Eric Eldering
Eric Eldering
Academic Medical Center
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The clinically active BTK inhibitor PCI-32765 targets B-cell receptor–and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia
MFM de Rooij, A Kuil, CR Geest, E Eldering, BY Chang, JJ Buggy, ...
Blood, The Journal of the American Society of Hematology 119 (11), 2590-2594, 2012
CD20 deficiency in humans results in impaired T cell–independent antibody responses
TW Kuijpers, RJ Bende, PA Baars, A Grummels, IAM Derks, KM Dolman, ...
The Journal of clinical investigation 120 (1), 214-222, 2010
miR-34a as part of the resistance network in chronic lymphocytic leukemia
T Zenz, J Mohr, E Eldering, AP Kater, A Bühler, D Kienle, D Winkler, ...
Blood, The Journal of the American Society of Hematology 113 (16), 3801-3808, 2009
Expression profiling via novel multiplex assay allows rapid assessment of gene regulation in defined signalling pathways
E Eldering, CA Spek, HL Aberson, A Grummels, IA Derks, AF de Vos, ...
Nucleic acids research 31 (23), e153-e153, 2003
Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue
AM Grabiec, S Krausz, W De Jager, T Burakowski, D Groot, ME Sanders, ...
The journal of immunology 184 (5), 2718-2728, 2010
The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells
NL Alves, IAM Derks, E Berk, R Spijker, RAW van Lier, E Eldering
Immunity 24 (6), 703-716, 2006
APRIL promotes B-1 cell-associated neoplasm
L Planelles, CE Carvalho-Pinto, G Hardenberg, S Smaniotto, W Savino, ...
Cancer cell 6 (4), 399-408, 2004
Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity
LA Smit, DYH Hallaert, R Spijker, B de Goeij, A Jaspers, AP Kater, ...
Blood 109 (4), 1660-1668, 2007
CD27–CD70 interactions sensitise naive CD4+ T cells for IL-12-induced Th1 cell development
MF Van Oosterwijk, H Juwana, R Arens, K Tesselaar, MHJ Van Oers, ...
International immunology 19 (6), 713-718, 2007
Potentiation of C1 inhibitor by glycosaminoglycans: dextran sulfate species are effective inhibitors of in vitro complement activation in plasma.
WA Wuillemin, H Te Velthuis, YT Lubbers, CP De Ruig, E Eldering, ...
The journal of immunology 159 (4), 1953-1960, 1997
c-Abl kinase inhibitors overcome CD40-mediated drug resistance in CLL: implications for therapeutic targeting of chemoresistant niches
DYH Hallaert, A Jaspers, CJ van Noesel, MHJ van Oers, AP Kater, ...
Blood, The Journal of the American Society of Hematology 112 (13), 5141-5149, 2008
IL-21 and CD40L signals from autologous T cells can induce antigen-independent proliferation of CLL cells
MF Pascutti, M Jak, JM Tromp, IAM Derks, EBM Remmerswaal, ...
Blood, The Journal of the American Society of Hematology 122 (17), 3010-3019, 2013
The costimulatory molecule CD27 maintains clonally diverse CD8+ T cell responses of low antigen affinity to protect against viral variants
KPJM van Gisbergen, PL Klarenbeek, NAM Kragten, PPA Unger, ...
Immunity 35 (1), 97-108, 2011
Venetoclax plus rituximab in relapsed chronic lymphocytic leukemia: 4-year results and evaluation of impact of genomic complexity and gene mutations from the MURANO phase III study
AP Kater, JQ Wu, T Kipps, B Eichhorst, P Hillmen, J D’rozario, S Assouline, ...
Journal of Clinical Oncology 38 (34), 4042, 2020
A hinge region mutation in C1-inhibitor (Ala436–> Thr) results in nonsubstrate-like behavior and in polymerization of the molecule.
KS Aulak, E Eldering, CE Hack, YP Lubbers, RA Harrison, A Mast, ...
Journal of Biological Chemistry 268 (24), 18088-18094, 1993
Resistance to ABT-199 induced by microenvironmental signals in chronic lymphocytic leukemia can be counteracted by CD20 antibodies or kinase inhibitors
R Thijssen, E Slinger, K Weller, CR Geest, T Beaumont, MHJ Van Oers, ...
Haematologica 100 (8), e302, 2015
Enhanced formation and survival of CD4+ CD25hi Foxp3+ T-cells in chronic lymphocytic leukemia
M Jak, M Jak, R Mous, EBM Remmerswaal, R Spijker, A Jaspers, ...
Leukemia & lymphoma 50 (5), 788-801, 2009
Modulation of contact system proteases by glycosaminoglycans: selective enhancement of the inhibition of factor XIa
WA Wuillemin, E Eldering, F Citarella, CP de Ruig, H ten Cate, CE Hack
Journal of Biological Chemistry 271 (22), 12913-12918, 1996
CD20-induced B cell death can bypass mitochondria and caspase activation
LE Van der Kolk, LM Evers, C Omene, SMA Lens, S Lederman, ...
Leukemia 16 (9), 1735-1744, 2002
CD40 stimulation of B‐cell chronic lymphocytic leukaemia cells enhances the anti‐apoptotic profile, but also Bid expression and cells remain susceptible to autologous cytotoxic …
AP Kater, LM Evers, EBM Remmerswaal, A Jaspers, MF Oosterwijk, ...
British journal of haematology 127 (4), 404-415, 2004
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