A TALE nuclease architecture for efficient genome editing JC Miller, S Tan, G Qiao, KA Barlow, J Wang, DF Xia, X Meng, ... Nature biotechnology 29 (2), 143-148, 2011 | 2942 | 2011 |
Genetic engineering of human pluripotent cells using TALE nucleases D Hockemeyer, H Wang, S Kiani, CS Lai, Q Gao, JP Cassady, GJ Cost, ... Nature biotechnology 29 (8), 731-734, 2011 | 1551 | 2011 |
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases D Hockemeyer, F Soldner, C Beard, Q Gao, M Mitalipova, RC DeKelver, ... Nature biotechnology 27 (9), 851-857, 2009 | 1293 | 2009 |
Knockout rats via embryo microinjection of zinc-finger nucleases AM Geurts, GJ Cost, Y Freyvert, B Zeitler, JC Miller, VM Choi, SS Jenkins, ... Science 325 (5939), 433-433, 2009 | 1203 | 2009 |
Knockout rats via embryo microinjection of zinc-finger nucleases AM Geurts, GJ Cost, Y Freyvert, B Zeitler, JC Miller, VM Choi, SS Jenkins, ... Science 325 (5939), 433-433, 2009 | 1203 | 2009 |
Precise genome modification in the crop species Zea mays using zinc-finger nucleases VK Shukla, Y Doyon, JC Miller, RC DeKelver, EA Moehle, SE Worden, ... Nature 459 (7245), 437-441, 2009 | 1178 | 2009 |
Targeted genome editing across species using ZFNs and TALENs AJ Wood, TW Lo, B Zeitler, CS Pickle, EJ Ralston, AH Lee, R Amora, ... Science 333 (6040), 307-307, 2011 | 952 | 2011 |
Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases X Meng, MB Noyes, LJ Zhu, ND Lawson, SA Wolfe Nature biotechnology 26 (6), 695-701, 2008 | 945 | 2008 |
Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations F Soldner, J Laganière, AW Cheng, D Hockemeyer, Q Gao, R Alagappan, ... Cell 146 (2), 318-331, 2011 | 926 | 2011 |
Knockout rats generated by embryo microinjection of TALENs L Tesson, C Usal, S Ménoret, E Leung, BJ Niles, S Remy, Y Santiago, ... Nature biotechnology 29 (8), 695-696, 2011 | 818 | 2011 |
Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases J Hauschild, B Petersen, Y Santiago, AL Queisser, JW Carnwath, ... Proceedings of the National Academy of Sciences 108 (29), 12013-12017, 2011 | 471 | 2011 |
Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases J Hauschild, B Petersen, Y Santiago, AL Queisser, JW Carnwath, ... Proceedings of the National Academy of Sciences 108 (29), 12013-12017, 2011 | 471 | 2011 |
Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs J Chen, AA Shishkin, X Zhu, S Kadri, I Maza, M Guttman, JH Hanna, ... Genome biology 17, 1-17, 2016 | 423* | 2016 |
Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome RC DeKelver, VM Choi, EA Moehle, DE Paschon, D Hockemeyer, ... Genome research 20 (8), 1133-1142, 2010 | 367 | 2010 |
A bacterial one-hybrid system for determining the DNA-binding specificity of transcription factors X Meng, MH Brodsky, SA Wolfe Nature biotechnology 23 (8), 988-994, 2005 | 258 | 2005 |
Downstream divergence of the ethylene signaling pathway for harpin-stimulated Arabidopsis growth and insect defense HP Dong, J Peng, Z Bao, X Meng, JM Bonasera, G Chen, SV Beer, ... Plant Physiology 136 (3), 3628-3638, 2004 | 207 | 2004 |
A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system MB Noyes, X Meng, A Wakabayashi, S Sinha, MH Brodsky, SA Wolfe Nucleic acids research 36 (8), 2547-2560, 2008 | 206 | 2008 |
Identification of chromosome sequence motifs that mediate meiotic pairing and synapsis in C. elegans CM Phillips, X Meng, L Zhang, JH Chretien, FD Urnov, AF Dernburg Nature cell biology 11 (8), 934-942, 2009 | 151 | 2009 |
Zinc finger protein-dependent and -independent contributions to the in vivo off-target activity of zinc finger nucleases A Gupta, X Meng, LJ Zhu, ND Lawson, SA Wolfe Nucleic acids research 39 (1), 381-392, 2011 | 143 | 2011 |
Methods and compositions for modulating PD1 PD Gregory, MC Holmes, MC Mendel, X Meng, D Paschon, A Reik, ... US Patent 8,563,314, 2013 | 117 | 2013 |