| PBPK models for the prediction of in vivo performance of oral dosage forms ES Kostewicz, L Aarons, M Bergstrand, MB Bolger, A Galetin, O Hatley, ... European Journal of Pharmaceutical Sciences 57, 300-321, 2014 | 330 | 2014 |
| Application of physiologically based pharmacokinetic (PBPK) modeling to support dose selection: report of an FDA public workshop on PBPK C Wagner, P Zhao, Y Pan, V Hsu, J Grillo, SM Huang, V Sinha CPT: pharmacometrics & systems pharmacology 4 (4), 226-230, 2015 | 282 | 2015 |
| Predicting the effect of cytochrome P450 inhibitors on substrate drugs: analysis of physiologically based pharmacokinetic modeling submissions to the US Food and Drug … C Wagner, Y Pan, V Hsu, JA Grillo, L Zhang, KS Reynolds, V Sinha, ... Clinical pharmacokinetics 54, 117-127, 2015 | 134 | 2015 |
| Biorelevant in vitro dissolution testing of products containing micronized or nanosized fenofibrate with a view to predicting plasma profiles D Juenemann, E Jantratid, C Wagner, C Reppas, M Vertzoni, ... European journal of pharmaceutics and biopharmaceutics 77 (2), 257-264, 2011 | 125 | 2011 |
| Predicting the effect of CYP3A inducers on the pharmacokinetics of substrate drugs using physiologically based pharmacokinetic (PBPK) modeling: an analysis of PBPK submissions … C Wagner, Y Pan, V Hsu, V Sinha, P Zhao Clinical pharmacokinetics 55, 475-483, 2016 | 95 | 2016 |
| Predicting the oral absorption of a poorly soluble, poorly permeable weak base using biorelevant dissolution and transfer model tests coupled with a physiologically based … C Wagner, E Jantratid, F Kesisoglou, M Vertzoni, C Reppas, JB Dressman European journal of pharmaceutics and biopharmaceutics 82 (1), 127-138, 2012 | 93 | 2012 |
| Predictive performance of physiologically based pharmacokinetic models for the effect of food on oral drug absorption: current status M Li, P Zhao, Y Pan, C Wagner CPT: pharmacometrics & systems pharmacology 7 (2), 82-89, 2018 | 88 | 2018 |
| Use of physiologically based pharmacokinetic (PBPK) modeling for predicting drug-food interactions: an industry perspective AE Riedmaier, K DeMent, J Huckle, P Bransford, C Stillhart, R Lloyd, ... The AAPS journal 22, 1-15, 2020 | 70 | 2020 |
| Utilizing in vitro and PBPK tools to link ADME characteristics to plasma profiles: case example nifedipine immediate release formulation C Wagner, K Thelen, S Willmann, A Selen, JB Dressman Journal of Pharmaceutical Sciences 102 (9), 3205-3219, 2013 | 37 | 2013 |
| Prediction of in-vivo pharmacokinetic profile for immediate and modified release oral dosage forms of furosemide using an in-vitro–in-silico–in-vivo approach K Otsuka, C Wagner, A Selen, J Dressman Journal of Pharmacy and Pharmacology 67 (5), 651-665, 2015 | 30 | 2015 |
| Best practices in the development and validation of physiologically based biopharmaceutics modeling. A workshop summary report N Parrott, S Suarez-Sharp, F Kesisoglou, SM Pathak, D Good, C Wagner, ... Journal of Pharmaceutical Sciences 110 (2), 584-593, 2021 | 28 | 2021 |
| Use of physiologically based pharmacokinetic modeling for predicting drug–food interactions: Recommendations for improving predictive performance of low confidence food effect … C Wagner, F Kesisoglou, XJH Pepin, N Parrott, A Emami Riedmaier The AAPS Journal 23 (4), 85, 2021 | 26 | 2021 |
| Improved prediction of in vivo supersaturation and precipitation of poorly soluble weakly basic drugs using a biorelevant bicarbonate buffer in a gastrointestinal transfer model C Jede, C Wagner, H Kubas, M Weigandt, C Weber, M Lecomte, L Badolo, ... Molecular Pharmaceutics 16 (9), 3938-3947, 2019 | 24 | 2019 |
| PDA/FDA Glass Quality Conference: an alternative glass packing solution to reduce delamination risks C Wagner PowerPoint Presentation] PDA/FDA Glass Quality Conference, Washington, DC, 2012 | 22 | 2012 |
| The effect of buffer species on biorelevant dissolution and precipitation assays–Comparison of phosphate and bicarbonate buffer K Krollik, A Lehmann, C Wagner, J Kaidas, H Kubas, W Weitschies European Journal of Pharmaceutics and Biopharmaceutics 171, 90-101, 2022 | 19 | 2022 |
| Chapter 12: In Vitro - in Silico Tools to Predict Pharmacokinetics of Poorly Soluble Drug Compounds C Wagner, JB Dressman Predictive ADMET: Integrated Approaches in Drug Discovery and Development, 2014 | 19* | 2014 |
| In-line derivative spectroscopy as a promising application to a small-scale in vitro transfer model in biorelevant supersaturation and precipitation testing C Jede, C Wagner, H Kubas, C Weber, W Weitschies Journal of Pharmacy and Pharmacology 70 (10), 1315-1323, 2018 | 17 | 2018 |
| Physiologically based pharmacokinetic modeling for predicting the effect of intrinsic and extrinsic factors on darunavir or lopinavir exposure coadministered with ritonavir C Wagner, P Zhao, V Arya, C Mullick, K Struble, S Au The Journal of Clinical Pharmacology 57 (10), 1295-1304, 2017 | 16 | 2017 |
| Automated small-scale in vitro transfer model as screening tool for the prediction of in vivo-dissolution and precipitation of poorly solubles C Jede, C Wagner, H Kubas, C Weber, M Weigandt, M Koziolek, ... International journal of pharmaceutics 556, 150-158, 2019 | 11 | 2019 |
| Impact of amorphization and GI physiology on supersaturation and precipitation of poorly soluble weakly basic drugs using a small-scale in vitro transfer model C Auch, C Jede, M Harms, C Wagner, K Mäder International Journal of Pharmaceutics 574, 118917, 2020 | 9 | 2020 |
Jennifer DressmanGoethe UniversityGeverifieerd e-mailadres voor em.uni-frankfurt.de
