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| C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking MA Farg, V Sundaramoorthy, JM Sultana, S Yang, RAK Atkinson, ... Human molecular genetics 23 (13), 3579-3595, 2014 | 600 | 2014 |
| RETRACTED: Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis JD Atkin, MA Farg, AK Walker, C McLean, D Tomas, MK Horne Neurobiology of disease 30 (3), 400-407, 2008 | 455 | 2008 |
| Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1 JD Atkin, MA Farg, BJ Turner, D Tomas, JA Lysaght, J Nunan, A Rembach, ... Journal of Biological Chemistry 281 (40), 30152-30165, 2006 | 353 | 2006 |
| Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis BJ Turner, JD Atkin, MA Farg, A Rembach, EC Lopes, JD Patch, AF Hill, ... Journal of Neuroscience 25 (1), 108-117, 2005 | 228 | 2005 |
| CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia KL Williams, S Topp, S Yang, B Smith, JA Fifita, ST Warraich, KY Zhang, ... Nature communications 7 (1), 11253, 2016 | 221 | 2016 |
| ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formation AK Walker, KY Soo, V Sundaramoorthy, S Parakh, Y Ma, MA Farg, ... PloS one 8 (11), e81170, 2013 | 189 | 2013 |
| Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis AK Walker, MA Farg, CR Bye, CA McLean, MK Horne, JD Atkin Brain 133 (1), 105-116, 2010 | 181 | 2010 |
| The unfolded protein response and the role of protein disulfide isomerase in neurodegeneration ER Perri, CJ Thomas, S Parakh, DM Spencer, JD Atkin Frontiers in cell and developmental biology 3, 80, 2016 | 180 | 2016 |
| The complement factor C5a contributes to pathology in a rat model of amyotrophic lateral sclerosis TM Woodruff, KJ Costantini, JW Crane, JD Atkin, PN Monk, SM Taylor, ... The Journal of Immunology 181 (12), 8727-8734, 2008 | 169 | 2008 |
| Motor neuron susceptibility in ALS/FTD AMG Ragagnin, S Shadfar, M Vidal, MS Jamali, JD Atkin Frontiers in neuroscience 13, 532, 2019 | 168 | 2019 |
| The DNA damage response (DDR) is induced by the C9orf72 repeat expansion in amyotrophic lateral sclerosis MA Farg, A Konopka, KY Soo, D Ito, JD Atkin Human molecular genetics 26 (15), 2882-2896, 2017 | 158 | 2017 |
| The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins V Deora, JD Lee, EA Albornoz, L McAlary, CJ Jagaraj, AAB Robertson, ... Glia 68 (2), 407-421, 2020 | 155 | 2020 |
| Novel roles for protein disulphide isomerase in disease states: a double edged sword? S Parakh, JD Atkin Frontiers in cell and developmental biology 3, 30, 2015 | 146 | 2015 |
| Rab1-dependent ER–Golgi transport dysfunction is a common pathogenic mechanism in SOD1, TDP-43 and FUS-associated ALS KY Soo, M Halloran, V Sundaramoorthy, S Parakh, RP Toth, KA Southam, ... Acta neuropathologica 130, 679-697, 2015 | 132 | 2015 |
| Multifaceted deaths orchestrated by mitochondria in neurones P Nagley, GC Higgins, JD Atkin, PM Beart Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1802 (1), 167-185, 2010 | 129 | 2010 |
| Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis MA Farg, KY Soo, ST Warraich, V Sundaramoorthy, IP Blair, JD Atkin Human molecular genetics 22 (4), 717-728, 2013 | 127 | 2013 |
| Stress signaling from the endoplasmic reticulum: A central player in the pathogenesis of amyotrophic lateral sclerosis AK Walker, JD Atkin IUBMB life 63 (9), 754-763, 2011 | 121 | 2011 |
| Mutant FUS induces endoplasmic reticulum stress in amyotrophic lateral sclerosis and interacts with protein disulfide-isomerase MA Farg, KY Soo, AK Walker, H Pham, J Orian, MK Horne, ST Warraich, ... Neurobiology of aging 33 (12), 2855-2868, 2012 | 120 | 2012 |
| Protein folding alterations in amyotrophic lateral sclerosis S Parakh, JD Atkin Brain research 1648, 633-649, 2016 | 119 | 2016 |
