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Iris A. L. Silva
Iris A. L. Silva
Assistant researcher, S2AQUAcoLAB
Verified email at s2aquacolab.pt
Title
Cited by
Cited by
Year
Protocol for application, standardization and validation of the forskolin-induced swelling assay in cystic fibrosis human colon organoids
AM Vonk, P van Mourik, AS Ramalho, IAL Silva, M Statia, E Kruisselbrink, ...
STAR protocols 1 (1), 100019, 2020
872020
MiR-29a is an enhancer of mineral deposition in bone-derived systems
VP Roberto, DM Tiago, IAL Silva, ML Cancela
Archives of biochemistry and biophysics 564, 173-183, 2014
412014
Mutant CFTR Drives TWIST1 mediated epithelial–mesenchymal transition
MC Quaresma, I Pankonien, LA Clarke, LS Sousa, IAL Silva, V Railean, ...
Cell Death & Disease 11 (10), 920, 2020
392020
Pharmacological modulation of ion channels for the treatment of cystic fibrosis
MC Pinto, IAL Silva, MF Figueira, MD Amaral, M Lopes-Pacheco
Journal of Experimental Pharmacology, 693-723, 2021
382021
TMEM16A chloride channel does not drive mucus production
FB Simões, MC Quaresma, LA Clarke, IAL Silva, I Pankonien, V Railean, ...
Life science alliance 2 (6), 2019
342019
R560S: A class II CFTR mutation that is not rescued by current modulators
NT Awatade, S Ramalho, IAL Silva, V Felício, HM Botelho, E de Poel, ...
Journal of Cystic Fibrosis 18 (2), 182-189, 2019
342019
A novel microscopy-based assay identifies extended synaptotagmin-1 (ESYT1) as a positive regulator of anoctamin 1 traffic
JR Lérias, MC Pinto, HM Botelho, NT Awatade, MC Quaresma, IAL Silva, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1865 (2), 421-431, 2018
302018
The effect of premature termination codon mutations on CFTR mRNA abundance in human nasal epithelium and intestinal organoids: a basis for read‐through …
LA Clarke, NT Awatade, VM Felício, IA Silva, M Calucho, L Pereira, ...
Human mutation 40 (3), 326-334, 2019
292019
Effect of genetic variants of OPTN in the pathophysiology of Paget's disease of bone
IAL Silva, N Conceição, É Gagnon, H Caiado, JP Brown, F Gianfrancesco, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (1), 143-151, 2018
242018
Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia
GD Amatngalim, LW Rodenburg, BL Aalbers, HHM Raeven, EM Aarts, ...
Life Science Alliance 5 (12), 2022
232022
Personalized medicine based on nasal epithelial cells: comparative studies with rectal biopsies and intestinal organoids
IAL Silva, V Railean, A Duarte, MD Amaral
Journal of Personalized Medicine 11 (5), 421, 2021
212021
Synergy in cystic fibrosis therapies: targeting SLC26A9
MC Pinto, MC Quaresma, IAL Silva, V Railean, SS Ramalho, MD Amaral
International journal of molecular sciences 22 (23), 13064, 2021
192021
Advances in preclinical in vitro models for the translation of precision medicine for cystic fibrosis
IAL Silva, O Laselva, M Lopes-Pacheco
Journal of Personalized Medicine 12 (8), 1321, 2022
172022
Molecular characterization of two paralog genes encoding Gla‐rich protein (Grp) in zebrafish
C Fazenda, IAL Silva, ML Cancela, N Conceição
Journal of Applied Ichthyology 28 (3), 377-381, 2012
172012
Characterization of the mechanism of action of RDR01752, a novel corrector of F508del-CFTR
M Lopes-Pacheco, IAL Silva, MJ Turner, GW Carlile, E Sondo, ...
Biochemical Pharmacology 180, 114133, 2020
162020
Rare trafficking CFTR mutations involve distinct cellular retention machineries and require different rescuing strategies
SS Ramalho, IAL Silva, MD Amaral, CM Farinha
International Journal of Molecular Sciences 23 (1), 24, 2021
142021
KLF4 Acts as a wt-CFTR Suppressor through an AKT-Mediated Pathway
L Sousa, I Pankonien, LA Clarke, I Silva, K Kunzelmann, MD Amaral
Cells 9 (7), 1607, 2020
142020
Organoids as a personalized medicine tool for ultra-rare mutations in cystic fibrosis: The case of S955P and 1717-2A> G
IAL Silva, T Doušová, S Ramalho, R Centeio, LA Clarke, V Railean, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (11), 165905, 2020
122020
Molecular effect of an OPTN common variant associated to Paget's disease of bone
IAL Silva, N Conceição, E Gagnon, JP Brown, ML Cancela, L Michou
Plos one 13 (5), e0197543, 2018
122018
Rescue of mutant CFTR trafficking defect by the investigational compound MCG1516A
M Lopes-Pacheco, M Bacalhau, SS Ramalho, IAL Silva, FC Ferreira, ...
Cells 11 (1), 136, 2022
112022
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Articles 1–20