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| Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape C Lu, SU Jain, D Hoelper, D Bechet, RC Molden, L Ran, D Murphy, ... Science 352 (6287), 844-849, 2016 | 373 | 2016 |
| H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis AS Harutyunyan, B Krug, H Chen, S Papillon-Cavanagh, M Zeinieh, ... Nature communications 10 (1), 1262, 2019 | 260 | 2019 |
| mRMRe: an R package for parallelized mRMR ensemble feature selection N De Jay, S Papillon-Cavanagh, C Olsen, N El-Hachem, G Bontempi, ... Bioinformatics 29 (18), 2365-2368, 2013 | 253 | 2013 |
| H3. 3K27M cooperates with Trp53 loss and PDGFRA gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas M Pathania, N De Jay, N Maestro, AS Harutyunyan, J Nitarska, ... Cancer cell 32 (5), 684-700. e9, 2017 | 229 | 2017 |
| Stalled developmental programs at the root of pediatric brain tumors S Jessa, A Blanchet-Cohen, B Krug, M Vladoiu, M Coutelier, D Faury, ... Nature genetics 51 (12), 1702-1713, 2019 | 184 | 2019 |
| Pervasive H3K27 acetylation leads to ERV expression and a therapeutic vulnerability in H3K27M gliomas B Krug, N De Jay, AS Harutyunyan, S Deshmukh, DM Marchione, ... Cancer cell 35 (5), 782-797. e8, 2019 | 175 | 2019 |
| Histone H3. 3G34-mutant interneuron progenitors co-opt PDGFRA for gliomagenesis CCL Chen, S Deshmukh, S Jessa, D Hadjadj, V Lisi, AF Andrade, D Faury, ... Cell 183 (6), 1617-1633. e22, 2020 | 112 | 2020 |
| Comparison and validation of genomic predictors for anticancer drug sensitivity S Papillon-Cavanagh, N De Jay, N Hachem, C Olsen, G Bontempi, ... Journal of the American Medical Informatics Association 20 (4), 597-602, 2013 | 82 | 2013 |
| TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw CC Gomes, T Gayden, A Bajic, OF Harraz, J Pratt, H Nikbakht, E Bareke, ... Nature communications 9 (1), 4572, 2018 | 72 | 2018 |
| Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas R Salloum, MK McConechy, LG Mikael, C Fuller, R Drissi, M DeWire, ... Acta neuropathologica communications 5, 1-12, 2017 | 59 | 2017 |
| The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression R Ahn, V Sabourin, AM Bolt, S Hébert, S Totten, N De Jay, MC Festa, ... Nature communications 8 (1), 14638, 2017 | 59 | 2017 |
| Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles N Tawil, R Bassawon, B Meehan, A Nehme, L Montermini, T Gayden, ... Blood advances 5 (6), 1682-1694, 2021 | 54 | 2021 |
| H3. 3 G34W promotes growth and impedes differentiation of osteoblast-like mesenchymal progenitors in giant cell tumor of bone S Khazaei, N De Jay, S Deshmukh, LD Hendrikse, W Jawhar, CCL Chen, ... Cancer discovery 10 (12), 1968-1987, 2020 | 53 | 2020 |
| Mutant H3 histones drive human pre-leukemic hematopoietic stem cell expansion and promote leukemic aggressiveness M Boileau, M Shirinian, T Gayden, AS Harutyunyan, CCL Chen, ... Nature communications 10 (1), 2891, 2019 | 51 | 2019 |
| HIV-1 infection causes a down-regulation of genes involved in ribosome biogenesis CL Kleinman, M Doria, E Orecchini, E Giuliani, S Galardi, N De Jay, ... PloS one 9 (12), e113908, 2014 | 28 | 2014 |
| Non-random aneuploidy specifies subgroups of pilocytic astrocytoma and correlates with older age AM Fontebasso, M Shirinian, DA Khuong-Quang, D Bechet, T Gayden, ... Oncotarget 6 (31), 31844, 2015 | 16 | 2015 |
| Tungsten blocks murine b lymphocyte differentiation and proliferation through downregulation of il-7 receptor/pax5 signaling TH Wu, AM Bolt, H Chou, D Plourde, N De Jay, C Guilbert, YK Young, ... Toxicological sciences 170 (1), 45-56, 2019 | 13 | 2019 |
| Identification of genes functionally involved in the detrimental effects of mutant histone H3.3-K27M in Drosophila melanogaster J Berlandi, A Chaouch, N De Jay, I Tegeder, K Thiel, M Shirinian, ... Neuro-oncology 21 (5), 628-639, 2019 | 8 | 2019 |
| Murine diet/tissue and human brain tumorigenesis alter Mthfr/MTHFR 5′-end methylation N Lévesque, D Leclerc, T Gayden, A Lazaris, N De Jay, S Petrillo, ... Mammalian Genome 27, 122-134, 2016 | 5 | 2016 |
