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Diether Lambrechts
Diether Lambrechts
Laboratory for Translational Genetics, Department of Oncology, VIB and KULeuven, Leuven, Belgium
Verified email at vib-kuleuven.be
Title
Cited by
Cited by
Year
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective …
W De Roock, B Claes, D Bernasconi, J De Schutter, B Biesmans, ...
The lancet oncology 11 (8), 753-762, 2010
25612010
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
BF Voight, GM Peloso, M Orho-Melander, R Frikke-Schmidt, M Barbalic, ...
The Lancet 380 (9841), 572-580, 2012
25112012
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
H Schunkert, IR König, S Kathiresan, MP Reilly, TL Assimes, H Holm, ...
Nature genetics 43 (4), 333-338, 2011
21792011
Association analysis identifies 65 new breast cancer risk loci
K Michailidou, S Lindström, J Dennis, J Beesley, S Hui, S Kar, A Lemaçon, ...
Nature 551 (7678), 92-94, 2017
12902017
Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial
TS Maughan, RA Adams, CG Smith, AM Meade, MT Seymour, RH Wilson, ...
The Lancet 377 (9783), 2103-2114, 2011
12652011
Large-scale genotyping identifies 41 new loci associated with breast cancer risk
K Michailidou, P Hall, A Gonzalez-Neira, M Ghoussaini, J Dennis, ...
Nature genetics 45 (4), 353-361, 2013
12562013
Phenotype molding of stromal cells in the lung tumor microenvironment
D Lambrechts, E Wauters, B Boeckx, S Aibar, D Nittner, O Burton, ...
Nature medicine 24 (8), 1277-1289, 2018
12162018
VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death
D Lambrechts, E Storkebaum, M Morimoto, J Del-Favero, F Desmet, ...
Nature genetics 34 (4), 383-394, 2003
11142003
Gene prioritization through genomic data fusion
S Aerts, D Lambrechts, S Maity, P Van Loo, B Coessens, F De Smet, ...
Nature biotechnology 24 (5), 537-544, 2006
11082006
Role of PlGF in the intra-and intermolecular cross talk between the VEGF receptors Flt1 and Flk1
M Autiero, J Waltenberger, D Communi, A Kranz, L Moons, D Lambrechts, ...
Nature medicine 9 (7), 936-943, 2003
10152003
Polygenic risk scores for prediction of breast cancer and breast cancer subtypes
N Mavaddat, K Michailidou, J Dennis, M Lush, L Fachal, A Lee, JP Tyrer, ...
The American Journal of Human Genetics 104 (1), 21-34, 2019
8862019
Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies
XR Yang, J Chang-Claude, EL Goode, FJ Couch, H Nevanlinna, RL Milne, ...
Journal of the National Cancer Institute 103 (3), 250-263, 2011
8362011
Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer
KL Bolton, G Chenevix-Trench, C Goh, S Sadetzki, SJ Ramus, BY Karlan, ...
Jama 307 (4), 382-389, 2012
7252012
VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection
E Storkebaum, D Lambrechts, P Carmeliet
Bioessays 26 (9), 943-954, 2004
6982004
Prediction of breast cancer risk based on profiling with common genetic variants
N Mavaddat, PDP Pharoah, K Michailidou, J Tyrer, MN Brook, MK Bolla, ...
Journal of the National Cancer Institute 107 (5), djv036, 2015
6652015
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
K Michailidou, J Beesley, S Lindstrom, S Canisius, J Dennis, MJ Lush, ...
Nature genetics 47 (4), 373-380, 2015
6472015
Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations
YC Lin, M Boone, L Meuris, I Lemmens, N Van Roy, A Soete, J Reumers, ...
Nature communications 5 (1), 4767, 2014
6442014
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
SE Bojesen, KA Pooley, SE Johnatty, J Beesley, K Michailidou, JP Tyrer, ...
Nature genetics 45 (4), 371-384, 2013
6422013
Thrombomodulin mutations in atypical hemolytic–uremic syndrome
M Delvaeye, M Noris, A De Vriese, CT Esmon, NL Esmon, G Ferrell, ...
New England Journal of Medicine 361 (4), 345-357, 2009
6392009
Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS
E Storkebaum, D Lambrechts, M Dewerchin, MP Moreno-Murciano, ...
Nature neuroscience 8 (1), 85-92, 2005
6192005
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