers M Takeuchi, MJ Ombrello, Y Kirino, B Erer, I Tugal-Tutkun, E Seyahi, ... Annals of the rheumatic diseases 75 (12), 2208-2211, 2016 | 72 | 2016 |
| Risk prediction modeling based on a combination of initial serum biomarker levels in polymyositis/dermatomyositis–associated interstitial lung disease T Gono, K Masui, N Nishina, Y Kawaguchi, A Kawakami, K Ikeda, Y Kirino, ... Arthritis & Rheumatology 73 (4), 677-686, 2021 | 69 | 2021 |
| The predictive prognostic factors for polymyositis/dermatomyositis-associated interstitial lung disease Y Sugiyama, R Yoshimi, M Tamura, M Takeno, Y Kunishita, D Kishimoto, ... Arthritis research & therapy 20, 1-10, 2018 | 69 | 2018 |
| Continuous evolution of clinical phenotype in 578 Japanese patients with Behçet’s disease: a retrospective observational study Y Kirino, H Ideguchi, M Takeno, A Suda, K Higashitani, Y Kunishita, ... Arthritis research & therapy 18, 1-8, 2016 | 65 | 2016 |
Michael J. OmbrelloPrincipal Investigator, Translational Genetics and Genomics Section, NIAMS, NIHVerified email at mail.nih.gov
