| Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 436 | 2021 |
| X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19 T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ... Science immunology 6 (62), eabl4348, 2021 | 325 | 2021 |
| A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection JL Casanova, HC Su, L Abel, A Aiuti, S Almuhsen, AA Arias, P Bastard, ... Cell 181 (6), 1194-1199, 2020 | 252 | 2020 |
| Weathering the COVID-19 storm: lessons from hematologic cytokine syndromes JT England, A Abdulla, CM Biggs, AYY Lee, KA Hay, RL Hoiland, ... Blood Reviews 45, 100707, 2021 | 202 | 2021 |
| DOCK8 deficiency: insights into pathophysiology, clinical features and management CM Biggs, S Keles, TA Chatila Clinical Immunology 181, 75-82, 2017 | 160 | 2017 |
| Practical guidance for the evaluation and management of drug hypersensitivity: specific drugs AD Broyles, A Banerji, S Barmettler, CM Biggs, K Blumenthal, PJ Brennan, ... The Journal of Allergy and Clinical Immunology: In Practice 8 (9), S16-S116, 2020 | 146 | 2020 |
| Life-threatening COVID-19: defective interferons unleash excessive inflammation Q Zhang, P Bastard, A Bolze, E Jouanguy, SY Zhang, A Cobat, ... Med 1 (1), 14-20, 2020 | 140 | 2020 |
| SARS-CoV-2–related MIS-C: A key to the viral and genetic causes of Kawasaki disease? V Sancho-Shimizu, P Brodin, A Cobat, CM Biggs, J Toubiana, CL Lucas, ... Journal of Experimental Medicine 218 (6), e20210446, 2021 | 138 | 2021 |
| The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 128 | 2022 |
| Innate immune control of EBV-infected B cells by invariant natural killer T cells BK Chung, K Tsai, LL Allan, DJ Zheng, JC Nie, CM Biggs, MR Hasan, ... Blood, The Journal of the American Society of Hematology 122 (15), 2600-2608, 2013 | 106 | 2013 |
| Calm in the midst of cytokine storm: a collaborative approach to the diagnosis and treatment of hemophagocytic lymphohistiocytosis and macrophage activation syndrome O Halyabar, MH Chang, ML Schoettler, MA Schwartz, EH Baris, ... Pediatric Rheumatology 17, 1-12, 2019 | 103 | 2019 |
| Inactivation of mammalian target of rapamycin increases STAT1 nuclear content and transcriptional activity in α4-and protein phosphatase 2A-dependent fashion JA Fielhaber, YS Han, J Tan, S Xing, CM Biggs, KB Joung, AS Kristof Journal of biological chemistry 284 (36), 24341-24353, 2009 | 60 | 2009 |
| Heterozygous FOXN1 variants cause low TRECs and severe T cell lymphopenia, revealing a crucial role of FOXN1 in supporting early thymopoiesis M Bosticardo, Y Yamazaki, J Cowan, G Giardino, C Corsino, G Scalia, ... The American Journal of Human Genetics 105 (3), 549-561, 2019 | 56 | 2019 |
| Germline CBM-opathies: from immunodeficiency to atopy HY Lu, CM Biggs, G Blanchard-Rohner, SY Fung, M Sharma, SE Turvey Journal of Allergy and Clinical Immunology 143 (5), 1661-1673, 2019 | 56 | 2019 |
| Soluble interleukin-6 receptor in the COVID-19 cytokine storm syndrome LYC Chen, CM Biggs, S Jamal, S Stukas, CL Wellington, MS Sekhon Cell Reports Medicine 2 (5), 2021 | 53 | 2021 |
| Hematopoietic stem cell transplantation outcomes for 11 patients with dedicator of cytokinesis 8 deficiency W Al-Herz, JI Chu, J van der Spek, R Raghupathy, MJ Massaad, S Keles, ... Journal of Allergy and Clinical Immunology 138 (3), 852-859. e3, 2016 | 53 | 2016 |
| Human germline heterozygous gain-of-function STAT6 variants cause severe allergic disease M Sharma, D Leung, M Momenilandi, LCW Jones, L Pacillo, AE James, ... Journal of Experimental Medicine 220 (5), e20221755, 2023 | 45 | 2023 |
| Amelioration of COVID‐19‐related cytokine storm syndrome: parallels to chimeric antigen receptor‐T cell cytokine release syndrome RL Hoiland, S Stukas, J Cooper, S Thiara, LYC Chen, CM Biggs, K Hay, ... British Journal of Haematology 190 (3), e150, 2020 | 39 | 2020 |
| First case of X-linked moesin deficiency identified after newborn screening for SCID OM Delmonte, CM Biggs, A Hayward, AM Comeau, HS Kuehn, ... Journal of clinical immunology 37, 336-338, 2017 | 38 | 2017 |
| Ruxolitinib as adjunctive therapy for secondary hemophagocytic lymphohistiocytosis: a case series S Hansen, W Alduaij, CM Biggs, S Belga, K Luecke, H Merkeley, ... European journal of haematology 106 (5), 654-661, 2021 | 33 | 2021 |
