|Mechanisms of stem cell self-renewal|
HE Shenghui, D Nakada, SJ Morrison
Annual Review of Cell and Developmental 25, 377-406, 2009
|Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells|
D Nakada, TL Saunders, SJ Morrison
Nature 468 (7324), 653-658, 2010
|ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanism|
D Nakada, K Matsumoto, K Sugimoto
Genes & development 17 (16), 1957-1962, 2003
|Oestrogen increases haematopoietic stem-cell self-renewal in females and during pregnancy|
D Nakada, H Oguro, BP Levi, N Ryan, A Kitano, Y Saitoh, M Takeichi, ...
Nature 505 (7484), 555-558, 2014
|mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion|
JY Lee, D Nakada, OH Yilmaz, Z Tothova, NM Joseph, MS Lim, ...
Cell stem cell 7 (5), 593-605, 2010
|Inhibition of AMPK catabolic action by GSK3|
T Suzuki, D Bridges, D Nakada, G Skiniotis, SJ Morrison, JD Lin, ...
Molecular cell 50 (3), 407-419, 2013
|Highly efficient genome editing of murine and human hematopoietic progenitor cells by CRISPR/Cas9|
MC Gundry, L Brunetti, A Lin, AE Mayle, A Kitano, D Wagner, JI Hsu, ...
Cell reports 17 (5), 1453-1461, 2016
|Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression|
JA Magee, T Ikenoue, D Nakada, JY Lee, KL Guan, SJ Morrison
Cell stem cell 11 (3), 415-428, 2012
|AMPK protects leukemia-initiating cells in myeloid leukemias from metabolic stress in the bone marrow|
Y Saito, RH Chapple, A Lin, A Kitano, D Nakada
Cell stem cell 17 (5), 585-596, 2015
|Requirement of the Mre11 complex and exonuclease 1 for activation of the Mec1 signaling pathway|
D Nakada, Y Hirano, K Sugimoto
Molecular and cellular biology 24 (22), 10016-10025, 2004
|Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain|
JK Mich, RAJ Signer, D Nakada, A Pineda, RJ Burgess, TY Vue, ...
Elife 3, e02669, 2014
|Clamp and clamp loader structures of the human checkpoint protein complexes, Rad9‐1‐1 and Rad17‐RFC|
Y Shiomi, A Shinozaki, D Nakada, K Sugimoto, J Usukura, C Obuse, ...
Genes to Cells 7 (8), 861-868, 2002
|Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway|
T Naiki, T Kondo, D Nakada, K Matsumoto, K Sugimoto
Molecular and cellular biology 21 (17), 5838-5845, 2001
|Energy-stress-mediated AMPK activation inhibits ferroptosis|
H Lee, F Zandkarimi, Y Zhang, JK Meena, J Kim, L Zhuang, S Tyagi, L Ma, ...
Nature cell biology 22 (2), 225-234, 2020
|Integrating physiological regulation with stem cell and tissue homeostasis|
D Nakada, BP Levi, SJ Morrison
Neuron 70 (4), 703-718, 2011
|Association of Rad9 with double-strand breaks through a Mec1-dependent mechanism|
T Naiki, T Wakayama, D Nakada, K Matsumoto, K Sugimoto
Molecular and cellular biology 24 (8), 3277-3285, 2004
|The ATM‐related Tel1 protein of Saccharomyces cerevisiae controls a checkpoint response following phleomycin treatment|
D Nakada, T Shimomura, K Matsumoto, K Sugimoto
Nucleic acids research 31 (6), 1715-1724, 2003
|Role of the C terminus of Mec1 checkpoint kinase in its localization to sites of DNA damage|
D Nakada, Y Hirano, Y Tanaka, K Sugimoto
Molecular biology of the cell 16 (11), 5227-5235, 2005
|Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics|
K Morita, F Wang, K Jahn, T Hu, T Tanaka, Y Sasaki, J Kuipers, S Loghavi, ...
Nature communications 11 (1), 1-17, 2020
|The cytosolic protein G0S2 maintains quiescence in hematopoietic stem cells|
T Yamada, CS Park, A Burns, D Nakada, HD Lacorazza
PloS one 7 (5), e38280, 2012