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Caleb Lareau
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Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
HK Finucane, YA Reshef, V Anttila, K Slowikowski, A Gusev, A Byrnes, ...
Nature genetics 50 (4), 621-629, 2018
8532018
Single-cell chromatin state analysis with Signac
T Stuart, A Srivastava, S Madad, CA Lareau, R Satija
Nature methods 18 (11), 1333-1341, 2021
743*2021
Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations
CP Fulco, J Nasser, TR Jones, G Munson, DT Bergman, V Subramanian, ...
Nature genetics 51 (12), 1664-1669, 2019
6552019
Chromatin potential identified by shared single-cell profiling of RNA and chromatin
S Ma, B Zhang, LM LaFave, AS Earl, Z Chiang, Y Hu, J Ding, A Brack, ...
Cell 183 (4), 1103-1116. e20, 2020
6342020
Integrated single-cell analysis maps the continuous regulatory landscape of human hematopoietic differentiation
JD Buenrostro, MR Corces, CA Lareau, B Wu, AN Schep, MJ Aryee, ...
Cell 173 (6), 1535-1548. e16, 2018
6212018
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors
J Grünewald, R Zhou, SP Garcia, S Iyer, CA Lareau, MJ Aryee, JK Joung
Nature 569 (7756), 433-437, 2019
5272019
The polygenic and monogenic basis of blood traits and diseases
D Vuckovic, EL Bao, P Akbari, CA Lareau, A Mousas, T Jiang, MH Chen, ...
Cell 182 (5), 1214-1231.e14, 2020
4212020
Lineage tracing in humans enabled by mitochondrial mutations and single-cell genomics
LS Ludwig, CA Lareau, JC Ulirsch, E Christian, C Muus, LH Li, K Pelka, ...
Cell 176 (6), 1325-1339. e22, 2019
3992019
Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations
MH Chen, LM Raffield, A Mousas, S Sakaue, JE Huffman, A Moscati, ...
Cell 182 (5), 1198-1213. e14, 2020
3942020
Droplet-based combinatorial indexing for massive-scale single-cell chromatin accessibility
CA Lareau, FM Duarte, JG Chew, VK Kartha, ZD Burkett, AS Kohlway, ...
Nature Biotechnology 37 (8), 916-924, 2019
3702019
The cis-regulatory atlas of the mouse immune system
H Yoshida, CA Lareau, RN Ramirez, SA Rose, B Maier, A Wroblewska, ...
Cell 176 (4), 897-912. e20, 2019
3162019
A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation
BC Michel, AR D’Avino, SH Cassel, N Mashtalir, ZM McKenzie, ...
Nature cell biology 20 (12), 1410-1420, 2018
3102018
The SARS-CoV-2 RNA–protein interactome in infected human cells
N Schmidt, CA Lareau, H Keshishian, S Ganskih, C Schneider, T Hennig, ...
Nature microbiology 6 (3), 339-353, 2021
2852021
CRISPR DNA base editors with reduced RNA off-target and self-editing activities
J Grünewald, R Zhou, S Iyer, CA Lareau, SP Garcia, MJ Aryee, JK Joung
Nature biotechnology 37 (9), 1041-1048, 2019
2792019
Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells
EP Mimitou, CA Lareau, KY Chen, AL Zorzetto-Fernandes, Y Hao, ...
Nature biotechnology 39 (10), 1246-1258, 2021
2772021
Assessment of computational methods for the analysis of single-cell ATAC-seq data
H Chen, C Lareau, T Andreani, ME Vinyard, SP Garcia, K Clement, ...
Genome biology 20, 1-25, 2019
2522019
Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM
H Chen, L Albergante, JY Hsu, CA Lareau, G Lo Bosco, J Guan, S Zhou, ...
Nature communications 10 (1), 1-14, 2019
2312019
A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing
J Grünewald, R Zhou, CA Lareau, SP Garcia, S Iyer, BR Miller, ...
Nature Biotechnology 38 (7), 861-864, 2020
2162020
Interrogation of human hematopoiesis at single-cell and single-variant resolution
JC Ulirsch, CA Lareau, EL Bao, LS Ludwig, MH Guo, C Benner, ...
Nature genetics 51 (4), 683-693, 2019
1752019
Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling
CA Lareau, LS Ludwig, C Muus, SH Gohil, T Zhao, Z Chiang, K Pelka, ...
Nature biotechnology 39 (4), 451-461, 2021
1702021
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Articles 1–20