| Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG MKB Jonsson, MA Vos, GR Mirams, G Duker, P Sartipy, TP de Boer, ... Journal of molecular and cellular cardiology 52 (5), 998-1008, 2012 | 162 | 2012 |
| Lessons from the heart: Mirroring electrophysiological characteristics during cardiac development to in vitro differentiation of stem cell derived cardiomyocytes NHL van den Heuvel, TAB van Veen, B Lim, MKB Jonsson Journal of Molecular and Cellular Cardiology 67, 12-25, 2014 | 109 | 2014 |
| Impedance-based detection of beating rhythm and proarrhythmic effects of compounds on stem cell-derived cardiomyocytes MKB Jonsson, QD Wang, B Becker Assay and Drug Development Technologies 9 (6), 589-599, 2011 | 104 | 2011 |
| Gender disparity in cardiac electrophysiology: implications for cardiac safety pharmacology MKB Jonsson, MA Vos, G Duker, S Demolombe, TAB Van Veen Pharmacology & therapeutics 127 (1), 9-18, 2010 | 99 | 2010 |
| Quantified proarrhythmic potential of selected human embryonic stem cell-derived cardiomyocytes MKB Jonsson, G Duker, C Tropp, B Andersson, P Sartipy, MA Vos, ... Stem Cell Research 4 (3), 189-200, 2010 | 89 | 2010 |
| Epigenetics: DNA demethylation promotes skeletal myotube maturation M Hupkes, MKB Jonsson, WJ Scheenen, W van Rotterdam, AM Sotoca, ... The FASEB Journal 25 (11), 3861-3872, 2011 | 76 | 2011 |
| Comparison of IKr blocking drugs Moxifloxacin and Dofetilide/E‐4031 in 5 screening models of pro‐arrhythmia reveals insufficient specificity of isolated cardiomyocytes L Nalos, R Varkevisser, MKB Jonsson, MJC Houtman, JD Beekman, ... British Journal of Pharmacology, 2011 | 76* | 2011 |
| Transient compartment-like syndrome and normokalaemic periodic paralysis due to a Cav1. 1 mutation C Fan, F Lehmann-Horn, MA Weber, M Bednarz, JR Groome, ... Brain 136 (12), 3775-3786, 2013 | 49 | 2013 |
| Human cardiomyocyte progenitor cell-derived cardiomyocytes display a maturated electrical phenotype TP de Boer, TAB van Veen, MKB Jonsson, BGJM Kok, CHG Metz, ... Journal of molecular and cellular cardiology 48 (1), 254-260, 2010 | 44 | 2010 |
| A transcriptomic and epigenomic comparison of fetal and adult human cardiac fibroblasts reveals novel key transcription factors in adult cardiac fibroblasts MKB Jonsson, RJG Hartman, M Ackers-Johnson, WLW Tan, B Lim, ... JACC: Basic to Translational Science 1 (7), 590-602, 2016 | 40 | 2016 |
| Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa, are IKr blockers with proarrhythmic effects in vitro and in vivo I Baburin, R Varkevisser, A Schramm, P Saxena, S Beyl, P Szkokan, ... Pharmacological research 131, 150-163, 2018 | 38 | 2018 |
| Inhibiting cardiac myeloperoxidase alleviates the relaxation defect in hypertrophic cardiomyocytes CJA Ramachandra, MMJ Kp, J Chua, S Hernandez-Resendiz, EA Liehn, ... Cardiovascular Research 118 (2), 517-530, 2022 | 33 | 2022 |
| Improvement of cardiac efficacy and safety models in drug discovery by the use of stem cell-derived cardiomyocytes MKB Jonsson, TAB van Veen, MJ Goumans, MA Vos, G Duker, P Sartipy Expert opinion on drug discovery 4 (4), 357-372, 2009 | 28 | 2009 |
| Deciphering hERG channels: Molecular basis of the rapid component of the delayed rectifier potassium current MKB Jonsson, MAG van der Heyden, TAB van Veen Journal of Molecular and Cellular Cardiology 53 (3), 369-374, 2012 | 24 | 2012 |
| Rewiring the heart: stem cell therapy to restore normal cardiac excitability and conduction AC Blank, TAB van Veen, MKB Jonsson, JSJ Zelen, JL Strengers, ... Current Stem Cell Research & Therapy 4 (1), 23-33, 2009 | 17 | 2009 |
| Towards Creating the Perfect In Vitro Cell Model MKB Jonsson, TAB van Veen, J Synnergren, B Becker Stem cells international 2016, 2016 | 11 | 2016 |
| The influence of hERG1a and hERG1b isoforms on drug safety screening in iPSC-CMs B Goversen, MKB Jonsson, NHL van den Heuvel, R Rijken, MA Vos, ... Progress in biophysics and molecular biology 149, 86-98, 2019 | 9 | 2019 |
| Personalized medicine and the role of induced pluripotent stem cells MAG van der Heyden, MKB Jonsson Cardiovascular Research 95 (4), 395-396, 2012 | 7 | 2012 |
| Evaluation of therapeutic strategies targeting BCAA catabolism using a systems pharmacology model SM Voronova V, Sokolov V, Morias Y, Jonsson Boezelman MKB, Wågberg M ... Front Pharmacol. 13 (993422), doi: 10.3389/fphar.2022.993422. eCollect, 2022 | 6* | 2022 |
| Metabolic perturbations in hypertrophic cardiomyopathy–Insights from human induced pluripotent stem cell-derived cardiomyocytes C Ramachandra, S Cong, EP Yap, MMJ Kp, A Foinquinos, M Jonsson, ... Journal of Molecular and Cellular Cardiology 173, 120-121, 2022 | | 2022 |
Teun P. de BoerAssociate Professor, Department of Medical Physiology, University Medical Center UtrechtGeverifieerd e-mailadres voor umcutrecht.nl
